Longitudinal quantitative assessment of coronary atherosclerosis related to normal systolic blood pressure maintenance in the absence of established cardiovascular disease
| Autor(a) principal: | |
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| Data de Publicação: | 2022 |
| Outros Autores: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
| Texto Completo: | http://hdl.handle.net/10362/141365 |
Resumo: | Funding Information: The project was conducted within the framework of a "Multidisciplinary Survey and Monitoring of the Gareja Rock Cut Complex, the Monument of National Value" funded by the National Agency for Cultural Heritage Preservation of Georgia and managed by the Ilia State University, Georgia, together with the Italian Institute for Environmental Protection and Research, Italy, and the support of the University of Milano-Bicocca, Italy. Data used in this work was jointly acquired and, accordingly, belongs to all three institutions. |
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Longitudinal quantitative assessment of coronary atherosclerosis related to normal systolic blood pressure maintenance in the absence of established cardiovascular diseaseatherosclerosiscoronary artery diseasecoronary computed tomography angiographysystolic blood pressureCardiology and Cardiovascular MedicineSDG 3 - Good Health and Well-beingFunding Information: The project was conducted within the framework of a "Multidisciplinary Survey and Monitoring of the Gareja Rock Cut Complex, the Monument of National Value" funded by the National Agency for Cultural Heritage Preservation of Georgia and managed by the Ilia State University, Georgia, together with the Italian Institute for Environmental Protection and Research, Italy, and the support of the University of Milano-Bicocca, Italy. Data used in this work was jointly acquired and, accordingly, belongs to all three institutions.Background: Atherosclerosis-related adverse events are commonly observed even in conditions with low cardiovascular (CV) risk. Longitudinal data regarding the association of normal systolic blood pressure maintenance (SBPmaintain) with coronary plaque volume changes (PVC) has been limited in adults without traditional CV disease. Hypothesis: Normal SBPmaintain is important to attenuate coronary atherosclerosis progression in adults without baseline CV disease. Methods: We analyzed 95 adults (56.7 ± 8.5 years; 40.0% men) without baseline CV disease who underwent serial coronary computed tomographic angiography with mean 3.5 years of follow-up. All participants were divided into two groups of normal SBPmaintain (follow-up SBP < 120 mm Hg) and ≥elevated SBPmaintain (follow-up SBP ≥ 120 mm Hg). Annualized PVC was defined as PVC divided by the interscan period. Results: Compared to participants with normal SBPmaintain, those with ≥elevated SBPmaintain had higher annualized total PVC (mm3/year) (0.0 [0.0–2.2] vs. 4.1 [0.0–13.0]; p <.001). Baseline total plaque volume (β =.10) and the levels of SBPmaintain (β =.23) and follow-up high-density lipoprotein cholesterol (β = −0.28) were associated with annualized total PVC (all p <.05). The optimal cutoff of SBPmaintain for predicting plaque progression was 118.5 mm Hg (sensitivity: 78.2%, specificity: 62.5%; area under curve: 0.700; 95% confidence interval [CI]: 0.59–0.81; p <.05). SBPmaintain ≥ 118.5 mm Hg (odds ratio [OR]: 4.03; 95% CI: 1.51–10.75) and baseline total plaque volume (OR: 1.03; 95% CI: 1.01–1.06) independently influenced coronary plaque progression (all p <.05). Conclusion: Normal SBPmaintain is substantial to attenuate coronary atherosclerosis progression in conditions without established CV disease.NOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM)RUNWon, Ki BumPark, Hyung BokHeo, RanLee, Byoung KwonLin, Fay Y.Hadamitzky, MartinKim, Yong JinSung, Ji MinConte, EdoardoAndreini, DanielePontone, GianlucaBudoff, Matthew J.Gottlieb, IlanChun, Eun JuCademartiri, FilippoMaffei, EricaPinto Marques, HugoGonçalves, Pedro de AraújoLeipsic, Jonathon A.Lee, Sang EunShin, SanghoonChoi, Jung HyunVirmani, RenuSamady, HabibChinnaiyan, KavithaBerman, Daniel S.Narula, JagatBax, Jeroen J.Min, James K.Chang, Hyuk Jae2022-07-04T22:23:59Z2022-082022-08-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10362/141365eng0160-9289PURE: 44790995https://doi.org/10.1002/clc.23870info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-10-21T01:36:25Zoai:run.unl.pt:10362/141365Portal AgregadorONGhttps://www.rcaap.pt/oai/openairemluisa.alvim@gmail.comopendoar:71602024-10-21T01:36:25Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
| dc.title.none.fl_str_mv |
Longitudinal quantitative assessment of coronary atherosclerosis related to normal systolic blood pressure maintenance in the absence of established cardiovascular disease |
| title |
Longitudinal quantitative assessment of coronary atherosclerosis related to normal systolic blood pressure maintenance in the absence of established cardiovascular disease |
| spellingShingle |
Longitudinal quantitative assessment of coronary atherosclerosis related to normal systolic blood pressure maintenance in the absence of established cardiovascular disease Won, Ki Bum atherosclerosis coronary artery disease coronary computed tomography angiography systolic blood pressure Cardiology and Cardiovascular Medicine SDG 3 - Good Health and Well-being |
| title_short |
Longitudinal quantitative assessment of coronary atherosclerosis related to normal systolic blood pressure maintenance in the absence of established cardiovascular disease |
| title_full |
Longitudinal quantitative assessment of coronary atherosclerosis related to normal systolic blood pressure maintenance in the absence of established cardiovascular disease |
| title_fullStr |
Longitudinal quantitative assessment of coronary atherosclerosis related to normal systolic blood pressure maintenance in the absence of established cardiovascular disease |
| title_full_unstemmed |
Longitudinal quantitative assessment of coronary atherosclerosis related to normal systolic blood pressure maintenance in the absence of established cardiovascular disease |
| title_sort |
Longitudinal quantitative assessment of coronary atherosclerosis related to normal systolic blood pressure maintenance in the absence of established cardiovascular disease |
| author |
Won, Ki Bum |
| author_facet |
Won, Ki Bum Park, Hyung Bok Heo, Ran Lee, Byoung Kwon Lin, Fay Y. Hadamitzky, Martin Kim, Yong Jin Sung, Ji Min Conte, Edoardo Andreini, Daniele Pontone, Gianluca Budoff, Matthew J. Gottlieb, Ilan Chun, Eun Ju Cademartiri, Filippo Maffei, Erica Pinto Marques, Hugo Gonçalves, Pedro de Araújo Leipsic, Jonathon A. Lee, Sang Eun Shin, Sanghoon Choi, Jung Hyun Virmani, Renu Samady, Habib Chinnaiyan, Kavitha Berman, Daniel S. Narula, Jagat Bax, Jeroen J. Min, James K. Chang, Hyuk Jae |
| author_role |
author |
| author2 |
Park, Hyung Bok Heo, Ran Lee, Byoung Kwon Lin, Fay Y. Hadamitzky, Martin Kim, Yong Jin Sung, Ji Min Conte, Edoardo Andreini, Daniele Pontone, Gianluca Budoff, Matthew J. Gottlieb, Ilan Chun, Eun Ju Cademartiri, Filippo Maffei, Erica Pinto Marques, Hugo Gonçalves, Pedro de Araújo Leipsic, Jonathon A. Lee, Sang Eun Shin, Sanghoon Choi, Jung Hyun Virmani, Renu Samady, Habib Chinnaiyan, Kavitha Berman, Daniel S. Narula, Jagat Bax, Jeroen J. Min, James K. Chang, Hyuk Jae |
| author2_role |
author author author author author author author author author author author author author author author author author author author author author author author author author author author author author |
| dc.contributor.none.fl_str_mv |
NOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM) RUN |
| dc.contributor.author.fl_str_mv |
Won, Ki Bum Park, Hyung Bok Heo, Ran Lee, Byoung Kwon Lin, Fay Y. Hadamitzky, Martin Kim, Yong Jin Sung, Ji Min Conte, Edoardo Andreini, Daniele Pontone, Gianluca Budoff, Matthew J. Gottlieb, Ilan Chun, Eun Ju Cademartiri, Filippo Maffei, Erica Pinto Marques, Hugo Gonçalves, Pedro de Araújo Leipsic, Jonathon A. Lee, Sang Eun Shin, Sanghoon Choi, Jung Hyun Virmani, Renu Samady, Habib Chinnaiyan, Kavitha Berman, Daniel S. Narula, Jagat Bax, Jeroen J. Min, James K. Chang, Hyuk Jae |
| dc.subject.por.fl_str_mv |
atherosclerosis coronary artery disease coronary computed tomography angiography systolic blood pressure Cardiology and Cardiovascular Medicine SDG 3 - Good Health and Well-being |
| topic |
atherosclerosis coronary artery disease coronary computed tomography angiography systolic blood pressure Cardiology and Cardiovascular Medicine SDG 3 - Good Health and Well-being |
| description |
Funding Information: The project was conducted within the framework of a "Multidisciplinary Survey and Monitoring of the Gareja Rock Cut Complex, the Monument of National Value" funded by the National Agency for Cultural Heritage Preservation of Georgia and managed by the Ilia State University, Georgia, together with the Italian Institute for Environmental Protection and Research, Italy, and the support of the University of Milano-Bicocca, Italy. Data used in this work was jointly acquired and, accordingly, belongs to all three institutions. |
| publishDate |
2022 |
| dc.date.none.fl_str_mv |
2022-07-04T22:23:59Z 2022-08 2022-08-01T00:00:00Z |
| dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
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info:eu-repo/semantics/article |
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article |
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publishedVersion |
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http://hdl.handle.net/10362/141365 |
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http://hdl.handle.net/10362/141365 |
| dc.language.iso.fl_str_mv |
eng |
| language |
eng |
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0160-9289 PURE: 44790995 https://doi.org/10.1002/clc.23870 |
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info:eu-repo/semantics/openAccess |
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openAccess |
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application/pdf |
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reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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RCAAP |
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RCAAP |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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mluisa.alvim@gmail.com |
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1817545873563844608 |