A coupled non-Fickian model of a cardiovascular drug delivery system

Detalhes bibliográficos
Autor(a) principal: Ferreira, José Augusto
Data de Publicação: 2016
Outros Autores: Naghipoor, Jahed, Oliveira, Paula de
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10316/45267
https://doi.org/10.1093/imammb/dqv023
Resumo: A coupled non-Fickian model of a cardiovascular drug delivery system using a biodegradable drug-eluting stent is proposed. The numerical results are obtained using an implicit-explicit finite-element method. The influence of vessel stiffness on the transport of drug eluted from the stent is analysed. The results presented in this paper suggest new perspectives to adapt the drug delivery profile to the needs of the patient.
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spelling A coupled non-Fickian model of a cardiovascular drug delivery systemHumansBlood VesselsCardiovascular AgentsDrug-Eluting StentsModels, TheoreticalA coupled non-Fickian model of a cardiovascular drug delivery system using a biodegradable drug-eluting stent is proposed. The numerical results are obtained using an implicit-explicit finite-element method. The influence of vessel stiffness on the transport of drug eluted from the stent is analysed. The results presented in this paper suggest new perspectives to adapt the drug delivery profile to the needs of the patient.Oxford University Press2016info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttp://hdl.handle.net/10316/45267http://hdl.handle.net/10316/45267https://doi.org/10.1093/imammb/dqv023https://doi.org/10.1093/imammb/dqv023enghttps://doi.org/10.1093/imammb/dqv023Ferreira, José AugustoNaghipoor, JahedOliveira, Paula deinfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2021-06-29T10:03:14Zoai:estudogeral.uc.pt:10316/45267Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T20:53:21.938971Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv A coupled non-Fickian model of a cardiovascular drug delivery system
title A coupled non-Fickian model of a cardiovascular drug delivery system
spellingShingle A coupled non-Fickian model of a cardiovascular drug delivery system
Ferreira, José Augusto
Humans
Blood Vessels
Cardiovascular Agents
Drug-Eluting Stents
Models, Theoretical
title_short A coupled non-Fickian model of a cardiovascular drug delivery system
title_full A coupled non-Fickian model of a cardiovascular drug delivery system
title_fullStr A coupled non-Fickian model of a cardiovascular drug delivery system
title_full_unstemmed A coupled non-Fickian model of a cardiovascular drug delivery system
title_sort A coupled non-Fickian model of a cardiovascular drug delivery system
author Ferreira, José Augusto
author_facet Ferreira, José Augusto
Naghipoor, Jahed
Oliveira, Paula de
author_role author
author2 Naghipoor, Jahed
Oliveira, Paula de
author2_role author
author
dc.contributor.author.fl_str_mv Ferreira, José Augusto
Naghipoor, Jahed
Oliveira, Paula de
dc.subject.por.fl_str_mv Humans
Blood Vessels
Cardiovascular Agents
Drug-Eluting Stents
Models, Theoretical
topic Humans
Blood Vessels
Cardiovascular Agents
Drug-Eluting Stents
Models, Theoretical
description A coupled non-Fickian model of a cardiovascular drug delivery system using a biodegradable drug-eluting stent is proposed. The numerical results are obtained using an implicit-explicit finite-element method. The influence of vessel stiffness on the transport of drug eluted from the stent is analysed. The results presented in this paper suggest new perspectives to adapt the drug delivery profile to the needs of the patient.
publishDate 2016
dc.date.none.fl_str_mv 2016
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10316/45267
http://hdl.handle.net/10316/45267
https://doi.org/10.1093/imammb/dqv023
https://doi.org/10.1093/imammb/dqv023
url http://hdl.handle.net/10316/45267
https://doi.org/10.1093/imammb/dqv023
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv https://doi.org/10.1093/imammb/dqv023
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Oxford University Press
publisher.none.fl_str_mv Oxford University Press
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
repository.mail.fl_str_mv
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