Pure autonomic failure.

Bibliographic Details
Main Author: Ducla-Soares, J L
Publication Date: 1993
Other Authors: Guerreiro, A S, Póvoa, P, Alvares, E, Guerreiro, L, Carrilho, F, Santos, M, Figueirinhas, J, Carvalho, M
Format: Article
Language: por
Source: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Download full: https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/3154
Summary: We present the case of a 64-year-old woman who, in the past 5 years, complained of constipation/diarrhea, hyposudoresis, xerostomia and xerophthalmia, dysuria and orthostatic hypotension. Cardiovascular reflexes analysis revealed sympathetic and parasympathetic failure. Norepinephrine was markedly reduced, both lying and after tilt. Norepinephrine infusion determined a significant rise in blood pressure, allowing the diagnosis of denervation hypersensitivity. The diagnosis of pure autonomic failure was made. Therapy with 9 alpha fludrocortisone and metoclopramide was initiated with marked and sustained symptomatic effect.
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spelling Pure autonomic failure.Falência autonómica pura.We present the case of a 64-year-old woman who, in the past 5 years, complained of constipation/diarrhea, hyposudoresis, xerostomia and xerophthalmia, dysuria and orthostatic hypotension. Cardiovascular reflexes analysis revealed sympathetic and parasympathetic failure. Norepinephrine was markedly reduced, both lying and after tilt. Norepinephrine infusion determined a significant rise in blood pressure, allowing the diagnosis of denervation hypersensitivity. The diagnosis of pure autonomic failure was made. Therapy with 9 alpha fludrocortisone and metoclopramide was initiated with marked and sustained symptomatic effect.We present the case of a 64-year-old woman who, in the past 5 years, complained of constipation/diarrhea, hyposudoresis, xerostomia and xerophthalmia, dysuria and orthostatic hypotension. Cardiovascular reflexes analysis revealed sympathetic and parasympathetic failure. Norepinephrine was markedly reduced, both lying and after tilt. Norepinephrine infusion determined a significant rise in blood pressure, allowing the diagnosis of denervation hypersensitivity. The diagnosis of pure autonomic failure was made. Therapy with 9 alpha fludrocortisone and metoclopramide was initiated with marked and sustained symptomatic effect.Ordem dos Médicos1993-11-30info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttps://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/3154oai:ojs.www.actamedicaportuguesa.com:article/3154Acta Médica Portuguesa; Vol. 6 No. 11 (1993): Novembro; 533-7Acta Médica Portuguesa; Vol. 6 N.º 11 (1993): Novembro; 533-71646-07580870-399Xreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAPporhttps://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/3154https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/3154/2493Ducla-Soares, J LGuerreiro, A SPóvoa, PAlvares, EGuerreiro, LCarrilho, FSantos, MFigueirinhas, JCarvalho, Minfo:eu-repo/semantics/openAccess2022-12-20T11:01:43Zoai:ojs.www.actamedicaportuguesa.com:article/3154Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T16:18:11.142610Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Pure autonomic failure.
Falência autonómica pura.
title Pure autonomic failure.
spellingShingle Pure autonomic failure.
Ducla-Soares, J L
title_short Pure autonomic failure.
title_full Pure autonomic failure.
title_fullStr Pure autonomic failure.
title_full_unstemmed Pure autonomic failure.
title_sort Pure autonomic failure.
author Ducla-Soares, J L
author_facet Ducla-Soares, J L
Guerreiro, A S
Póvoa, P
Alvares, E
Guerreiro, L
Carrilho, F
Santos, M
Figueirinhas, J
Carvalho, M
author_role author
author2 Guerreiro, A S
Póvoa, P
Alvares, E
Guerreiro, L
Carrilho, F
Santos, M
Figueirinhas, J
Carvalho, M
author2_role author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Ducla-Soares, J L
Guerreiro, A S
Póvoa, P
Alvares, E
Guerreiro, L
Carrilho, F
Santos, M
Figueirinhas, J
Carvalho, M
description We present the case of a 64-year-old woman who, in the past 5 years, complained of constipation/diarrhea, hyposudoresis, xerostomia and xerophthalmia, dysuria and orthostatic hypotension. Cardiovascular reflexes analysis revealed sympathetic and parasympathetic failure. Norepinephrine was markedly reduced, both lying and after tilt. Norepinephrine infusion determined a significant rise in blood pressure, allowing the diagnosis of denervation hypersensitivity. The diagnosis of pure autonomic failure was made. Therapy with 9 alpha fludrocortisone and metoclopramide was initiated with marked and sustained symptomatic effect.
publishDate 1993
dc.date.none.fl_str_mv 1993-11-30
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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dc.identifier.uri.fl_str_mv https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/3154
oai:ojs.www.actamedicaportuguesa.com:article/3154
url https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/3154
identifier_str_mv oai:ojs.www.actamedicaportuguesa.com:article/3154
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/3154
https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/3154/2493
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Ordem dos Médicos
publisher.none.fl_str_mv Ordem dos Médicos
dc.source.none.fl_str_mv Acta Médica Portuguesa; Vol. 6 No. 11 (1993): Novembro; 533-7
Acta Médica Portuguesa; Vol. 6 N.º 11 (1993): Novembro; 533-7
1646-0758
0870-399X
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
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collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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