Biotechnological strategy for the exploitation of the invasive Asparagopsis armata as an underutilized natural source of bioactive compounds

Detalhes bibliográficos
Autor(a) principal: Cairrão, André
Data de Publicação: 2022
Tipo de documento: Dissertação
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10362/163135
Resumo: " Microorganism resistance to current antibiotics has increased morbidity and mortality, prompting the search for naturally occurring candidate drugs from terrestrial and marine sources. Algae can produce a wide range of bioactive secondary metabolites, some of which display biomedical potential in the treatment of human diseases. Multiple studies have shown that Asparagopsis spp. are promising sources of antimicrobial compounds. However, to date, the bioactivities of Asparagopsis aqueous extracts have never been tested against pathogenic fungi and bacteria. Additionally, this invasive species is present in several coastlines all over the world making it a sustainable, easily obtainable, natural resource. In this study, the capacity of various steam-based extraction methods to render bioactive extracts against the model microorganisms were thoroughly compared using metabolic activity (MTT) and viability (CFUs) assays.(...)"
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spelling Biotechnological strategy for the exploitation of the invasive Asparagopsis armata as an underutilized natural source of bioactive compoundsMarine resourcesAsparagopsis armataSteam distillationAntimicrobial activity" Microorganism resistance to current antibiotics has increased morbidity and mortality, prompting the search for naturally occurring candidate drugs from terrestrial and marine sources. Algae can produce a wide range of bioactive secondary metabolites, some of which display biomedical potential in the treatment of human diseases. Multiple studies have shown that Asparagopsis spp. are promising sources of antimicrobial compounds. However, to date, the bioactivities of Asparagopsis aqueous extracts have never been tested against pathogenic fungi and bacteria. Additionally, this invasive species is present in several coastlines all over the world making it a sustainable, easily obtainable, natural resource. In this study, the capacity of various steam-based extraction methods to render bioactive extracts against the model microorganisms were thoroughly compared using metabolic activity (MTT) and viability (CFUs) assays.(...)"Instituto de Tecnologia Química e Biológica António Xavier. Universidade Nova de LisboaRUNCairrão, André2022-05-012025-05-30T00:00:00Z2022-05-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/masterThesisapplication/pdfhttp://hdl.handle.net/10362/163135TID:203514769enginfo:eu-repo/semantics/embargoedAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-03-11T05:46:11Zoai:run.unl.pt:10362/163135Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T03:59:16.046544Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Biotechnological strategy for the exploitation of the invasive Asparagopsis armata as an underutilized natural source of bioactive compounds
title Biotechnological strategy for the exploitation of the invasive Asparagopsis armata as an underutilized natural source of bioactive compounds
spellingShingle Biotechnological strategy for the exploitation of the invasive Asparagopsis armata as an underutilized natural source of bioactive compounds
Cairrão, André
Marine resources
Asparagopsis armata
Steam distillation
Antimicrobial activity
title_short Biotechnological strategy for the exploitation of the invasive Asparagopsis armata as an underutilized natural source of bioactive compounds
title_full Biotechnological strategy for the exploitation of the invasive Asparagopsis armata as an underutilized natural source of bioactive compounds
title_fullStr Biotechnological strategy for the exploitation of the invasive Asparagopsis armata as an underutilized natural source of bioactive compounds
title_full_unstemmed Biotechnological strategy for the exploitation of the invasive Asparagopsis armata as an underutilized natural source of bioactive compounds
title_sort Biotechnological strategy for the exploitation of the invasive Asparagopsis armata as an underutilized natural source of bioactive compounds
author Cairrão, André
author_facet Cairrão, André
author_role author
dc.contributor.none.fl_str_mv RUN
dc.contributor.author.fl_str_mv Cairrão, André
dc.subject.por.fl_str_mv Marine resources
Asparagopsis armata
Steam distillation
Antimicrobial activity
topic Marine resources
Asparagopsis armata
Steam distillation
Antimicrobial activity
description " Microorganism resistance to current antibiotics has increased morbidity and mortality, prompting the search for naturally occurring candidate drugs from terrestrial and marine sources. Algae can produce a wide range of bioactive secondary metabolites, some of which display biomedical potential in the treatment of human diseases. Multiple studies have shown that Asparagopsis spp. are promising sources of antimicrobial compounds. However, to date, the bioactivities of Asparagopsis aqueous extracts have never been tested against pathogenic fungi and bacteria. Additionally, this invasive species is present in several coastlines all over the world making it a sustainable, easily obtainable, natural resource. In this study, the capacity of various steam-based extraction methods to render bioactive extracts against the model microorganisms were thoroughly compared using metabolic activity (MTT) and viability (CFUs) assays.(...)"
publishDate 2022
dc.date.none.fl_str_mv 2022-05-01
2022-05-01T00:00:00Z
2025-05-30T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/masterThesis
format masterThesis
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10362/163135
TID:203514769
url http://hdl.handle.net/10362/163135
identifier_str_mv TID:203514769
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/embargoedAccess
eu_rights_str_mv embargoedAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Instituto de Tecnologia Química e Biológica António Xavier. Universidade Nova de Lisboa
publisher.none.fl_str_mv Instituto de Tecnologia Química e Biológica António Xavier. Universidade Nova de Lisboa
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
repository.mail.fl_str_mv
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