Surface modification of starch based biomaterials by oxygen plasma or UV-irradiation

Detalhes bibliográficos
Autor(a) principal: Pashkuleva, I.
Data de Publicação: 2010
Outros Autores: Marques, A. P., Vaz, F., Reis, R. L.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/1822/20611
Resumo: Radiation is widely used in biomaterials science for surface modification and sterilization. Herein, we describe the use of plasma and UV-irradiation to improve the biocompatibility of different starch-based blends in terms of cell adhesion and proliferation. Physical and chemical changes, introduced by the used methods, were evaluated by complementary techniques for surface analysis such as scanning electron microscopy, atomic force microscopy, contact angle analysis and X-ray photoelectron spectroscopy. The effect of the changed surface properties on the adhesion of osteoblast-like cells was studied by a direct contact assay. Generally, both treatments resulted in higher number of cells adhered to the modified surfaces. The importance of the improved biocompatibility resulting from the irradiation methods is further supported by the knowledge that both UV and plasma treatments can be used as cost-effective methods for sterilization of biomedical materials and devices.
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spelling Surface modification of starch based biomaterials by oxygen plasma or UV-irradiationScience & TechnologyRadiation is widely used in biomaterials science for surface modification and sterilization. Herein, we describe the use of plasma and UV-irradiation to improve the biocompatibility of different starch-based blends in terms of cell adhesion and proliferation. Physical and chemical changes, introduced by the used methods, were evaluated by complementary techniques for surface analysis such as scanning electron microscopy, atomic force microscopy, contact angle analysis and X-ray photoelectron spectroscopy. The effect of the changed surface properties on the adhesion of osteoblast-like cells was studied by a direct contact assay. Generally, both treatments resulted in higher number of cells adhered to the modified surfaces. The importance of the improved biocompatibility resulting from the irradiation methods is further supported by the knowledge that both UV and plasma treatments can be used as cost-effective methods for sterilization of biomedical materials and devices.I. P. thanks the FCT for providing her a postdoctoral scholarship (SFRH/BPD/8491/2002). This work was partially supported by FCT, through funds from the POCTI and/or FEDER programs, The European Union funded STREP Project HIPPOCRATES (NNM-3-CT-2003-505758) and the European NoE EXPERTISSUES (NMP3-CT-2004-500283).SpringerUniversidade do MinhoPashkuleva, I.Marques, A. P.Vaz, F.Reis, R. L.20102010-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/1822/20611eng0957-453010.1007/s10856-009-3831-019639265http://www.springerlink.com/content/1q640h135r2w0077/fulltext.pdfinfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-07-21T12:30:02Zoai:repositorium.sdum.uminho.pt:1822/20611Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T19:25:08.201215Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Surface modification of starch based biomaterials by oxygen plasma or UV-irradiation
title Surface modification of starch based biomaterials by oxygen plasma or UV-irradiation
spellingShingle Surface modification of starch based biomaterials by oxygen plasma or UV-irradiation
Pashkuleva, I.
Science & Technology
title_short Surface modification of starch based biomaterials by oxygen plasma or UV-irradiation
title_full Surface modification of starch based biomaterials by oxygen plasma or UV-irradiation
title_fullStr Surface modification of starch based biomaterials by oxygen plasma or UV-irradiation
title_full_unstemmed Surface modification of starch based biomaterials by oxygen plasma or UV-irradiation
title_sort Surface modification of starch based biomaterials by oxygen plasma or UV-irradiation
author Pashkuleva, I.
author_facet Pashkuleva, I.
Marques, A. P.
Vaz, F.
Reis, R. L.
author_role author
author2 Marques, A. P.
Vaz, F.
Reis, R. L.
author2_role author
author
author
dc.contributor.none.fl_str_mv Universidade do Minho
dc.contributor.author.fl_str_mv Pashkuleva, I.
Marques, A. P.
Vaz, F.
Reis, R. L.
dc.subject.por.fl_str_mv Science & Technology
topic Science & Technology
description Radiation is widely used in biomaterials science for surface modification and sterilization. Herein, we describe the use of plasma and UV-irradiation to improve the biocompatibility of different starch-based blends in terms of cell adhesion and proliferation. Physical and chemical changes, introduced by the used methods, were evaluated by complementary techniques for surface analysis such as scanning electron microscopy, atomic force microscopy, contact angle analysis and X-ray photoelectron spectroscopy. The effect of the changed surface properties on the adhesion of osteoblast-like cells was studied by a direct contact assay. Generally, both treatments resulted in higher number of cells adhered to the modified surfaces. The importance of the improved biocompatibility resulting from the irradiation methods is further supported by the knowledge that both UV and plasma treatments can be used as cost-effective methods for sterilization of biomedical materials and devices.
publishDate 2010
dc.date.none.fl_str_mv 2010
2010-01-01T00:00:00Z
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status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/1822/20611
url http://hdl.handle.net/1822/20611
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 0957-4530
10.1007/s10856-009-3831-0
19639265
http://www.springerlink.com/content/1q640h135r2w0077/fulltext.pdf
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
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dc.publisher.none.fl_str_mv Springer
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