Meta-research metrics matter : letter regarding article “indirect tolerability comparison of Deutetrabenazine and Tetrabenazine for Huntington disease”
Autor(a) principal: | |
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Data de Publicação: | 2017 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10451/33088 |
Resumo: | © The Author(s). 2017 Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
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Meta-research metrics matter : letter regarding article “indirect tolerability comparison of Deutetrabenazine and Tetrabenazine for Huntington disease”Huntington’s diseaseTetrabenazineDeutratrabenazineIndirect treatment comparison© The Author(s). 2017 Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.Here we discuss the report by Claassen and colleagues describing an indirect treatment comparison between tetrabenazine and deutetrabenazine for chorea in Huntington's disease using individual patient data. We note the potential for discrepancies in apparently statistically significant findings, due to the rank reversal phenomenon. We provide some cautionary observations and suggestions concerning the limitations of indirect comparisons and the low likelihood that good quality evidence will become available to guide clinical decision comparing these two agents.BioMed CentralRepositório da Universidade de LisboaRodrigues, Filipe BrogueiraDuarte, Gonçalo SilvaCosta, JoãoFerreira, Joaquim JWild, Edward J.2018-05-03T11:43:42Z20172017-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10451/33088engJournal of Clinical Movement Disorders (2017) 4:192054-707210.1186/s40734-017-0067-xinfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-11-08T16:27:57Zoai:repositorio.ul.pt:10451/33088Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T21:48:16.074637Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Meta-research metrics matter : letter regarding article “indirect tolerability comparison of Deutetrabenazine and Tetrabenazine for Huntington disease” |
title |
Meta-research metrics matter : letter regarding article “indirect tolerability comparison of Deutetrabenazine and Tetrabenazine for Huntington disease” |
spellingShingle |
Meta-research metrics matter : letter regarding article “indirect tolerability comparison of Deutetrabenazine and Tetrabenazine for Huntington disease” Rodrigues, Filipe Brogueira Huntington’s disease Tetrabenazine Deutratrabenazine Indirect treatment comparison |
title_short |
Meta-research metrics matter : letter regarding article “indirect tolerability comparison of Deutetrabenazine and Tetrabenazine for Huntington disease” |
title_full |
Meta-research metrics matter : letter regarding article “indirect tolerability comparison of Deutetrabenazine and Tetrabenazine for Huntington disease” |
title_fullStr |
Meta-research metrics matter : letter regarding article “indirect tolerability comparison of Deutetrabenazine and Tetrabenazine for Huntington disease” |
title_full_unstemmed |
Meta-research metrics matter : letter regarding article “indirect tolerability comparison of Deutetrabenazine and Tetrabenazine for Huntington disease” |
title_sort |
Meta-research metrics matter : letter regarding article “indirect tolerability comparison of Deutetrabenazine and Tetrabenazine for Huntington disease” |
author |
Rodrigues, Filipe Brogueira |
author_facet |
Rodrigues, Filipe Brogueira Duarte, Gonçalo Silva Costa, João Ferreira, Joaquim J Wild, Edward J. |
author_role |
author |
author2 |
Duarte, Gonçalo Silva Costa, João Ferreira, Joaquim J Wild, Edward J. |
author2_role |
author author author author |
dc.contributor.none.fl_str_mv |
Repositório da Universidade de Lisboa |
dc.contributor.author.fl_str_mv |
Rodrigues, Filipe Brogueira Duarte, Gonçalo Silva Costa, João Ferreira, Joaquim J Wild, Edward J. |
dc.subject.por.fl_str_mv |
Huntington’s disease Tetrabenazine Deutratrabenazine Indirect treatment comparison |
topic |
Huntington’s disease Tetrabenazine Deutratrabenazine Indirect treatment comparison |
description |
© The Author(s). 2017 Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
publishDate |
2017 |
dc.date.none.fl_str_mv |
2017 2017-01-01T00:00:00Z 2018-05-03T11:43:42Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10451/33088 |
url |
http://hdl.handle.net/10451/33088 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Journal of Clinical Movement Disorders (2017) 4:19 2054-7072 10.1186/s40734-017-0067-x |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
BioMed Central |
publisher.none.fl_str_mv |
BioMed Central |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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RCAAP |
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RCAAP |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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