Lead levels in non-occupationally exposed women with preeclampsia
Autor(a) principal: | |
---|---|
Data de Publicação: | 2021 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10400.22/18715 |
Resumo: | There are many controversies regarding the relationship between lead exposure andcomplications in pregnancy. Preeclampsia (PE) is a maternal hypertensive disorder which is one of the main causes of maternal and foetal mortality. The aim of our study was to assess blood lead level (BLL) in Polish women with PE (PE group, n = 66) compared with healthy, non-pregnant women (CNP group, n = 40) and healthy pregnant women (CP group, n = 40). BLL was determined by inductively coupled plasma mass spectrometry (ICP-MS). The systolic blood pressure (SBP), diastolic blood pressure (DBP) and BLL in the CP group were significantly lower than in the PE group (p < 0.001). Logistic regression analyses of BLL showed a significant positive relationship with the presence of PE. Furthermore, both the SBP and DBP values were positively associated with BLL. This study indicates that preeclamptic women tend to present with significantly higher BLL compared to healthy pregnant women. There were no differences in the BLL between the CP and CNP groups. |
id |
RCAP_4377ac02fb83cfe9a94db10625db624a |
---|---|
oai_identifier_str |
oai:recipp.ipp.pt:10400.22/18715 |
network_acronym_str |
RCAP |
network_name_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository_id_str |
7160 |
spelling |
Lead levels in non-occupationally exposed women with preeclampsia LeadPreeclampsiaPregnancyBlood pressureThere are many controversies regarding the relationship between lead exposure andcomplications in pregnancy. Preeclampsia (PE) is a maternal hypertensive disorder which is one of the main causes of maternal and foetal mortality. The aim of our study was to assess blood lead level (BLL) in Polish women with PE (PE group, n = 66) compared with healthy, non-pregnant women (CNP group, n = 40) and healthy pregnant women (CP group, n = 40). BLL was determined by inductively coupled plasma mass spectrometry (ICP-MS). The systolic blood pressure (SBP), diastolic blood pressure (DBP) and BLL in the CP group were significantly lower than in the PE group (p < 0.001). Logistic regression analyses of BLL showed a significant positive relationship with the presence of PE. Furthermore, both the SBP and DBP values were positively associated with BLL. This study indicates that preeclamptic women tend to present with significantly higher BLL compared to healthy pregnant women. There were no differences in the BLL between the CP and CNP groups.MDPIRepositório Científico do Instituto Politécnico do PortoGajewska, KatarzynaLaskowska, MarzenaAlmeida, AgostinhoPinto, EdgarSkórzyńska-Dziduszko, KatarzynaBłażewicz, Anna2021-10-15T14:06:42Z2021-052021-05-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.22/18715engGajewska, Katarzyna et al. "Lead Levels in Non-Occupationally Exposed Women with Preeclampsia." Molecules, vol. 26, no. 10, 2021, p. 3051, https://www.mdpi.com/1420-3049/26/10/3051.1420-304910.3390/molecules26103051info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-03-13T13:11:27Zoai:recipp.ipp.pt:10400.22/18715Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T17:38:47.053167Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Lead levels in non-occupationally exposed women with preeclampsia |
title |
Lead levels in non-occupationally exposed women with preeclampsia |
spellingShingle |
Lead levels in non-occupationally exposed women with preeclampsia Gajewska, Katarzyna Lead Preeclampsia Pregnancy Blood pressure |
title_short |
Lead levels in non-occupationally exposed women with preeclampsia |
title_full |
Lead levels in non-occupationally exposed women with preeclampsia |
title_fullStr |
Lead levels in non-occupationally exposed women with preeclampsia |
title_full_unstemmed |
Lead levels in non-occupationally exposed women with preeclampsia |
title_sort |
Lead levels in non-occupationally exposed women with preeclampsia |
author |
Gajewska, Katarzyna |
author_facet |
Gajewska, Katarzyna Laskowska, Marzena Almeida, Agostinho Pinto, Edgar Skórzyńska-Dziduszko, Katarzyna Błażewicz, Anna |
author_role |
author |
author2 |
Laskowska, Marzena Almeida, Agostinho Pinto, Edgar Skórzyńska-Dziduszko, Katarzyna Błażewicz, Anna |
author2_role |
author author author author author |
dc.contributor.none.fl_str_mv |
Repositório Científico do Instituto Politécnico do Porto |
dc.contributor.author.fl_str_mv |
Gajewska, Katarzyna Laskowska, Marzena Almeida, Agostinho Pinto, Edgar Skórzyńska-Dziduszko, Katarzyna Błażewicz, Anna |
dc.subject.por.fl_str_mv |
Lead Preeclampsia Pregnancy Blood pressure |
topic |
Lead Preeclampsia Pregnancy Blood pressure |
description |
There are many controversies regarding the relationship between lead exposure andcomplications in pregnancy. Preeclampsia (PE) is a maternal hypertensive disorder which is one of the main causes of maternal and foetal mortality. The aim of our study was to assess blood lead level (BLL) in Polish women with PE (PE group, n = 66) compared with healthy, non-pregnant women (CNP group, n = 40) and healthy pregnant women (CP group, n = 40). BLL was determined by inductively coupled plasma mass spectrometry (ICP-MS). The systolic blood pressure (SBP), diastolic blood pressure (DBP) and BLL in the CP group were significantly lower than in the PE group (p < 0.001). Logistic regression analyses of BLL showed a significant positive relationship with the presence of PE. Furthermore, both the SBP and DBP values were positively associated with BLL. This study indicates that preeclamptic women tend to present with significantly higher BLL compared to healthy pregnant women. There were no differences in the BLL between the CP and CNP groups. |
publishDate |
2021 |
dc.date.none.fl_str_mv |
2021-10-15T14:06:42Z 2021-05 2021-05-01T00:00:00Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10400.22/18715 |
url |
http://hdl.handle.net/10400.22/18715 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Gajewska, Katarzyna et al. "Lead Levels in Non-Occupationally Exposed Women with Preeclampsia." Molecules, vol. 26, no. 10, 2021, p. 3051, https://www.mdpi.com/1420-3049/26/10/3051. 1420-3049 10.3390/molecules26103051 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
MDPI |
publisher.none.fl_str_mv |
MDPI |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
instname_str |
Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
instacron_str |
RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
repository.mail.fl_str_mv |
|
_version_ |
1799131475934707712 |