Antioxidant Activity and Cytotoxicity of Taraxacum hispanicum Aqueous and Ethanolic Extracts on HepG2 Cells

Detalhes bibliográficos
Autor(a) principal: Laranjeira, C.
Data de Publicação: 2017
Outros Autores: Nogueira, A., Almeida, R., Oliveira, Ana, Ferraz Oliveira, Rita, Pinho, Cláudia, Cruz, Agostinho
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10400.22/16821
Resumo: Plants belonging to the genus Taraxacum have been used in traditional medicine. Nowadays, extracts of these plants have been reported for the treatment of diseases, including liver disorders. Increasing interest and research on these plants also revealed its potential for treating cancer. This study aims to evaluate the antioxidant activity and cytotoxic properties of crude extracts from aerial parts of Taraxacum hispanicum H.Lindb, against human hepatocarcinoma (HepG2). Material and methods: Evaluation of the antioxidant properties was performed using DPPH in vitro test, superoxide scavenging assay and Fe2+ chelating activity. MTT assay was used to determine metabolic activity, for 24 and 48 hours.
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spelling Antioxidant Activity and Cytotoxicity of Taraxacum hispanicum Aqueous and Ethanolic Extracts on HepG2 CellsAntioxidantCytotoxicityHepG2 cellsTaraxacum hispanicumPlants belonging to the genus Taraxacum have been used in traditional medicine. Nowadays, extracts of these plants have been reported for the treatment of diseases, including liver disorders. Increasing interest and research on these plants also revealed its potential for treating cancer. This study aims to evaluate the antioxidant activity and cytotoxic properties of crude extracts from aerial parts of Taraxacum hispanicum H.Lindb, against human hepatocarcinoma (HepG2). Material and methods: Evaluation of the antioxidant properties was performed using DPPH in vitro test, superoxide scavenging assay and Fe2+ chelating activity. MTT assay was used to determine metabolic activity, for 24 and 48 hours.International Journal of Pharmacognosy and Phytochemical ResearchRepositório Científico do Instituto Politécnico do PortoLaranjeira, C.Nogueira, A.Almeida, R.Oliveira, AnaFerraz Oliveira, RitaPinho, CláudiaCruz, Agostinho2021-02-02T09:42:32Z20172017-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.22/16821engC, L., A, N., Almeida da Silva, R., Oliveira, A., F, O., Pinho, C., & Cruz, A. (2017). Antioxidant Activity and Cytotoxicity of Taraxacum hispanicum Aqueous and Ethanolic Extracts on HepG2 Cells. International Journal of Pharmacognosy and Phytochemical Research, 9. doi:10.25258/ijpapr.v9i1.803110.25258/ijpapr.v9i1.8031info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-03-13T13:04:31Zoai:recipp.ipp.pt:10400.22/16821Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T17:36:27.821122Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Antioxidant Activity and Cytotoxicity of Taraxacum hispanicum Aqueous and Ethanolic Extracts on HepG2 Cells
title Antioxidant Activity and Cytotoxicity of Taraxacum hispanicum Aqueous and Ethanolic Extracts on HepG2 Cells
spellingShingle Antioxidant Activity and Cytotoxicity of Taraxacum hispanicum Aqueous and Ethanolic Extracts on HepG2 Cells
Laranjeira, C.
Antioxidant
Cytotoxicity
HepG2 cells
Taraxacum hispanicum
title_short Antioxidant Activity and Cytotoxicity of Taraxacum hispanicum Aqueous and Ethanolic Extracts on HepG2 Cells
title_full Antioxidant Activity and Cytotoxicity of Taraxacum hispanicum Aqueous and Ethanolic Extracts on HepG2 Cells
title_fullStr Antioxidant Activity and Cytotoxicity of Taraxacum hispanicum Aqueous and Ethanolic Extracts on HepG2 Cells
title_full_unstemmed Antioxidant Activity and Cytotoxicity of Taraxacum hispanicum Aqueous and Ethanolic Extracts on HepG2 Cells
title_sort Antioxidant Activity and Cytotoxicity of Taraxacum hispanicum Aqueous and Ethanolic Extracts on HepG2 Cells
author Laranjeira, C.
author_facet Laranjeira, C.
Nogueira, A.
Almeida, R.
Oliveira, Ana
Ferraz Oliveira, Rita
Pinho, Cláudia
Cruz, Agostinho
author_role author
author2 Nogueira, A.
Almeida, R.
Oliveira, Ana
Ferraz Oliveira, Rita
Pinho, Cláudia
Cruz, Agostinho
author2_role author
author
author
author
author
author
dc.contributor.none.fl_str_mv Repositório Científico do Instituto Politécnico do Porto
dc.contributor.author.fl_str_mv Laranjeira, C.
Nogueira, A.
Almeida, R.
Oliveira, Ana
Ferraz Oliveira, Rita
Pinho, Cláudia
Cruz, Agostinho
dc.subject.por.fl_str_mv Antioxidant
Cytotoxicity
HepG2 cells
Taraxacum hispanicum
topic Antioxidant
Cytotoxicity
HepG2 cells
Taraxacum hispanicum
description Plants belonging to the genus Taraxacum have been used in traditional medicine. Nowadays, extracts of these plants have been reported for the treatment of diseases, including liver disorders. Increasing interest and research on these plants also revealed its potential for treating cancer. This study aims to evaluate the antioxidant activity and cytotoxic properties of crude extracts from aerial parts of Taraxacum hispanicum H.Lindb, against human hepatocarcinoma (HepG2). Material and methods: Evaluation of the antioxidant properties was performed using DPPH in vitro test, superoxide scavenging assay and Fe2+ chelating activity. MTT assay was used to determine metabolic activity, for 24 and 48 hours.
publishDate 2017
dc.date.none.fl_str_mv 2017
2017-01-01T00:00:00Z
2021-02-02T09:42:32Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10400.22/16821
url http://hdl.handle.net/10400.22/16821
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv C, L., A, N., Almeida da Silva, R., Oliveira, A., F, O., Pinho, C., & Cruz, A. (2017). Antioxidant Activity and Cytotoxicity of Taraxacum hispanicum Aqueous and Ethanolic Extracts on HepG2 Cells. International Journal of Pharmacognosy and Phytochemical Research, 9. doi:10.25258/ijpapr.v9i1.8031
10.25258/ijpapr.v9i1.8031
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv International Journal of Pharmacognosy and Phytochemical Research
publisher.none.fl_str_mv International Journal of Pharmacognosy and Phytochemical Research
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
repository.mail.fl_str_mv
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