Effect of film thickness in gelatin hybrid gels for artificial olfaction
Autor(a) principal: | |
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Data de Publicação: | 2019 |
Outros Autores: | , , , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10362/141508 |
Resumo: | Pest-OE/AGR/UI0245/2013 SCENT-ERC-2014-STG-639123 CapTherPV-ERC-2014-CoG-647596 POCI-01-0145-FEDER-007728 |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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7160 |
spelling |
Effect of film thickness in gelatin hybrid gels for artificial olfactionElectronic noseGas sensorGelatinIonic liquidLiquid crystalMachine learningBiomaterialsBiomedical EngineeringCell BiologyMolecular BiologyBioengineeringBiotechnologyPest-OE/AGR/UI0245/2013 SCENT-ERC-2014-STG-639123 CapTherPV-ERC-2014-CoG-647596 POCI-01-0145-FEDER-007728Artificial olfaction is a fast-growing field aiming to mimic natural olfactory systems. Olfactory systems rely on a first step of molecular recognition in which volatile organic compounds (VOCs) bind to an array of specialized olfactory proteins. This results in electrical signals transduced to the brain where pattern recognition is performed. An efficient approach in artificial olfaction combines gas-sensitive materials with dedicated signal processing and classification tools. In this work, films of gelatin hybrid gels with a single composition that change their optical properties upon binding to VOCs were studied as gas-sensing materials in a custom-built electronic nose. The effect of films thickness was studied by acquiring signals from gelatin hybrid gel films with thicknesses between 15 and 90 μm when exposed to 11 distinct VOCs. Several features were extracted from the signals obtained and then used to implement a dedicated automatic classifier based on support vector machines for data processing. As an optical signature could be associated to each VOC, the developed algorithms classified 11 distinct VOCs with high accuracy and precision (higher than 98%), in particular when using optical signals from a single film composition with 30 μm thickness. This shows an unprecedented example of soft matter in artificial olfaction, in which a single gelatin hybrid gel, and not an array of sensing materials, can provide enough information to accurately classify VOCs with small structural and functional differences.UCIBIO - Applied Molecular Biosciences UnitDQ - Departamento de QuímicaLIBPhys-UNLDF – Departamento de FísicaCENIMAT-i3N - Centro de Investigação de Materiais (Lab. Associado I3N)DCM - Departamento de Ciência dos MateriaisRUNEsteves, CarinaSantos, Gonçalo M. C.Alves, CláudiaPalma, Susana I. C. J.Porteira, Ana R.Filho, JoãoCosta, Henrique M. A.Alves, Vitor D.Morais Faustino, Bruno M.Ferreira, IsabelGamboa, HugoRoque, Ana C. A.2022-07-06T22:22:06Z2019-01-012019-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10362/141508eng2590-0064PURE: 16698294https://doi.org/10.1016/j.mtbio.2019.100002info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-03-11T05:18:55Zoai:run.unl.pt:10362/141508Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T03:50:01.409880Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Effect of film thickness in gelatin hybrid gels for artificial olfaction |
title |
Effect of film thickness in gelatin hybrid gels for artificial olfaction |
spellingShingle |
Effect of film thickness in gelatin hybrid gels for artificial olfaction Esteves, Carina Electronic nose Gas sensor Gelatin Ionic liquid Liquid crystal Machine learning Biomaterials Biomedical Engineering Cell Biology Molecular Biology Bioengineering Biotechnology |
title_short |
Effect of film thickness in gelatin hybrid gels for artificial olfaction |
title_full |
Effect of film thickness in gelatin hybrid gels for artificial olfaction |
title_fullStr |
Effect of film thickness in gelatin hybrid gels for artificial olfaction |
title_full_unstemmed |
Effect of film thickness in gelatin hybrid gels for artificial olfaction |
title_sort |
Effect of film thickness in gelatin hybrid gels for artificial olfaction |
author |
Esteves, Carina |
author_facet |
Esteves, Carina Santos, Gonçalo M. C. Alves, Cláudia Palma, Susana I. C. J. Porteira, Ana R. Filho, João Costa, Henrique M. A. Alves, Vitor D. Morais Faustino, Bruno M. Ferreira, Isabel Gamboa, Hugo Roque, Ana C. A. |
author_role |
author |
author2 |
Santos, Gonçalo M. C. Alves, Cláudia Palma, Susana I. C. J. Porteira, Ana R. Filho, João Costa, Henrique M. A. Alves, Vitor D. Morais Faustino, Bruno M. Ferreira, Isabel Gamboa, Hugo Roque, Ana C. A. |
author2_role |
author author author author author author author author author author author |
dc.contributor.none.fl_str_mv |
UCIBIO - Applied Molecular Biosciences Unit DQ - Departamento de Química LIBPhys-UNL DF – Departamento de Física CENIMAT-i3N - Centro de Investigação de Materiais (Lab. Associado I3N) DCM - Departamento de Ciência dos Materiais RUN |
dc.contributor.author.fl_str_mv |
Esteves, Carina Santos, Gonçalo M. C. Alves, Cláudia Palma, Susana I. C. J. Porteira, Ana R. Filho, João Costa, Henrique M. A. Alves, Vitor D. Morais Faustino, Bruno M. Ferreira, Isabel Gamboa, Hugo Roque, Ana C. A. |
dc.subject.por.fl_str_mv |
Electronic nose Gas sensor Gelatin Ionic liquid Liquid crystal Machine learning Biomaterials Biomedical Engineering Cell Biology Molecular Biology Bioengineering Biotechnology |
topic |
Electronic nose Gas sensor Gelatin Ionic liquid Liquid crystal Machine learning Biomaterials Biomedical Engineering Cell Biology Molecular Biology Bioengineering Biotechnology |
description |
Pest-OE/AGR/UI0245/2013 SCENT-ERC-2014-STG-639123 CapTherPV-ERC-2014-CoG-647596 POCI-01-0145-FEDER-007728 |
publishDate |
2019 |
dc.date.none.fl_str_mv |
2019-01-01 2019-01-01T00:00:00Z 2022-07-06T22:22:06Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10362/141508 |
url |
http://hdl.handle.net/10362/141508 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
2590-0064 PURE: 16698294 https://doi.org/10.1016/j.mtbio.2019.100002 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
instname_str |
Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
instacron_str |
RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
repository.mail.fl_str_mv |
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1799138097928077312 |