Delving into the Variability of Supramolecular Affinity

Detalhes bibliográficos
Autor(a) principal: Gómez-González, Borja
Data de Publicação: 2024
Outros Autores: Basílio, Nuno, Vaz, Belén, Pérez-Lorenzo, Moisés, García-Río, Luis
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10362/162430
Resumo: Funding Information: This work was funded by Ministerio de Ciencia e Innovación (PID2020‐113704RB‐I00), and Xunta de Galicia (Centro Singular de Investigación de Galicia‐Accreditation 2019‐2022 ED431G 2019/06, ED431C 2022/24, and ED431C 2021/45). Publisher Copyright: © 2023 The Authors. Angewandte Chemie International Edition published by Wiley-VCH GmbH.
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spelling Delving into the Variability of Supramolecular AffinitySelf-Ion Pairing as a Central Player in Aqueous Host-Guest ChemistryHost-GuestIon-PairingMacrocyclePillarareneSupramolecular AffinityCatalysisChemistry(all)Funding Information: This work was funded by Ministerio de Ciencia e Innovación (PID2020‐113704RB‐I00), and Xunta de Galicia (Centro Singular de Investigación de Galicia‐Accreditation 2019‐2022 ED431G 2019/06, ED431C 2022/24, and ED431C 2021/45). Publisher Copyright: © 2023 The Authors. Angewandte Chemie International Edition published by Wiley-VCH GmbH.The determination of binding constants is a key matter in evaluating the strength of host–guest interactions. However, the profound impact of self-ion pairing on this parameter is often underrated in aqueous solution, leading in some cases to a misinterpretation of the true potential of supramolecular assemblies. In the present study, we aim to shed further light on this critical factor by exploring the concentration-dependent behavior of a multicharged pillararene in water. Our observations reveal an extraordinary 1-million-fold variability in the affinity of this macrocycle toward a given anion, showcasing the highly dynamic character of electrostatic interactions. We argue that these findings bring to the forefront the inherent determinism that underlies the estimation of affinity constants, a factor profoundly shaped by both the sensitivity of the instrumental technique in use and the intricacies of the experimental design itself. In terms of applications, these results may provide the opportunity to optimize the operational concentrations of multicharged hosts in different scenarios, aiming to achieve their maximum efficiency based on the intended application. Unlocking the potential of this hidden variability may pave the way for the creation of novel molecular materials with advanced functionalities.DQ - Departamento de QuímicaLAQV@REQUIMTERUNGómez-González, BorjaBasílio, NunoVaz, BelénPérez-Lorenzo, MoisésGarcía-Río, Luis2024-01-17T22:38:58Z2024-02-122024-02-12T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article11application/pdfhttp://hdl.handle.net/10362/162430eng1433-7851PURE: 81829782https://doi.org/10.1002/anie.202317553info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-05-22T18:17:30Zoai:run.unl.pt:10362/162430Portal AgregadorONGhttps://www.rcaap.pt/oai/openairemluisa.alvim@gmail.comopendoar:71602024-05-22T18:17:30Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Delving into the Variability of Supramolecular Affinity
Self-Ion Pairing as a Central Player in Aqueous Host-Guest Chemistry
title Delving into the Variability of Supramolecular Affinity
spellingShingle Delving into the Variability of Supramolecular Affinity
Gómez-González, Borja
Host-Guest
Ion-Pairing
Macrocycle
Pillararene
Supramolecular Affinity
Catalysis
Chemistry(all)
title_short Delving into the Variability of Supramolecular Affinity
title_full Delving into the Variability of Supramolecular Affinity
title_fullStr Delving into the Variability of Supramolecular Affinity
title_full_unstemmed Delving into the Variability of Supramolecular Affinity
title_sort Delving into the Variability of Supramolecular Affinity
author Gómez-González, Borja
author_facet Gómez-González, Borja
Basílio, Nuno
Vaz, Belén
Pérez-Lorenzo, Moisés
García-Río, Luis
author_role author
author2 Basílio, Nuno
Vaz, Belén
Pérez-Lorenzo, Moisés
García-Río, Luis
author2_role author
author
author
author
dc.contributor.none.fl_str_mv DQ - Departamento de Química
LAQV@REQUIMTE
RUN
dc.contributor.author.fl_str_mv Gómez-González, Borja
Basílio, Nuno
Vaz, Belén
Pérez-Lorenzo, Moisés
García-Río, Luis
dc.subject.por.fl_str_mv Host-Guest
Ion-Pairing
Macrocycle
Pillararene
Supramolecular Affinity
Catalysis
Chemistry(all)
topic Host-Guest
Ion-Pairing
Macrocycle
Pillararene
Supramolecular Affinity
Catalysis
Chemistry(all)
description Funding Information: This work was funded by Ministerio de Ciencia e Innovación (PID2020‐113704RB‐I00), and Xunta de Galicia (Centro Singular de Investigación de Galicia‐Accreditation 2019‐2022 ED431G 2019/06, ED431C 2022/24, and ED431C 2021/45). Publisher Copyright: © 2023 The Authors. Angewandte Chemie International Edition published by Wiley-VCH GmbH.
publishDate 2024
dc.date.none.fl_str_mv 2024-01-17T22:38:58Z
2024-02-12
2024-02-12T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10362/162430
url http://hdl.handle.net/10362/162430
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 1433-7851
PURE: 81829782
https://doi.org/10.1002/anie.202317553
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 11
application/pdf
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
repository.mail.fl_str_mv mluisa.alvim@gmail.com
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