Rodent models: what is their importance for cancer study?
Autor(a) principal: | |
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Data de Publicação: | 2021 |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10174/30999 |
Resumo: | Abstract: Cancer is one of the most frequent diseases worldwide, accounting for approximately 10 million deaths in 2020. The most common cancers in 2020 were: breast, lung, colon and rectum, prostate, skin, and stomach. Cancer arises from the conversion of normal cells into initiated cells as a result of the interaction between intrinsic (genetic) and extrinsic factors, namely physical agents (ultraviolet radiation), chemical agents (asbestos, components of tobacco smoke, arsenic) and biological agents (Helicobater pylori, Schistosoma haematobium, hepatitis virus). Animal models are very useful to understand and follow several diseases, including cancer. In this way, in vivo studies are essential to improve and discover new strategies to prevent and treat cancer more effectively. This presentation intends to describe the rodent models available for cancer study, highlighting their advantages and disadvantages, as well as their potential in the evaluation of several drugs and natural compounds for cancer treatment. |
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Rodent models: what is their importance for cancer study?Abstract: Cancer is one of the most frequent diseases worldwide, accounting for approximately 10 million deaths in 2020. The most common cancers in 2020 were: breast, lung, colon and rectum, prostate, skin, and stomach. Cancer arises from the conversion of normal cells into initiated cells as a result of the interaction between intrinsic (genetic) and extrinsic factors, namely physical agents (ultraviolet radiation), chemical agents (asbestos, components of tobacco smoke, arsenic) and biological agents (Helicobater pylori, Schistosoma haematobium, hepatitis virus). Animal models are very useful to understand and follow several diseases, including cancer. In this way, in vivo studies are essential to improve and discover new strategies to prevent and treat cancer more effectively. This presentation intends to describe the rodent models available for cancer study, highlighting their advantages and disadvantages, as well as their potential in the evaluation of several drugs and natural compounds for cancer treatment.Webinar on Animal and Veterinary Science2022-01-31T16:05:39Z2022-01-312021-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttp://hdl.handle.net/10174/30999http://hdl.handle.net/10174/30999engFaustino-Rocha AI. 2021. Rodent models: what is their importance for cancer study? Webinar on Animal and Veterinary Science, p. 12, 13 de junho.12anafaustino@uevora.pt206Faustino-Rocha, Ana Isabelinfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-01-03T19:27:40Zoai:dspace.uevora.pt:10174/30999Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T01:19:35.267326Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Rodent models: what is their importance for cancer study? |
title |
Rodent models: what is their importance for cancer study? |
spellingShingle |
Rodent models: what is their importance for cancer study? Faustino-Rocha, Ana Isabel |
title_short |
Rodent models: what is their importance for cancer study? |
title_full |
Rodent models: what is their importance for cancer study? |
title_fullStr |
Rodent models: what is their importance for cancer study? |
title_full_unstemmed |
Rodent models: what is their importance for cancer study? |
title_sort |
Rodent models: what is their importance for cancer study? |
author |
Faustino-Rocha, Ana Isabel |
author_facet |
Faustino-Rocha, Ana Isabel |
author_role |
author |
dc.contributor.author.fl_str_mv |
Faustino-Rocha, Ana Isabel |
description |
Abstract: Cancer is one of the most frequent diseases worldwide, accounting for approximately 10 million deaths in 2020. The most common cancers in 2020 were: breast, lung, colon and rectum, prostate, skin, and stomach. Cancer arises from the conversion of normal cells into initiated cells as a result of the interaction between intrinsic (genetic) and extrinsic factors, namely physical agents (ultraviolet radiation), chemical agents (asbestos, components of tobacco smoke, arsenic) and biological agents (Helicobater pylori, Schistosoma haematobium, hepatitis virus). Animal models are very useful to understand and follow several diseases, including cancer. In this way, in vivo studies are essential to improve and discover new strategies to prevent and treat cancer more effectively. This presentation intends to describe the rodent models available for cancer study, highlighting their advantages and disadvantages, as well as their potential in the evaluation of several drugs and natural compounds for cancer treatment. |
publishDate |
2021 |
dc.date.none.fl_str_mv |
2021-01-01T00:00:00Z 2022-01-31T16:05:39Z 2022-01-31 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10174/30999 http://hdl.handle.net/10174/30999 |
url |
http://hdl.handle.net/10174/30999 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Faustino-Rocha AI. 2021. Rodent models: what is their importance for cancer study? Webinar on Animal and Veterinary Science, p. 12, 13 de junho. 12 anafaustino@uevora.pt 206 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.publisher.none.fl_str_mv |
Webinar on Animal and Veterinary Science |
publisher.none.fl_str_mv |
Webinar on Animal and Veterinary Science |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
instacron_str |
RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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1799136677127520256 |