Preliminary evaluation of zeolite-based platforms as potential dual drug delivery systems against microbial infections in the tumor microenvironment

Detalhes bibliográficos
Autor(a) principal: Bertão, Ana Raquel
Data de Publicação: 2024
Outros Autores: Ivasiv, Viktoriya, Almeida Aguiar, Cristina, Correia, Patrícia R., Fonseca, António M., Bañobre-López, Manuel, Baltazar, Fátima, Neves, Isabel C.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: https://hdl.handle.net/1822/87176
Resumo: Several zeolite-based delivery systems (ZDS) built with faujasite structure were prepared containing silver (Ag+) and 5-Fluorouracil (5-FU) as antimicrobial and antineoplastic agents, respectively. The idea behind this drug combination is an answer to the increasing evidence of colonization of tumor microenvironments by pathogenic microorganisms and their active role in tumor growth. Two ZDS with a fixed load of 5-FU and different silver loads, Ag7(5-FU).
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spelling Preliminary evaluation of zeolite-based platforms as potential dual drug delivery systems against microbial infections in the tumor microenvironmentZeolite5-FluorouracilSilverMicrobial infectionsTumor microenvironmentSeveral zeolite-based delivery systems (ZDS) built with faujasite structure were prepared containing silver (Ag+) and 5-Fluorouracil (5-FU) as antimicrobial and antineoplastic agents, respectively. The idea behind this drug combination is an answer to the increasing evidence of colonization of tumor microenvironments by pathogenic microorganisms and their active role in tumor growth. Two ZDS with a fixed load of 5-FU and different silver loads, Ag7(5-FU).FCT -Fundação para a Ciência e a Tecnologia(UID/QUI/0686/2020)info:eu-repo/semantics/publishedVersionElsevierUniversidade do MinhoBertão, Ana RaquelIvasiv, ViktoriyaAlmeida Aguiar, CristinaCorreia, Patrícia R.Fonseca, António M.Bañobre-López, ManuelBaltazar, FátimaNeves, Isabel C.2024-01-152024-01-15T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttps://hdl.handle.net/1822/87176engBertão, Ana Raquel; Ivasiv, Viktoriya; Almeida-Aguiar, Cristina; Correia, Patricia R.; Fonseca, António; Bañobre-López, Manuel; Baltazar, Fátima; Neves, Isabel C., Preliminary evaluation of zeolite-based platforms as potential dual drug delivery systems against microbial infections in the tumor microenvironment. Microporous and Mesoporous Materials, 364(112871), 20241387-181110.1016/j.micromeso.2023.112871https://www.journals.elsevier.com/microporous-and-mesoporous-materialsinfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-02-24T01:22:58Zoai:repositorium.sdum.uminho.pt:1822/87176Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T22:37:54.394890Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Preliminary evaluation of zeolite-based platforms as potential dual drug delivery systems against microbial infections in the tumor microenvironment
title Preliminary evaluation of zeolite-based platforms as potential dual drug delivery systems against microbial infections in the tumor microenvironment
spellingShingle Preliminary evaluation of zeolite-based platforms as potential dual drug delivery systems against microbial infections in the tumor microenvironment
Bertão, Ana Raquel
Zeolite
5-Fluorouracil
Silver
Microbial infections
Tumor microenvironment
title_short Preliminary evaluation of zeolite-based platforms as potential dual drug delivery systems against microbial infections in the tumor microenvironment
title_full Preliminary evaluation of zeolite-based platforms as potential dual drug delivery systems against microbial infections in the tumor microenvironment
title_fullStr Preliminary evaluation of zeolite-based platforms as potential dual drug delivery systems against microbial infections in the tumor microenvironment
title_full_unstemmed Preliminary evaluation of zeolite-based platforms as potential dual drug delivery systems against microbial infections in the tumor microenvironment
title_sort Preliminary evaluation of zeolite-based platforms as potential dual drug delivery systems against microbial infections in the tumor microenvironment
author Bertão, Ana Raquel
author_facet Bertão, Ana Raquel
Ivasiv, Viktoriya
Almeida Aguiar, Cristina
Correia, Patrícia R.
Fonseca, António M.
Bañobre-López, Manuel
Baltazar, Fátima
Neves, Isabel C.
author_role author
author2 Ivasiv, Viktoriya
Almeida Aguiar, Cristina
Correia, Patrícia R.
Fonseca, António M.
Bañobre-López, Manuel
Baltazar, Fátima
Neves, Isabel C.
author2_role author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Universidade do Minho
dc.contributor.author.fl_str_mv Bertão, Ana Raquel
Ivasiv, Viktoriya
Almeida Aguiar, Cristina
Correia, Patrícia R.
Fonseca, António M.
Bañobre-López, Manuel
Baltazar, Fátima
Neves, Isabel C.
dc.subject.por.fl_str_mv Zeolite
5-Fluorouracil
Silver
Microbial infections
Tumor microenvironment
topic Zeolite
5-Fluorouracil
Silver
Microbial infections
Tumor microenvironment
description Several zeolite-based delivery systems (ZDS) built with faujasite structure were prepared containing silver (Ag+) and 5-Fluorouracil (5-FU) as antimicrobial and antineoplastic agents, respectively. The idea behind this drug combination is an answer to the increasing evidence of colonization of tumor microenvironments by pathogenic microorganisms and their active role in tumor growth. Two ZDS with a fixed load of 5-FU and different silver loads, Ag7(5-FU).
publishDate 2024
dc.date.none.fl_str_mv 2024-01-15
2024-01-15T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://hdl.handle.net/1822/87176
url https://hdl.handle.net/1822/87176
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Bertão, Ana Raquel; Ivasiv, Viktoriya; Almeida-Aguiar, Cristina; Correia, Patricia R.; Fonseca, António; Bañobre-López, Manuel; Baltazar, Fátima; Neves, Isabel C., Preliminary evaluation of zeolite-based platforms as potential dual drug delivery systems against microbial infections in the tumor microenvironment. Microporous and Mesoporous Materials, 364(112871), 2024
1387-1811
10.1016/j.micromeso.2023.112871
https://www.journals.elsevier.com/microporous-and-mesoporous-materials
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
repository.mail.fl_str_mv
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