Quality of life in pediatric asthma patients and their parents: A meta-analysis on 20 years of research
Autor(a) principal: | |
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Data de Publicação: | 2015 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10316/45410 https://doi.org/10.1586/14737167.2015.1008459 |
Resumo: | Introduction. This meta-analytic review was conducted to estimate the magnitude of quality of life (QoL) impairments in children/adolescents with asthma and their parents. Method. A systematic search in four electronic databases revealed 15 quantitative studies published between 1994-2013 that directly compared the QoL of 7- to 18-year-old asthma patients/parents to community/healthy controls. Pooled mean differences (MD) with 95% CI were estimated using the inverse-variance random-effects method. Results. Pediatric asthma patients (n = 1,797) presented lower overall QoL (MD = -7.48, CI = -10.67/ -4.29), physical functioning (MD = -9.36, CI = -11.85/ -6.86), psychological functioning (MD = -5.00, CI = -7.17/ -2.82), and social functioning (MD = -3.76, CI = -5.80/ -1.72), compared to controls (n = 13,266). For parents (666 cases and 7,328 controls), asthma was associated with lower physical functioning (MD = -10.15, CI = -12.21/ -8.08). Between-studies heterogeneity was explained by type of informant and selection of controls. Conclusion. The ascertainment of the magnitude of QoL impairments and the most affected QoL dimensions for pediatric asthma patients/parents may contribute to the outlining of realistic goals for multidisciplinary interventions in healthcare settings and evaluate its cost-effectiveness. |
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Quality of life in pediatric asthma patients and their parents: A meta-analysis on 20 years of researchQuality of LifeChildren and adolescentsAsthmaMeta-analysisParents• Parents • Patient- and parent-reported outcomesIntroduction. This meta-analytic review was conducted to estimate the magnitude of quality of life (QoL) impairments in children/adolescents with asthma and their parents. Method. A systematic search in four electronic databases revealed 15 quantitative studies published between 1994-2013 that directly compared the QoL of 7- to 18-year-old asthma patients/parents to community/healthy controls. Pooled mean differences (MD) with 95% CI were estimated using the inverse-variance random-effects method. Results. Pediatric asthma patients (n = 1,797) presented lower overall QoL (MD = -7.48, CI = -10.67/ -4.29), physical functioning (MD = -9.36, CI = -11.85/ -6.86), psychological functioning (MD = -5.00, CI = -7.17/ -2.82), and social functioning (MD = -3.76, CI = -5.80/ -1.72), compared to controls (n = 13,266). For parents (666 cases and 7,328 controls), asthma was associated with lower physical functioning (MD = -10.15, CI = -12.21/ -8.08). Between-studies heterogeneity was explained by type of informant and selection of controls. Conclusion. The ascertainment of the magnitude of QoL impairments and the most affected QoL dimensions for pediatric asthma patients/parents may contribute to the outlining of realistic goals for multidisciplinary interventions in healthcare settings and evaluate its cost-effectiveness.This study was supported by the Relationships, Development & Health Research Group of the R&D Unit Cognitive-Behavioral Center for Research and Intervention (PEst-OE/PSI/UI0730/2014) and by a PhD Scholarship from the Portuguese Foundation for Science and Technology (SFRH/BD/69885/2010). The authors have no other relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript apart from those disclosed.2015info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttp://hdl.handle.net/10316/45410http://hdl.handle.net/10316/45410https://doi.org/10.1586/14737167.2015.1008459engSilva, N., Carona, C., Crespo, C., & Canavarro, M. C. (2015). Quality of life in pediatric asthma patients and their parents: A meta-analysis on 20 years of research. Expert Review of Pharmacoeconomics & Outcomes Research, 15(3), 499-519. doi:10.1586/14737167.2015.1008459http://www.tandfonline.com/doi/abs/10.1586/14737167.2015.1008459?journalCode=ierp20Silva, NeuzaCarona, CarlosCrespo, CarlaCanavarro, Maria Cristinainfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2021-06-29T10:03:34Zoai:estudogeral.uc.pt:10316/45410Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T20:48:31.069958Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Quality of life in pediatric asthma patients and their parents: A meta-analysis on 20 years of research |
title |
Quality of life in pediatric asthma patients and their parents: A meta-analysis on 20 years of research |
spellingShingle |
Quality of life in pediatric asthma patients and their parents: A meta-analysis on 20 years of research Silva, Neuza Quality of Life Children and adolescents Asthma Meta-analysis Parents • Parents • Patient- and parent-reported outcomes |
title_short |
Quality of life in pediatric asthma patients and their parents: A meta-analysis on 20 years of research |
title_full |
Quality of life in pediatric asthma patients and their parents: A meta-analysis on 20 years of research |
title_fullStr |
Quality of life in pediatric asthma patients and their parents: A meta-analysis on 20 years of research |
title_full_unstemmed |
Quality of life in pediatric asthma patients and their parents: A meta-analysis on 20 years of research |
title_sort |
Quality of life in pediatric asthma patients and their parents: A meta-analysis on 20 years of research |
author |
Silva, Neuza |
author_facet |
Silva, Neuza Carona, Carlos Crespo, Carla Canavarro, Maria Cristina |
author_role |
author |
author2 |
Carona, Carlos Crespo, Carla Canavarro, Maria Cristina |
author2_role |
author author author |
dc.contributor.author.fl_str_mv |
Silva, Neuza Carona, Carlos Crespo, Carla Canavarro, Maria Cristina |
dc.subject.por.fl_str_mv |
Quality of Life Children and adolescents Asthma Meta-analysis Parents • Parents • Patient- and parent-reported outcomes |
topic |
Quality of Life Children and adolescents Asthma Meta-analysis Parents • Parents • Patient- and parent-reported outcomes |
description |
Introduction. This meta-analytic review was conducted to estimate the magnitude of quality of life (QoL) impairments in children/adolescents with asthma and their parents. Method. A systematic search in four electronic databases revealed 15 quantitative studies published between 1994-2013 that directly compared the QoL of 7- to 18-year-old asthma patients/parents to community/healthy controls. Pooled mean differences (MD) with 95% CI were estimated using the inverse-variance random-effects method. Results. Pediatric asthma patients (n = 1,797) presented lower overall QoL (MD = -7.48, CI = -10.67/ -4.29), physical functioning (MD = -9.36, CI = -11.85/ -6.86), psychological functioning (MD = -5.00, CI = -7.17/ -2.82), and social functioning (MD = -3.76, CI = -5.80/ -1.72), compared to controls (n = 13,266). For parents (666 cases and 7,328 controls), asthma was associated with lower physical functioning (MD = -10.15, CI = -12.21/ -8.08). Between-studies heterogeneity was explained by type of informant and selection of controls. Conclusion. The ascertainment of the magnitude of QoL impairments and the most affected QoL dimensions for pediatric asthma patients/parents may contribute to the outlining of realistic goals for multidisciplinary interventions in healthcare settings and evaluate its cost-effectiveness. |
publishDate |
2015 |
dc.date.none.fl_str_mv |
2015 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10316/45410 http://hdl.handle.net/10316/45410 https://doi.org/10.1586/14737167.2015.1008459 |
url |
http://hdl.handle.net/10316/45410 https://doi.org/10.1586/14737167.2015.1008459 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Silva, N., Carona, C., Crespo, C., & Canavarro, M. C. (2015). Quality of life in pediatric asthma patients and their parents: A meta-analysis on 20 years of research. Expert Review of Pharmacoeconomics & Outcomes Research, 15(3), 499-519. doi:10.1586/14737167.2015.1008459 http://www.tandfonline.com/doi/abs/10.1586/14737167.2015.1008459?journalCode=ierp20 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
instacron_str |
RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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