Kawasaki disease in a five-month-old infant

Detalhes bibliográficos
Autor(a) principal: Maciel, Juliana
Data de Publicação: 2021
Outros Autores: Meireles, Daniel, Magalhães, Mariana, Gonçalves, Sara, Ribeiro Fernandes, Sofia, Fernandes, Paula Cristina
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10400.16/2526
Resumo: Introduction: Kawasaki disease, an acute self-limited vasculitis of small and medium arteries of unknown etiology, is the leading cause of heart disease in children in most developed countries. If untreated, it can lead to coronary artery dilatation and aneurysm, placing patients at risk for coronary thrombosis, myocardial infarction, or sudden death. Case Report: A previously healthy five-month-old boy presented with a history of respiratory symptoms and fever, being admitted for respiratory syncytial virus bronchiolitis. He maintained fever for five days associated with progressive clinical worsening and sequential development of conjunctival injection, cracked lips, swelling of hands and feet, and polymorphous rash of the limbs. Diagnostic procedures showed increased levels of inflammatory markers, hyponatremia, hypoalbuminemia, sterile pyuria, and aseptic meningitis. Despite an initial normal echocardiogram, Kawasaki disease was suspected and the boy started intravenous immunoglobulin on the fifth day. On the seventh day, echocardiogram showed signs of pancarditis and mild coronary artery ectasia and acetylsalicylic acid was started. The boy was discharged, but eight days later echocardiogram revealed major and diffuse coronary artery ectasia in a follow-up consultation and he was readmitted to start corticosteroid therapy. After five months, the boy displayed normalization of cardiac changes, without further complications. Comments: Kawasaki disease below six months of age is rare and associated with a high risk of coronary artery aneurysm. It is important to recognize the clinical and laboratory criteria associated with this entity and start early treatment, avoiding cardiac complications.
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spelling Kawasaki disease in a five-month-old infantDoença de Kwasaki num lactente de cinco mesesCoronary artery ectasiasudden infant death syndromeKawasaki DiseaseInfantIntroduction: Kawasaki disease, an acute self-limited vasculitis of small and medium arteries of unknown etiology, is the leading cause of heart disease in children in most developed countries. If untreated, it can lead to coronary artery dilatation and aneurysm, placing patients at risk for coronary thrombosis, myocardial infarction, or sudden death. Case Report: A previously healthy five-month-old boy presented with a history of respiratory symptoms and fever, being admitted for respiratory syncytial virus bronchiolitis. He maintained fever for five days associated with progressive clinical worsening and sequential development of conjunctival injection, cracked lips, swelling of hands and feet, and polymorphous rash of the limbs. Diagnostic procedures showed increased levels of inflammatory markers, hyponatremia, hypoalbuminemia, sterile pyuria, and aseptic meningitis. Despite an initial normal echocardiogram, Kawasaki disease was suspected and the boy started intravenous immunoglobulin on the fifth day. On the seventh day, echocardiogram showed signs of pancarditis and mild coronary artery ectasia and acetylsalicylic acid was started. The boy was discharged, but eight days later echocardiogram revealed major and diffuse coronary artery ectasia in a follow-up consultation and he was readmitted to start corticosteroid therapy. After five months, the boy displayed normalization of cardiac changes, without further complications. Comments: Kawasaki disease below six months of age is rare and associated with a high risk of coronary artery aneurysm. It is important to recognize the clinical and laboratory criteria associated with this entity and start early treatment, avoiding cardiac complications.Centro Hospitalar Universitário do PortoRepositório Científico do Centro Hospitalar Universitário de Santo AntónioMaciel, JulianaMeireles, DanielMagalhães, MarianaGonçalves, SaraRibeiro Fernandes, SofiaFernandes, Paula Cristina2021-11-04T09:42:23Z2021-062021-06-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.16/2526engMaciel J, Meireles D, Magalhães M, Gonçalves S, Ribeiro-Fernandes S, Fernandes PC, Nascer e Crescer - Birth and Growth Medical Journal 2021;30(2): 109-113. doi:10.25753/BirthGrowthMJ.v30.i2.190772183-941710.25753/BirthGrowthMJ.v30.i2.19077info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-10-20T11:01:00Zoai:repositorio.chporto.pt:10400.16/2526Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T20:38:44.065901Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Kawasaki disease in a five-month-old infant
Doença de Kwasaki num lactente de cinco meses
title Kawasaki disease in a five-month-old infant
spellingShingle Kawasaki disease in a five-month-old infant
Maciel, Juliana
Coronary artery ectasia
sudden infant death syndrome
Kawasaki Disease
Infant
title_short Kawasaki disease in a five-month-old infant
title_full Kawasaki disease in a five-month-old infant
title_fullStr Kawasaki disease in a five-month-old infant
title_full_unstemmed Kawasaki disease in a five-month-old infant
title_sort Kawasaki disease in a five-month-old infant
author Maciel, Juliana
author_facet Maciel, Juliana
Meireles, Daniel
Magalhães, Mariana
Gonçalves, Sara
Ribeiro Fernandes, Sofia
Fernandes, Paula Cristina
author_role author
author2 Meireles, Daniel
Magalhães, Mariana
Gonçalves, Sara
Ribeiro Fernandes, Sofia
Fernandes, Paula Cristina
author2_role author
author
author
author
author
dc.contributor.none.fl_str_mv Repositório Científico do Centro Hospitalar Universitário de Santo António
dc.contributor.author.fl_str_mv Maciel, Juliana
Meireles, Daniel
Magalhães, Mariana
Gonçalves, Sara
Ribeiro Fernandes, Sofia
Fernandes, Paula Cristina
dc.subject.por.fl_str_mv Coronary artery ectasia
sudden infant death syndrome
Kawasaki Disease
Infant
topic Coronary artery ectasia
sudden infant death syndrome
Kawasaki Disease
Infant
description Introduction: Kawasaki disease, an acute self-limited vasculitis of small and medium arteries of unknown etiology, is the leading cause of heart disease in children in most developed countries. If untreated, it can lead to coronary artery dilatation and aneurysm, placing patients at risk for coronary thrombosis, myocardial infarction, or sudden death. Case Report: A previously healthy five-month-old boy presented with a history of respiratory symptoms and fever, being admitted for respiratory syncytial virus bronchiolitis. He maintained fever for five days associated with progressive clinical worsening and sequential development of conjunctival injection, cracked lips, swelling of hands and feet, and polymorphous rash of the limbs. Diagnostic procedures showed increased levels of inflammatory markers, hyponatremia, hypoalbuminemia, sterile pyuria, and aseptic meningitis. Despite an initial normal echocardiogram, Kawasaki disease was suspected and the boy started intravenous immunoglobulin on the fifth day. On the seventh day, echocardiogram showed signs of pancarditis and mild coronary artery ectasia and acetylsalicylic acid was started. The boy was discharged, but eight days later echocardiogram revealed major and diffuse coronary artery ectasia in a follow-up consultation and he was readmitted to start corticosteroid therapy. After five months, the boy displayed normalization of cardiac changes, without further complications. Comments: Kawasaki disease below six months of age is rare and associated with a high risk of coronary artery aneurysm. It is important to recognize the clinical and laboratory criteria associated with this entity and start early treatment, avoiding cardiac complications.
publishDate 2021
dc.date.none.fl_str_mv 2021-11-04T09:42:23Z
2021-06
2021-06-01T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10400.16/2526
url http://hdl.handle.net/10400.16/2526
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Maciel J, Meireles D, Magalhães M, Gonçalves S, Ribeiro-Fernandes S, Fernandes PC, Nascer e Crescer - Birth and Growth Medical Journal 2021;30(2): 109-113. doi:10.25753/BirthGrowthMJ.v30.i2.19077
2183-9417
10.25753/BirthGrowthMJ.v30.i2.19077
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Centro Hospitalar Universitário do Porto
publisher.none.fl_str_mv Centro Hospitalar Universitário do Porto
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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