New nanotechnologies for the treatment and repair of skin burns infections
Autor(a) principal: | |
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Data de Publicação: | 2020 |
Outros Autores: | , , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/1822/63829 |
Resumo: | Burn wounds are highly debilitating injuries, with significant morbidity and mortality rates worldwide. In association with the damage of the skin integrity, the risk of infection is increased, posing an obstacle to healing and potentially leading to sepsis. Another limitation against healing is associated with antibiotic resistance mainly due to the use of systemic antibiotics for the treatment of localized infections. Nanotechnology has been successful in finding strategies to incorporate antibiotics in nanoparticles for the treatment of local wounds, thereby avoiding the systemic exposure to the drug. This review focuses on the most recent advances on the use of nanoparticles in wound dressing formulations and in tissue engineering for the treatment of burn wound infections. |
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New nanotechnologies for the treatment and repair of skin burns infectionsburn wound infectionantibioticswound healingnanoparticlesScience & TechnologyBurn wounds are highly debilitating injuries, with significant morbidity and mortality rates worldwide. In association with the damage of the skin integrity, the risk of infection is increased, posing an obstacle to healing and potentially leading to sepsis. Another limitation against healing is associated with antibiotic resistance mainly due to the use of systemic antibiotics for the treatment of localized infections. Nanotechnology has been successful in finding strategies to incorporate antibiotics in nanoparticles for the treatment of local wounds, thereby avoiding the systemic exposure to the drug. This review focuses on the most recent advances on the use of nanoparticles in wound dressing formulations and in tissue engineering for the treatment of burn wound infections.The authors would like to thank the financial support received from Portuguese Science and Technology Foundation (FCT/MCT) and from European Funds (PRODER/COMPETE) under the project references M-ERA-NET/0004/2015-PAIRED and UIDB/04469/2020, co-financed by FEDER, under the Partnership Agreement PT2020.info:eu-repo/semantics/publishedVersionMDPI PublishingUniversidade do MinhoSouto, Eliana B.Ribeiro, André F.Ferreira, Maria I.Teixeira, Maria C.Shimojo, Andrea A. M.Soriano, José L.Naveros, Beatriz C.Durazzo, AlessandraLucarini, MassimoSouto, Selma B.Santini, Antonello20202020-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/1822/63829engSouto, Eliana; Ribeiro, André F.; Ferreira, Maria I.; Teixeira, Maria C.; Shimojo, Andrea A. M.; Soriano, José L.; Naveros, Beatriz C.; Durazzo, Alessandra; Lucarini, Massimo; Souto, Selma B.; Santini, Antonello, New nanotechnologies for the treatment and repair of skin burns infections. International Journal of Molecular Sciences, 21(2), 393, 20201424-67831422-00671661-659610.3390/ijms2102039331936277http://www.mdpi.com/journal/ijmsinfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-07-21T12:29:35Zoai:repositorium.sdum.uminho.pt:1822/63829Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T19:24:35.769003Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
New nanotechnologies for the treatment and repair of skin burns infections |
title |
New nanotechnologies for the treatment and repair of skin burns infections |
spellingShingle |
New nanotechnologies for the treatment and repair of skin burns infections Souto, Eliana B. burn wound infection antibiotics wound healing nanoparticles Science & Technology |
title_short |
New nanotechnologies for the treatment and repair of skin burns infections |
title_full |
New nanotechnologies for the treatment and repair of skin burns infections |
title_fullStr |
New nanotechnologies for the treatment and repair of skin burns infections |
title_full_unstemmed |
New nanotechnologies for the treatment and repair of skin burns infections |
title_sort |
New nanotechnologies for the treatment and repair of skin burns infections |
author |
Souto, Eliana B. |
author_facet |
Souto, Eliana B. Ribeiro, André F. Ferreira, Maria I. Teixeira, Maria C. Shimojo, Andrea A. M. Soriano, José L. Naveros, Beatriz C. Durazzo, Alessandra Lucarini, Massimo Souto, Selma B. Santini, Antonello |
author_role |
author |
author2 |
Ribeiro, André F. Ferreira, Maria I. Teixeira, Maria C. Shimojo, Andrea A. M. Soriano, José L. Naveros, Beatriz C. Durazzo, Alessandra Lucarini, Massimo Souto, Selma B. Santini, Antonello |
author2_role |
author author author author author author author author author author |
dc.contributor.none.fl_str_mv |
Universidade do Minho |
dc.contributor.author.fl_str_mv |
Souto, Eliana B. Ribeiro, André F. Ferreira, Maria I. Teixeira, Maria C. Shimojo, Andrea A. M. Soriano, José L. Naveros, Beatriz C. Durazzo, Alessandra Lucarini, Massimo Souto, Selma B. Santini, Antonello |
dc.subject.por.fl_str_mv |
burn wound infection antibiotics wound healing nanoparticles Science & Technology |
topic |
burn wound infection antibiotics wound healing nanoparticles Science & Technology |
description |
Burn wounds are highly debilitating injuries, with significant morbidity and mortality rates worldwide. In association with the damage of the skin integrity, the risk of infection is increased, posing an obstacle to healing and potentially leading to sepsis. Another limitation against healing is associated with antibiotic resistance mainly due to the use of systemic antibiotics for the treatment of localized infections. Nanotechnology has been successful in finding strategies to incorporate antibiotics in nanoparticles for the treatment of local wounds, thereby avoiding the systemic exposure to the drug. This review focuses on the most recent advances on the use of nanoparticles in wound dressing formulations and in tissue engineering for the treatment of burn wound infections. |
publishDate |
2020 |
dc.date.none.fl_str_mv |
2020 2020-01-01T00:00:00Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/1822/63829 |
url |
http://hdl.handle.net/1822/63829 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Souto, Eliana; Ribeiro, André F.; Ferreira, Maria I.; Teixeira, Maria C.; Shimojo, Andrea A. M.; Soriano, José L.; Naveros, Beatriz C.; Durazzo, Alessandra; Lucarini, Massimo; Souto, Selma B.; Santini, Antonello, New nanotechnologies for the treatment and repair of skin burns infections. International Journal of Molecular Sciences, 21(2), 393, 2020 1424-6783 1422-0067 1661-6596 10.3390/ijms21020393 31936277 http://www.mdpi.com/journal/ijms |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
MDPI Publishing |
publisher.none.fl_str_mv |
MDPI Publishing |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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RCAAP |
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RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
repository.mail.fl_str_mv |
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1799132726279798784 |