The world of urticaria, with and without allergy

Detalhes bibliográficos
Autor(a) principal: Chambel, Marta
Data de Publicação: 2011
Outros Autores: Antunes, João, Prates, Sara
Tipo de documento: Artigo
Idioma: por
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: https://doi.org/10.32385/rpmgf.v27i1.10824
Resumo: Urticaria is a clinical entity shared by a heterogeneous group of diseases, and must be seen as a symptom and not a disease. The characteristic cutaneous lesions are erythematous papules or with a clear central zone and a peripheral erythema, pruriginous, that disappears with digital pressure and completely regresses in less than 24 hours. In some cases it’s accompanied by angioedema, although usually it occurs isolated. Urticaria may affect up to 25% of population in some moment of life. Acute urticaria (less than 6 weeks of duration), more frequent in children, is more prevalent than the chronic form. In cases that the etiology is identified, infections, foods and medications are the most frequent causes. Insect stings and systemic diseases are more rarely involved. In chronic urticaria, allergy IgE-mediated is rare. Complementary diagnostic exams must be criterious and supported by relevant clinical data; exhaustive analytic examinations must be avoided. Most episodes of urticaria are of short duration and spontaneous resolution. Acute urticaria has an average duration of 7 days; the chronic form has a variable evolution. Regarding the treatment, elimination of the causative agent is the ideal approach, but it isn’t always possible. The first choice of symptomatic treatment are non sedative H1 antihistaminics, in higher dosage than the usually recommended. Some alternative therapeutics may be associated, but strong scientific evidence supporting their efficiency is lacking. Referral to a specialized consultation is important in some situations; some examples are allergy IgE-mediated or suspicion of systemic disease.
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spelling The world of urticaria, with and without allergyO mundo da urticária, com e sem alergiaUrticáriaAngioedemaPruridoAlergiaAntagonistas da HistaminaUrticariaAngioedemaPruritusHypersensitivityHistamine H1 AntagonistsUrticaria is a clinical entity shared by a heterogeneous group of diseases, and must be seen as a symptom and not a disease. The characteristic cutaneous lesions are erythematous papules or with a clear central zone and a peripheral erythema, pruriginous, that disappears with digital pressure and completely regresses in less than 24 hours. In some cases it’s accompanied by angioedema, although usually it occurs isolated. Urticaria may affect up to 25% of population in some moment of life. Acute urticaria (less than 6 weeks of duration), more frequent in children, is more prevalent than the chronic form. In cases that the etiology is identified, infections, foods and medications are the most frequent causes. Insect stings and systemic diseases are more rarely involved. In chronic urticaria, allergy IgE-mediated is rare. Complementary diagnostic exams must be criterious and supported by relevant clinical data; exhaustive analytic examinations must be avoided. Most episodes of urticaria are of short duration and spontaneous resolution. Acute urticaria has an average duration of 7 days; the chronic form has a variable evolution. Regarding the treatment, elimination of the causative agent is the ideal approach, but it isn’t always possible. The first choice of symptomatic treatment are non sedative H1 antihistaminics, in higher dosage than the usually recommended. Some alternative therapeutics may be associated, but strong scientific evidence supporting their efficiency is lacking. Referral to a specialized consultation is important in some situations; some examples are allergy IgE-mediated or suspicion of systemic disease.A urticária é uma entidade clínica comum a um grupo heterogéneo de doenças, devendo ser entendida como um sintoma e não como uma doença. As lesões cutâneas características são pápulas eritematosas ou com zona central pálida e eritema circundante, pruriginosas, que desaparecem à digitopressão e regridem completamente em menos de 24 horas. Embora na maioria dos casos se apresente de forma isolada, pode acompanhar-se de angioedema. A urticária pode atingir até 25% da população em qualquer momento da vida. A forma aguda (duração inferior a 6 semanas), mais frequente em crianças, é mais prevalente que a forma crónica. Nos casos em que a etiologia é identificada, as infecções, os alimentos e os fármacos são as causas mais frequentes. As picadas de insectos e as doenças sistémicas mais raramente estão implicadas. Na urticária crónica é muito raro o envolvimento de fenómenos de alergia IgE mediada. O recurso a exames auxiliares de diagnóstico deve ser criterioso e sustentado por dados clínicos relevantes, não sendo recomendável a requisição de avaliações analíticas exaustivas. Na sua maioria, os episódios de urticária são de curta duração e resolução espontânea. A urticária aguda tem uma duração média de 7 dias; já a forma crónica tem uma evolução muito variável. No que respeita à terapêutica, a eliminação do agente causal é a abordagem ideal, embora nem sempre possível. O tratamento sintomático de eleição são os antihistamínicos H1 não sedativos, em dosagem superior à habitualmente recomendada. Terapêuticas alternativas podem associar-se a estes fármacos, embora não existam fortes evidências científicas que comprovem a sua eficácia. Em algumas situações é importante referenciar a consulta especializada (Dermatologia ou Imunoalergologia); são exemplo as situações IgE mediadas (alergia alimentar ou medicamentosa), ausência de resposta à terapêutica optimizada ou alterações sugestivas de doença sistémica.Associação Portuguesa de Medicina Geral e Familiar2011-01-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttps://doi.org/10.32385/rpmgf.v27i1.10824https://doi.org/10.32385/rpmgf.v27i1.10824Portuguese Journal of Family Medicine and General Practice; Vol. 27 No. 1 (2011): Revista Portuguesa de Clínica Geral; 84-94Revista Portuguesa de Medicina Geral e Familiar; Vol. 27 Núm. 1 (2011): Revista Portuguesa de Clínica Geral; 84-94Revista Portuguesa de Medicina Geral e Familiar; Vol. 27 N.º 1 (2011): Revista Portuguesa de Clínica Geral; 84-942182-51812182-517310.32385/rpmgf.v27i1reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAPporhttps://rpmgf.pt/ojs/index.php/rpmgf/article/view/10824https://rpmgf.pt/ojs/index.php/rpmgf/article/view/10824/10560Chambel, MartaAntunes, JoãoPrates, Sarainfo:eu-repo/semantics/openAccess2024-09-17T11:59:23Zoai:ojs.rpmgf.pt:article/10824Portal AgregadorONGhttps://www.rcaap.pt/oai/openairemluisa.alvim@gmail.comopendoar:71602024-09-17T11:59:23Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv The world of urticaria, with and without allergy
O mundo da urticária, com e sem alergia
title The world of urticaria, with and without allergy
spellingShingle The world of urticaria, with and without allergy
Chambel, Marta
Urticária
Angioedema
Prurido
Alergia
Antagonistas da Histamina
Urticaria
Angioedema
Pruritus
Hypersensitivity
Histamine H1 Antagonists
title_short The world of urticaria, with and without allergy
title_full The world of urticaria, with and without allergy
title_fullStr The world of urticaria, with and without allergy
title_full_unstemmed The world of urticaria, with and without allergy
title_sort The world of urticaria, with and without allergy
author Chambel, Marta
author_facet Chambel, Marta
Antunes, João
Prates, Sara
author_role author
author2 Antunes, João
Prates, Sara
author2_role author
author
dc.contributor.author.fl_str_mv Chambel, Marta
Antunes, João
Prates, Sara
dc.subject.por.fl_str_mv Urticária
Angioedema
Prurido
Alergia
Antagonistas da Histamina
Urticaria
Angioedema
Pruritus
Hypersensitivity
Histamine H1 Antagonists
topic Urticária
Angioedema
Prurido
Alergia
Antagonistas da Histamina
Urticaria
Angioedema
Pruritus
Hypersensitivity
Histamine H1 Antagonists
description Urticaria is a clinical entity shared by a heterogeneous group of diseases, and must be seen as a symptom and not a disease. The characteristic cutaneous lesions are erythematous papules or with a clear central zone and a peripheral erythema, pruriginous, that disappears with digital pressure and completely regresses in less than 24 hours. In some cases it’s accompanied by angioedema, although usually it occurs isolated. Urticaria may affect up to 25% of population in some moment of life. Acute urticaria (less than 6 weeks of duration), more frequent in children, is more prevalent than the chronic form. In cases that the etiology is identified, infections, foods and medications are the most frequent causes. Insect stings and systemic diseases are more rarely involved. In chronic urticaria, allergy IgE-mediated is rare. Complementary diagnostic exams must be criterious and supported by relevant clinical data; exhaustive analytic examinations must be avoided. Most episodes of urticaria are of short duration and spontaneous resolution. Acute urticaria has an average duration of 7 days; the chronic form has a variable evolution. Regarding the treatment, elimination of the causative agent is the ideal approach, but it isn’t always possible. The first choice of symptomatic treatment are non sedative H1 antihistaminics, in higher dosage than the usually recommended. Some alternative therapeutics may be associated, but strong scientific evidence supporting their efficiency is lacking. Referral to a specialized consultation is important in some situations; some examples are allergy IgE-mediated or suspicion of systemic disease.
publishDate 2011
dc.date.none.fl_str_mv 2011-01-01
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
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dc.identifier.uri.fl_str_mv https://doi.org/10.32385/rpmgf.v27i1.10824
https://doi.org/10.32385/rpmgf.v27i1.10824
url https://doi.org/10.32385/rpmgf.v27i1.10824
dc.language.iso.fl_str_mv por
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dc.relation.none.fl_str_mv https://rpmgf.pt/ojs/index.php/rpmgf/article/view/10824
https://rpmgf.pt/ojs/index.php/rpmgf/article/view/10824/10560
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
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dc.publisher.none.fl_str_mv Associação Portuguesa de Medicina Geral e Familiar
publisher.none.fl_str_mv Associação Portuguesa de Medicina Geral e Familiar
dc.source.none.fl_str_mv Portuguese Journal of Family Medicine and General Practice; Vol. 27 No. 1 (2011): Revista Portuguesa de Clínica Geral; 84-94
Revista Portuguesa de Medicina Geral e Familiar; Vol. 27 Núm. 1 (2011): Revista Portuguesa de Clínica Geral; 84-94
Revista Portuguesa de Medicina Geral e Familiar; Vol. 27 N.º 1 (2011): Revista Portuguesa de Clínica Geral; 84-94
2182-5181
2182-5173
10.32385/rpmgf.v27i1
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