Rodent models: what is their importance for cancer study?

Detalhes bibliográficos
Autor(a) principal: Faustino-Rocha, Ana Isabel
Data de Publicação: 2021
Tipo de documento: Artigo de conferência
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10174/32610
Resumo: Cancer is one of the most frequent diseases worldwide, accounting for approximately 10 million deaths in 2020. The most common cancers in 2020 were: breast, lung, colon and rectum, prostate, skin, and stomach. Cancer arises from the conversion of normal cells into initiated cells as a result of the interaction between intrinsic (genetic) and extrinsic factors, namely physical agents (ultraviolet radiation), chemical agents (asbestos, components of tobacco smoke, arsenic) and biological agents (Helicobater pylori, Schistosoma haematobium, hepatitis virus). Animal models are very useful to understand and follow several diseases, including cancer. In this way, in vivo studies are essential to improve and discover new strategies to prevent and treat cancer more effectively. This presentation intends to describe the rodent models available for cancer study, highlighting their advantages and disadvantages, as well as their potential in the evaluation of several drugs and natural compounds for cancer treatment.
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spelling Rodent models: what is their importance for cancer study?carcinogenesismicerat modelCancer is one of the most frequent diseases worldwide, accounting for approximately 10 million deaths in 2020. The most common cancers in 2020 were: breast, lung, colon and rectum, prostate, skin, and stomach. Cancer arises from the conversion of normal cells into initiated cells as a result of the interaction between intrinsic (genetic) and extrinsic factors, namely physical agents (ultraviolet radiation), chemical agents (asbestos, components of tobacco smoke, arsenic) and biological agents (Helicobater pylori, Schistosoma haematobium, hepatitis virus). Animal models are very useful to understand and follow several diseases, including cancer. In this way, in vivo studies are essential to improve and discover new strategies to prevent and treat cancer more effectively. This presentation intends to describe the rodent models available for cancer study, highlighting their advantages and disadvantages, as well as their potential in the evaluation of several drugs and natural compounds for cancer treatment.2022-10-19T14:09:43Z2022-10-192021-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/conferenceObjecthttp://hdl.handle.net/10174/32610http://hdl.handle.net/10174/32610engFaustino-Rocha AI. 2021. Rodent models: what is their importance for cancer study? Webinar on Animal and Veterinary Science, 13 de junho.simsimnaoanafaustino@uevora.pt206Faustino-Rocha, Ana Isabelinfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-01-03T19:27:37Zoai:dspace.uevora.pt:10174/32610Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T01:19:34.319951Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Rodent models: what is their importance for cancer study?
title Rodent models: what is their importance for cancer study?
spellingShingle Rodent models: what is their importance for cancer study?
Faustino-Rocha, Ana Isabel
carcinogenesis
mice
rat model
title_short Rodent models: what is their importance for cancer study?
title_full Rodent models: what is their importance for cancer study?
title_fullStr Rodent models: what is their importance for cancer study?
title_full_unstemmed Rodent models: what is their importance for cancer study?
title_sort Rodent models: what is their importance for cancer study?
author Faustino-Rocha, Ana Isabel
author_facet Faustino-Rocha, Ana Isabel
author_role author
dc.contributor.author.fl_str_mv Faustino-Rocha, Ana Isabel
dc.subject.por.fl_str_mv carcinogenesis
mice
rat model
topic carcinogenesis
mice
rat model
description Cancer is one of the most frequent diseases worldwide, accounting for approximately 10 million deaths in 2020. The most common cancers in 2020 were: breast, lung, colon and rectum, prostate, skin, and stomach. Cancer arises from the conversion of normal cells into initiated cells as a result of the interaction between intrinsic (genetic) and extrinsic factors, namely physical agents (ultraviolet radiation), chemical agents (asbestos, components of tobacco smoke, arsenic) and biological agents (Helicobater pylori, Schistosoma haematobium, hepatitis virus). Animal models are very useful to understand and follow several diseases, including cancer. In this way, in vivo studies are essential to improve and discover new strategies to prevent and treat cancer more effectively. This presentation intends to describe the rodent models available for cancer study, highlighting their advantages and disadvantages, as well as their potential in the evaluation of several drugs and natural compounds for cancer treatment.
publishDate 2021
dc.date.none.fl_str_mv 2021-01-01T00:00:00Z
2022-10-19T14:09:43Z
2022-10-19
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dc.identifier.uri.fl_str_mv http://hdl.handle.net/10174/32610
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dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Faustino-Rocha AI. 2021. Rodent models: what is their importance for cancer study? Webinar on Animal and Veterinary Science, 13 de junho.
sim
sim
nao
anafaustino@uevora.pt
206
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