Manure as a Potential Hotspot for Antibiotic Resistance Dissemination by Horizontal Gene Transfer Events
Autor(a) principal: | |
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Data de Publicação: | 2020 |
Outros Autores: | , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10316/106764 https://doi.org/10.3390/vetsci7030110 |
Resumo: | The increasing demand for animal-derived foods has led to intensive and large-scale livestock production with the consequent formation of large amounts of manure. Livestock manure is widely used in agricultural practices as soil fertilizer worldwide. However, several antibiotic residues, antibiotic resistance genes (ARGs) and antibiotic-resistant bacteria are frequently detected in manure and manure-amended soils. This review explores the role of manure in the persistence and dissemination of ARGs in the environment, analyzes the procedures used to decrease antimicrobial resistance in manure and the potential impact of manure application in public health. We highlight that manure shows unique features as a hotspot for antimicrobial gene dissemination by horizontal transfer events: richness in nutrients, a high abundance and diversity of bacteria populations and antibiotic residues that may exert a selective pressure on bacteria and trigger gene mobilization; reduction methodologies are able to reduce the concentrations of some, but not all, antimicrobials and microorganisms. Conjugation events are often seen in the manure environment, even after composting. Antibiotic resistance is considered a growing threat to human, animal and environmental health. Therefore, it is crucial to reduce the amount of antimicrobials and the load of antimicrobial resistant bacteria that end up in soil. |
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Manure as a Potential Hotspot for Antibiotic Resistance Dissemination by Horizontal Gene Transfer Eventsmanuresoil fertilizationhorizontal gene transferantimicrobial resistancemobile genetic elementsOne HealthThe increasing demand for animal-derived foods has led to intensive and large-scale livestock production with the consequent formation of large amounts of manure. Livestock manure is widely used in agricultural practices as soil fertilizer worldwide. However, several antibiotic residues, antibiotic resistance genes (ARGs) and antibiotic-resistant bacteria are frequently detected in manure and manure-amended soils. This review explores the role of manure in the persistence and dissemination of ARGs in the environment, analyzes the procedures used to decrease antimicrobial resistance in manure and the potential impact of manure application in public health. We highlight that manure shows unique features as a hotspot for antimicrobial gene dissemination by horizontal transfer events: richness in nutrients, a high abundance and diversity of bacteria populations and antibiotic residues that may exert a selective pressure on bacteria and trigger gene mobilization; reduction methodologies are able to reduce the concentrations of some, but not all, antimicrobials and microorganisms. Conjugation events are often seen in the manure environment, even after composting. Antibiotic resistance is considered a growing threat to human, animal and environmental health. Therefore, it is crucial to reduce the amount of antimicrobials and the load of antimicrobial resistant bacteria that end up in soil.MDPI2020-08-13info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttp://hdl.handle.net/10316/106764http://hdl.handle.net/10316/106764https://doi.org/10.3390/vetsci7030110eng2306-7381Lima, TiagoDomingues, SaraSilva, Gabriela Jorge dainfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-04-21T08:24:24Zoai:estudogeral.uc.pt:10316/106764Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T21:23:10.159945Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Manure as a Potential Hotspot for Antibiotic Resistance Dissemination by Horizontal Gene Transfer Events |
title |
Manure as a Potential Hotspot for Antibiotic Resistance Dissemination by Horizontal Gene Transfer Events |
spellingShingle |
Manure as a Potential Hotspot for Antibiotic Resistance Dissemination by Horizontal Gene Transfer Events Lima, Tiago manure soil fertilization horizontal gene transfer antimicrobial resistance mobile genetic elements One Health |
title_short |
Manure as a Potential Hotspot for Antibiotic Resistance Dissemination by Horizontal Gene Transfer Events |
title_full |
Manure as a Potential Hotspot for Antibiotic Resistance Dissemination by Horizontal Gene Transfer Events |
title_fullStr |
Manure as a Potential Hotspot for Antibiotic Resistance Dissemination by Horizontal Gene Transfer Events |
title_full_unstemmed |
Manure as a Potential Hotspot for Antibiotic Resistance Dissemination by Horizontal Gene Transfer Events |
title_sort |
Manure as a Potential Hotspot for Antibiotic Resistance Dissemination by Horizontal Gene Transfer Events |
author |
Lima, Tiago |
author_facet |
Lima, Tiago Domingues, Sara Silva, Gabriela Jorge da |
author_role |
author |
author2 |
Domingues, Sara Silva, Gabriela Jorge da |
author2_role |
author author |
dc.contributor.author.fl_str_mv |
Lima, Tiago Domingues, Sara Silva, Gabriela Jorge da |
dc.subject.por.fl_str_mv |
manure soil fertilization horizontal gene transfer antimicrobial resistance mobile genetic elements One Health |
topic |
manure soil fertilization horizontal gene transfer antimicrobial resistance mobile genetic elements One Health |
description |
The increasing demand for animal-derived foods has led to intensive and large-scale livestock production with the consequent formation of large amounts of manure. Livestock manure is widely used in agricultural practices as soil fertilizer worldwide. However, several antibiotic residues, antibiotic resistance genes (ARGs) and antibiotic-resistant bacteria are frequently detected in manure and manure-amended soils. This review explores the role of manure in the persistence and dissemination of ARGs in the environment, analyzes the procedures used to decrease antimicrobial resistance in manure and the potential impact of manure application in public health. We highlight that manure shows unique features as a hotspot for antimicrobial gene dissemination by horizontal transfer events: richness in nutrients, a high abundance and diversity of bacteria populations and antibiotic residues that may exert a selective pressure on bacteria and trigger gene mobilization; reduction methodologies are able to reduce the concentrations of some, but not all, antimicrobials and microorganisms. Conjugation events are often seen in the manure environment, even after composting. Antibiotic resistance is considered a growing threat to human, animal and environmental health. Therefore, it is crucial to reduce the amount of antimicrobials and the load of antimicrobial resistant bacteria that end up in soil. |
publishDate |
2020 |
dc.date.none.fl_str_mv |
2020-08-13 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10316/106764 http://hdl.handle.net/10316/106764 https://doi.org/10.3390/vetsci7030110 |
url |
http://hdl.handle.net/10316/106764 https://doi.org/10.3390/vetsci7030110 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
2306-7381 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.publisher.none.fl_str_mv |
MDPI |
publisher.none.fl_str_mv |
MDPI |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
instname_str |
Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
instacron_str |
RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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1799134119472398336 |