Underrated Staphylococcus species and their role in antimicrobial resistance spreading

Detalhes bibliográficos
Autor(a) principal: Rossi,Ciro César
Data de Publicação: 2020
Outros Autores: Pereira,Monalessa Fábia, Giambiagi-deMarval,Marcia
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Genetics and Molecular Biology
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572020000300303
Resumo: Abstract The increasing threat of antimicrobial resistance has shed light on the interconnection between humans, animals, the environment, and their roles in the exchange and spreading of resistance genes. In this review, we present evidences that show that Staphylococcus species, usually referred to as harmless or opportunistic pathogens, represent a threat to human and animal health for acting as reservoirs of antimicrobial resistance genes. The capacity of genetic exchange between isolates of different sources and species of the Staphylococcus genus is discussed with emphasis on mobile genetic elements, the contribution of biofilm formation, and evidences obtained either experimentally or through genome analyses. We also discuss the involvement of CRISPR-Cas systems in the limitation of horizontal gene transfer and its suitability as a molecular clock to describe the history of genetic exchange between staphylococci.
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spelling Underrated Staphylococcus species and their role in antimicrobial resistance spreadingHorizontal gene transferantimicrobial resistancecoagulase negative staphylococcusbiofilmCRISPROne HealthAbstract The increasing threat of antimicrobial resistance has shed light on the interconnection between humans, animals, the environment, and their roles in the exchange and spreading of resistance genes. In this review, we present evidences that show that Staphylococcus species, usually referred to as harmless or opportunistic pathogens, represent a threat to human and animal health for acting as reservoirs of antimicrobial resistance genes. The capacity of genetic exchange between isolates of different sources and species of the Staphylococcus genus is discussed with emphasis on mobile genetic elements, the contribution of biofilm formation, and evidences obtained either experimentally or through genome analyses. We also discuss the involvement of CRISPR-Cas systems in the limitation of horizontal gene transfer and its suitability as a molecular clock to describe the history of genetic exchange between staphylococci.Sociedade Brasileira de Genética2020-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572020000300303Genetics and Molecular Biology v.43 n.1 suppl.2 2020reponame:Genetics and Molecular Biologyinstname:Sociedade Brasileira de Genética (SBG)instacron:SBG10.1590/1678-4685-gmb-2019-0065info:eu-repo/semantics/openAccessRossi,Ciro CésarPereira,Monalessa FábiaGiambiagi-deMarval,Marciaeng2020-02-07T00:00:00Zoai:scielo:S1415-47572020000300303Revistahttp://www.gmb.org.br/ONGhttps://old.scielo.br/oai/scielo-oai.php||editor@gmb.org.br1678-46851415-4757opendoar:2020-02-07T00:00Genetics and Molecular Biology - Sociedade Brasileira de Genética (SBG)false
dc.title.none.fl_str_mv Underrated Staphylococcus species and their role in antimicrobial resistance spreading
title Underrated Staphylococcus species and their role in antimicrobial resistance spreading
spellingShingle Underrated Staphylococcus species and their role in antimicrobial resistance spreading
Rossi,Ciro César
Horizontal gene transfer
antimicrobial resistance
coagulase negative staphylococcus
biofilm
CRISPR
One Health
title_short Underrated Staphylococcus species and their role in antimicrobial resistance spreading
title_full Underrated Staphylococcus species and their role in antimicrobial resistance spreading
title_fullStr Underrated Staphylococcus species and their role in antimicrobial resistance spreading
title_full_unstemmed Underrated Staphylococcus species and their role in antimicrobial resistance spreading
title_sort Underrated Staphylococcus species and their role in antimicrobial resistance spreading
author Rossi,Ciro César
author_facet Rossi,Ciro César
Pereira,Monalessa Fábia
Giambiagi-deMarval,Marcia
author_role author
author2 Pereira,Monalessa Fábia
Giambiagi-deMarval,Marcia
author2_role author
author
dc.contributor.author.fl_str_mv Rossi,Ciro César
Pereira,Monalessa Fábia
Giambiagi-deMarval,Marcia
dc.subject.por.fl_str_mv Horizontal gene transfer
antimicrobial resistance
coagulase negative staphylococcus
biofilm
CRISPR
One Health
topic Horizontal gene transfer
antimicrobial resistance
coagulase negative staphylococcus
biofilm
CRISPR
One Health
description Abstract The increasing threat of antimicrobial resistance has shed light on the interconnection between humans, animals, the environment, and their roles in the exchange and spreading of resistance genes. In this review, we present evidences that show that Staphylococcus species, usually referred to as harmless or opportunistic pathogens, represent a threat to human and animal health for acting as reservoirs of antimicrobial resistance genes. The capacity of genetic exchange between isolates of different sources and species of the Staphylococcus genus is discussed with emphasis on mobile genetic elements, the contribution of biofilm formation, and evidences obtained either experimentally or through genome analyses. We also discuss the involvement of CRISPR-Cas systems in the limitation of horizontal gene transfer and its suitability as a molecular clock to describe the history of genetic exchange between staphylococci.
publishDate 2020
dc.date.none.fl_str_mv 2020-01-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572020000300303
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572020000300303
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/1678-4685-gmb-2019-0065
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Genética
publisher.none.fl_str_mv Sociedade Brasileira de Genética
dc.source.none.fl_str_mv Genetics and Molecular Biology v.43 n.1 suppl.2 2020
reponame:Genetics and Molecular Biology
instname:Sociedade Brasileira de Genética (SBG)
instacron:SBG
instname_str Sociedade Brasileira de Genética (SBG)
instacron_str SBG
institution SBG
reponame_str Genetics and Molecular Biology
collection Genetics and Molecular Biology
repository.name.fl_str_mv Genetics and Molecular Biology - Sociedade Brasileira de Genética (SBG)
repository.mail.fl_str_mv ||editor@gmb.org.br
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