An Electrochemical Sensor Based on Reduced Graphene Oxide Modified Carbon Paste Electrode for Curcumin Determination in Human Blood Serum

Detalhes bibliográficos
Autor(a) principal: Rahimnejad,Mostafa
Data de Publicação: 2020
Outros Autores: Zokhtareh,Rosan, Moghadamnia,Ali Akbar, Asghary,Maryam
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://scielo.pt/scielo.php?script=sci_arttext&pid=S0872-19042020000100003
Resumo: A sensitive, accurate electrochemical sensor based on reduced graphene oxide modified carbon paste electrode (RGO/CPE) was developed to measure curcumin levels in human blood serum. The as-prepared electrode (RGO/CPE) was verified to outperform bare carbon paste electrode (CPE), with increased oxidation and reduction peaks at +0.505 V and +0.408 V, respectively. Curcumin measurement was performed using cyclic voltammetry (CV) and differential pulse voltammetry (DPV) techniques. RGO/CPE showed a desirable linear response towards curcumin, within the concentration range of 10-6000 µM; the detection limit (S/N = 3) was 3.183 µM. Moreover, electrochemical impedance spectroscopy (EIS) and field emission scanning electron microscope (FESEM) were applied to gain further insight into the electrochemical behavior of the proposed electrode. The results revealed that the usage of RGO caused increased sensitivity of the sensor response to curcumin; therefore, RGO/CPE can be considered a promising electrochemical sensor for curcumin determination in human blood serum.
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spelling An Electrochemical Sensor Based on Reduced Graphene Oxide Modified Carbon Paste Electrode for Curcumin Determination in Human Blood Serumcurcuminreduced graphene oxidecarbon paste electrodeelectrochemical sensordifferential pulse voltammetryA sensitive, accurate electrochemical sensor based on reduced graphene oxide modified carbon paste electrode (RGO/CPE) was developed to measure curcumin levels in human blood serum. The as-prepared electrode (RGO/CPE) was verified to outperform bare carbon paste electrode (CPE), with increased oxidation and reduction peaks at +0.505 V and +0.408 V, respectively. Curcumin measurement was performed using cyclic voltammetry (CV) and differential pulse voltammetry (DPV) techniques. RGO/CPE showed a desirable linear response towards curcumin, within the concentration range of 10-6000 µM; the detection limit (S/N = 3) was 3.183 µM. Moreover, electrochemical impedance spectroscopy (EIS) and field emission scanning electron microscope (FESEM) were applied to gain further insight into the electrochemical behavior of the proposed electrode. The results revealed that the usage of RGO caused increased sensitivity of the sensor response to curcumin; therefore, RGO/CPE can be considered a promising electrochemical sensor for curcumin determination in human blood serum.Sociedade Portuguesa de Electroquímica2020-01-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articletext/htmlhttp://scielo.pt/scielo.php?script=sci_arttext&pid=S0872-19042020000100003Portugaliae Electrochimica Acta v.38 n.1 2020reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAPenghttp://scielo.pt/scielo.php?script=sci_arttext&pid=S0872-19042020000100003Rahimnejad,MostafaZokhtareh,RosanMoghadamnia,Ali AkbarAsghary,Maryaminfo:eu-repo/semantics/openAccess2024-02-06T17:07:31Zoai:scielo:S0872-19042020000100003Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T02:20:25.499395Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv An Electrochemical Sensor Based on Reduced Graphene Oxide Modified Carbon Paste Electrode for Curcumin Determination in Human Blood Serum
title An Electrochemical Sensor Based on Reduced Graphene Oxide Modified Carbon Paste Electrode for Curcumin Determination in Human Blood Serum
spellingShingle An Electrochemical Sensor Based on Reduced Graphene Oxide Modified Carbon Paste Electrode for Curcumin Determination in Human Blood Serum
Rahimnejad,Mostafa
curcumin
reduced graphene oxide
carbon paste electrode
electrochemical sensor
differential pulse voltammetry
title_short An Electrochemical Sensor Based on Reduced Graphene Oxide Modified Carbon Paste Electrode for Curcumin Determination in Human Blood Serum
title_full An Electrochemical Sensor Based on Reduced Graphene Oxide Modified Carbon Paste Electrode for Curcumin Determination in Human Blood Serum
title_fullStr An Electrochemical Sensor Based on Reduced Graphene Oxide Modified Carbon Paste Electrode for Curcumin Determination in Human Blood Serum
title_full_unstemmed An Electrochemical Sensor Based on Reduced Graphene Oxide Modified Carbon Paste Electrode for Curcumin Determination in Human Blood Serum
title_sort An Electrochemical Sensor Based on Reduced Graphene Oxide Modified Carbon Paste Electrode for Curcumin Determination in Human Blood Serum
author Rahimnejad,Mostafa
author_facet Rahimnejad,Mostafa
Zokhtareh,Rosan
Moghadamnia,Ali Akbar
Asghary,Maryam
author_role author
author2 Zokhtareh,Rosan
Moghadamnia,Ali Akbar
Asghary,Maryam
author2_role author
author
author
dc.contributor.author.fl_str_mv Rahimnejad,Mostafa
Zokhtareh,Rosan
Moghadamnia,Ali Akbar
Asghary,Maryam
dc.subject.por.fl_str_mv curcumin
reduced graphene oxide
carbon paste electrode
electrochemical sensor
differential pulse voltammetry
topic curcumin
reduced graphene oxide
carbon paste electrode
electrochemical sensor
differential pulse voltammetry
description A sensitive, accurate electrochemical sensor based on reduced graphene oxide modified carbon paste electrode (RGO/CPE) was developed to measure curcumin levels in human blood serum. The as-prepared electrode (RGO/CPE) was verified to outperform bare carbon paste electrode (CPE), with increased oxidation and reduction peaks at +0.505 V and +0.408 V, respectively. Curcumin measurement was performed using cyclic voltammetry (CV) and differential pulse voltammetry (DPV) techniques. RGO/CPE showed a desirable linear response towards curcumin, within the concentration range of 10-6000 µM; the detection limit (S/N = 3) was 3.183 µM. Moreover, electrochemical impedance spectroscopy (EIS) and field emission scanning electron microscope (FESEM) were applied to gain further insight into the electrochemical behavior of the proposed electrode. The results revealed that the usage of RGO caused increased sensitivity of the sensor response to curcumin; therefore, RGO/CPE can be considered a promising electrochemical sensor for curcumin determination in human blood serum.
publishDate 2020
dc.date.none.fl_str_mv 2020-01-01
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://scielo.pt/scielo.php?script=sci_arttext&pid=S0872-19042020000100003
url http://scielo.pt/scielo.php?script=sci_arttext&pid=S0872-19042020000100003
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv http://scielo.pt/scielo.php?script=sci_arttext&pid=S0872-19042020000100003
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Portuguesa de Electroquímica
publisher.none.fl_str_mv Sociedade Portuguesa de Electroquímica
dc.source.none.fl_str_mv Portugaliae Electrochimica Acta v.38 n.1 2020
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
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reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
repository.mail.fl_str_mv
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