Automatic tracking and deformation measurements of red blood cells flowing through a microchannel with a microstenosis: the keyhole model
Autor(a) principal: | |
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Data de Publicação: | 2016 |
Outros Autores: | , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10198/16722 |
Resumo: | This study aimed to assess the motion and its deformation index (DI) of red blood cells (RBCs) flowing through a microchannel with a microstenosis using an image analysis-based method. For this purpose, a microchannel having a smooth contraction was used and the images were captured by a standard high-speed microscopy system. An automatic image-processing and analysing method was developed in a MATLAB environment to not only track the motion of RBCs but also measure the DI along the microchannel. The keyhole model, tested in this study, proved to be a promising technique to automatically track individual RBCs in microchannels. |
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Automatic tracking and deformation measurements of red blood cells flowing through a microchannel with a microstenosis: the keyhole modelAutomatic trackingDeformation indexKeyhole modelMicrofluidsRed blood cellsThis study aimed to assess the motion and its deformation index (DI) of red blood cells (RBCs) flowing through a microchannel with a microstenosis using an image analysis-based method. For this purpose, a microchannel having a smooth contraction was used and the images were captured by a standard high-speed microscopy system. An automatic image-processing and analysing method was developed in a MATLAB environment to not only track the motion of RBCs but also measure the DI along the microchannel. The keyhole model, tested in this study, proved to be a promising technique to automatically track individual RBCs in microchannels.This study was financially supported by the Science and Technology Foundation (FCT), COMPETE, QREN and the European Union (FEDER) [grant numbers PTDC/SAU-BEB/ 105650/2008, PTDC/SAU-ENB/116929/2010, EXPL/EMS-SIS/ 2215/2013]Taylor & Francis GroupBiblioteca Digital do IPBTaboada, Bruna Rafaela PereiraMonteiro, Fernando C.Lima, Rui A.2018-04-06T10:41:50Z20162016-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10198/16722engTaboada, B.; Monteiro, Fernando C.; Lima, R. (2016)- Automatic tracking and deformation measurements of red blood cells flowing through a microchannel with a microstenosis: the keyhole model. Computer Methods in Biomechanics and Biomedical Engineering: Imaging and Visualization. ISSN 2168-1163. 4:3-4, p. 229-2372168-116310.1080/21681163.2014.957868info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-11-21T10:38:15Zoai:bibliotecadigital.ipb.pt:10198/16722Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T23:06:00.910810Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Automatic tracking and deformation measurements of red blood cells flowing through a microchannel with a microstenosis: the keyhole model |
title |
Automatic tracking and deformation measurements of red blood cells flowing through a microchannel with a microstenosis: the keyhole model |
spellingShingle |
Automatic tracking and deformation measurements of red blood cells flowing through a microchannel with a microstenosis: the keyhole model Taboada, Bruna Rafaela Pereira Automatic tracking Deformation index Keyhole model Microfluids Red blood cells |
title_short |
Automatic tracking and deformation measurements of red blood cells flowing through a microchannel with a microstenosis: the keyhole model |
title_full |
Automatic tracking and deformation measurements of red blood cells flowing through a microchannel with a microstenosis: the keyhole model |
title_fullStr |
Automatic tracking and deformation measurements of red blood cells flowing through a microchannel with a microstenosis: the keyhole model |
title_full_unstemmed |
Automatic tracking and deformation measurements of red blood cells flowing through a microchannel with a microstenosis: the keyhole model |
title_sort |
Automatic tracking and deformation measurements of red blood cells flowing through a microchannel with a microstenosis: the keyhole model |
author |
Taboada, Bruna Rafaela Pereira |
author_facet |
Taboada, Bruna Rafaela Pereira Monteiro, Fernando C. Lima, Rui A. |
author_role |
author |
author2 |
Monteiro, Fernando C. Lima, Rui A. |
author2_role |
author author |
dc.contributor.none.fl_str_mv |
Biblioteca Digital do IPB |
dc.contributor.author.fl_str_mv |
Taboada, Bruna Rafaela Pereira Monteiro, Fernando C. Lima, Rui A. |
dc.subject.por.fl_str_mv |
Automatic tracking Deformation index Keyhole model Microfluids Red blood cells |
topic |
Automatic tracking Deformation index Keyhole model Microfluids Red blood cells |
description |
This study aimed to assess the motion and its deformation index (DI) of red blood cells (RBCs) flowing through a microchannel with a microstenosis using an image analysis-based method. For this purpose, a microchannel having a smooth contraction was used and the images were captured by a standard high-speed microscopy system. An automatic image-processing and analysing method was developed in a MATLAB environment to not only track the motion of RBCs but also measure the DI along the microchannel. The keyhole model, tested in this study, proved to be a promising technique to automatically track individual RBCs in microchannels. |
publishDate |
2016 |
dc.date.none.fl_str_mv |
2016 2016-01-01T00:00:00Z 2018-04-06T10:41:50Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10198/16722 |
url |
http://hdl.handle.net/10198/16722 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Taboada, B.; Monteiro, Fernando C.; Lima, R. (2016)- Automatic tracking and deformation measurements of red blood cells flowing through a microchannel with a microstenosis: the keyhole model. Computer Methods in Biomechanics and Biomedical Engineering: Imaging and Visualization. ISSN 2168-1163. 4:3-4, p. 229-237 2168-1163 10.1080/21681163.2014.957868 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Taylor & Francis Group |
publisher.none.fl_str_mv |
Taylor & Francis Group |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
instname_str |
Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
instacron_str |
RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
repository.mail.fl_str_mv |
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1799135312736157696 |