Progression of Ganglion Cell-Inner Plexiform layer thickness in the initial stages of diabetic retinopathy in type 2 diabetic patients: a 5-year longitudinal study

Detalhes bibliográficos
Autor(a) principal: Tavares, Diana
Data de Publicação: 2021
Outros Autores: Madeira, Maria H., Marques, Inês P., Santos, Torcato, Santos, Ana Rita, Lobo, Conceição, Cunha-Vaz, José
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10400.22/19066
Resumo: Diabetic Retinopathy (DR)is a frequent complication of DiabetesMellitus (DM) andthe main cause of vision loss in the working population in western countries. Diabetic Retinopathy has always been considered a microvascular disease, but it has been suggested that neurodegeneration is also associated with this complex pathology[1], although there is evidence indicating that the neurodegenerative process may progress independently[2]. To evaluate this potential association, we have examined the progression of neurodegeneration over a 5-year period of follow-up (considering thinning of ganglion cell + inner plexiform retinal layers (GCL+IPL) in individuals with type 2 diabetes (T2D) and nonproliferative DR) and explored whetheritis associated with microaneurysmturnover (MAT), diseaselevel at baseline and severity progression.
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spelling Progression of Ganglion Cell-Inner Plexiform layer thickness in the initial stages of diabetic retinopathy in type 2 diabetic patients: a 5-year longitudinal studyDiabetic retinopathyMixed modelsNeurodegenerationDiabetic Retinopathy (DR)is a frequent complication of DiabetesMellitus (DM) andthe main cause of vision loss in the working population in western countries. Diabetic Retinopathy has always been considered a microvascular disease, but it has been suggested that neurodegeneration is also associated with this complex pathology[1], although there is evidence indicating that the neurodegenerative process may progress independently[2]. To evaluate this potential association, we have examined the progression of neurodegeneration over a 5-year period of follow-up (considering thinning of ganglion cell + inner plexiform retinal layers (GCL+IPL) in individuals with type 2 diabetes (T2D) and nonproliferative DR) and explored whetheritis associated with microaneurysmturnover (MAT), diseaselevel at baseline and severity progression.Universidade AveiroRepositório Científico do Instituto Politécnico do PortoTavares, DianaMadeira, Maria H.Marques, Inês P.Santos, TorcatoSantos, Ana RitaLobo, ConceiçãoCunha-Vaz, José2021-12-14T10:45:20Z2021-062021-06-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.22/19066engTavares, D., Madeira, M., Marques, I., Santos, T., Santos, A., Lobo, C., & Cunha-Vaz, J. (2021). Progression of Ganglion Cell-Inner Plexiform layer thickness in the initial stages of diabetic retinopathy in type 2 diabetic patients: a 5-year longitudinal study. Journal of Statistics on Health Decision, 3(1), 36-37. https://doi.org/10.34624/jshd.v3i1.248052184-579410.34624/jshd.v3i1.24805info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-03-13T13:12:53Zoai:recipp.ipp.pt:10400.22/19066Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T17:39:07.299500Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Progression of Ganglion Cell-Inner Plexiform layer thickness in the initial stages of diabetic retinopathy in type 2 diabetic patients: a 5-year longitudinal study
title Progression of Ganglion Cell-Inner Plexiform layer thickness in the initial stages of diabetic retinopathy in type 2 diabetic patients: a 5-year longitudinal study
spellingShingle Progression of Ganglion Cell-Inner Plexiform layer thickness in the initial stages of diabetic retinopathy in type 2 diabetic patients: a 5-year longitudinal study
Tavares, Diana
Diabetic retinopathy
Mixed models
Neurodegeneration
title_short Progression of Ganglion Cell-Inner Plexiform layer thickness in the initial stages of diabetic retinopathy in type 2 diabetic patients: a 5-year longitudinal study
title_full Progression of Ganglion Cell-Inner Plexiform layer thickness in the initial stages of diabetic retinopathy in type 2 diabetic patients: a 5-year longitudinal study
title_fullStr Progression of Ganglion Cell-Inner Plexiform layer thickness in the initial stages of diabetic retinopathy in type 2 diabetic patients: a 5-year longitudinal study
title_full_unstemmed Progression of Ganglion Cell-Inner Plexiform layer thickness in the initial stages of diabetic retinopathy in type 2 diabetic patients: a 5-year longitudinal study
title_sort Progression of Ganglion Cell-Inner Plexiform layer thickness in the initial stages of diabetic retinopathy in type 2 diabetic patients: a 5-year longitudinal study
author Tavares, Diana
author_facet Tavares, Diana
Madeira, Maria H.
Marques, Inês P.
Santos, Torcato
Santos, Ana Rita
Lobo, Conceição
Cunha-Vaz, José
author_role author
author2 Madeira, Maria H.
Marques, Inês P.
Santos, Torcato
Santos, Ana Rita
Lobo, Conceição
Cunha-Vaz, José
author2_role author
author
author
author
author
author
dc.contributor.none.fl_str_mv Repositório Científico do Instituto Politécnico do Porto
dc.contributor.author.fl_str_mv Tavares, Diana
Madeira, Maria H.
Marques, Inês P.
Santos, Torcato
Santos, Ana Rita
Lobo, Conceição
Cunha-Vaz, José
dc.subject.por.fl_str_mv Diabetic retinopathy
Mixed models
Neurodegeneration
topic Diabetic retinopathy
Mixed models
Neurodegeneration
description Diabetic Retinopathy (DR)is a frequent complication of DiabetesMellitus (DM) andthe main cause of vision loss in the working population in western countries. Diabetic Retinopathy has always been considered a microvascular disease, but it has been suggested that neurodegeneration is also associated with this complex pathology[1], although there is evidence indicating that the neurodegenerative process may progress independently[2]. To evaluate this potential association, we have examined the progression of neurodegeneration over a 5-year period of follow-up (considering thinning of ganglion cell + inner plexiform retinal layers (GCL+IPL) in individuals with type 2 diabetes (T2D) and nonproliferative DR) and explored whetheritis associated with microaneurysmturnover (MAT), diseaselevel at baseline and severity progression.
publishDate 2021
dc.date.none.fl_str_mv 2021-12-14T10:45:20Z
2021-06
2021-06-01T00:00:00Z
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dc.identifier.uri.fl_str_mv http://hdl.handle.net/10400.22/19066
url http://hdl.handle.net/10400.22/19066
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Tavares, D., Madeira, M., Marques, I., Santos, T., Santos, A., Lobo, C., & Cunha-Vaz, J. (2021). Progression of Ganglion Cell-Inner Plexiform layer thickness in the initial stages of diabetic retinopathy in type 2 diabetic patients: a 5-year longitudinal study. Journal of Statistics on Health Decision, 3(1), 36-37. https://doi.org/10.34624/jshd.v3i1.24805
2184-5794
10.34624/jshd.v3i1.24805
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dc.publisher.none.fl_str_mv Universidade Aveiro
publisher.none.fl_str_mv Universidade Aveiro
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