Whipple disease and central nervous system.

Detalhes bibliográficos
Autor(a) principal: Abreu, Pedro
Data de Publicação: 2005
Outros Autores: Azevedo, Elsa, Lobo, Luís, Moura, Conceição Souto, Pontes, Celso
Tipo de documento: Artigo
Idioma: por
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/1023
Resumo: Whipple disease (WD) is a rare systemic infection caused by the bacteria Tropheryma whipplei. Slowly progressive dementia, supranuclear ophthalmoplegia, headache, myoclonus, hypothalamic dysfunction, oculomasticatory-skeletal myorythmia are characteristic manifestations when WD involves the central nervous system (CNS). Treatment of cerebral WD should be performed with antibiotics that reach the CNS for at the least one-year. We alert for the early diagnosis of WD in patients with exclusively neurological clinical pictures, sometimes with atypical or non-definitive diagnosis, because it is a potential treatable disease.
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spelling Whipple disease and central nervous system.Doença de Whipple e sistema nervoso central.Whipple disease (WD) is a rare systemic infection caused by the bacteria Tropheryma whipplei. Slowly progressive dementia, supranuclear ophthalmoplegia, headache, myoclonus, hypothalamic dysfunction, oculomasticatory-skeletal myorythmia are characteristic manifestations when WD involves the central nervous system (CNS). Treatment of cerebral WD should be performed with antibiotics that reach the CNS for at the least one-year. We alert for the early diagnosis of WD in patients with exclusively neurological clinical pictures, sometimes with atypical or non-definitive diagnosis, because it is a potential treatable disease.Whipple disease (WD) is a rare systemic infection caused by the bacteria Tropheryma whipplei. Slowly progressive dementia, supranuclear ophthalmoplegia, headache, myoclonus, hypothalamic dysfunction, oculomasticatory-skeletal myorythmia are characteristic manifestations when WD involves the central nervous system (CNS). Treatment of cerebral WD should be performed with antibiotics that reach the CNS for at the least one-year. We alert for the early diagnosis of WD in patients with exclusively neurological clinical pictures, sometimes with atypical or non-definitive diagnosis, because it is a potential treatable disease.Ordem dos Médicos2005-06-30info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttps://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/1023oai:ojs.www.actamedicaportuguesa.com:article/1023Acta Médica Portuguesa; Vol. 18 No. 3 (2005): May-June; 199-208Acta Médica Portuguesa; Vol. 18 N.º 3 (2005): Maio-Junho; 199-2081646-07580870-399Xreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAPporhttps://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/1023https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/1023/691Abreu, PedroAzevedo, ElsaLobo, LuísMoura, Conceição SoutoPontes, Celsoinfo:eu-repo/semantics/openAccess2022-12-20T10:57:20Zoai:ojs.www.actamedicaportuguesa.com:article/1023Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T16:16:55.030828Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Whipple disease and central nervous system.
Doença de Whipple e sistema nervoso central.
title Whipple disease and central nervous system.
spellingShingle Whipple disease and central nervous system.
Abreu, Pedro
title_short Whipple disease and central nervous system.
title_full Whipple disease and central nervous system.
title_fullStr Whipple disease and central nervous system.
title_full_unstemmed Whipple disease and central nervous system.
title_sort Whipple disease and central nervous system.
author Abreu, Pedro
author_facet Abreu, Pedro
Azevedo, Elsa
Lobo, Luís
Moura, Conceição Souto
Pontes, Celso
author_role author
author2 Azevedo, Elsa
Lobo, Luís
Moura, Conceição Souto
Pontes, Celso
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Abreu, Pedro
Azevedo, Elsa
Lobo, Luís
Moura, Conceição Souto
Pontes, Celso
description Whipple disease (WD) is a rare systemic infection caused by the bacteria Tropheryma whipplei. Slowly progressive dementia, supranuclear ophthalmoplegia, headache, myoclonus, hypothalamic dysfunction, oculomasticatory-skeletal myorythmia are characteristic manifestations when WD involves the central nervous system (CNS). Treatment of cerebral WD should be performed with antibiotics that reach the CNS for at the least one-year. We alert for the early diagnosis of WD in patients with exclusively neurological clinical pictures, sometimes with atypical or non-definitive diagnosis, because it is a potential treatable disease.
publishDate 2005
dc.date.none.fl_str_mv 2005-06-30
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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status_str publishedVersion
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oai:ojs.www.actamedicaportuguesa.com:article/1023
url https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/1023
identifier_str_mv oai:ojs.www.actamedicaportuguesa.com:article/1023
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/1023
https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/1023/691
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Ordem dos Médicos
publisher.none.fl_str_mv Ordem dos Médicos
dc.source.none.fl_str_mv Acta Médica Portuguesa; Vol. 18 No. 3 (2005): May-June; 199-208
Acta Médica Portuguesa; Vol. 18 N.º 3 (2005): Maio-Junho; 199-208
1646-0758
0870-399X
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
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