Prostatic Arterial Embolization to Treat Benign Prostatic Hyperplasia
Autor(a) principal: | |
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Data de Publicação: | 2011 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10400.17/1193 |
Resumo: | PURPOSE: To evaluate whether prostatic arterial embolization (PAE) might be a feasible procedure to treat lower urinary tract symptoms associated with benign prostatic hyperplasia (BPH). MATERIALS AND METHODS: Fifteen patients (age range, 62-82 years; mean age, 74.1 y) with symptomatic BPH after failure of medical treatment were selected for PAE with nonspherical 200-μm polyvinyl alcohol particles. The procedure was performed by a single femoral approach. Technical success was considered when selective prostatic arterial catheterization and embolization was achieved on at least one pelvic side. RESULTS: PAE was technically successful in 14 of the 15 patients (93.3%). There was a mean follow-up of 7.9 months (range, 3-12 months). International Prostate Symptom Score decreased a mean of 6.5 points (P = .005), quality of life improved 1.14 points (P = .065), International Index of Erectile Function increased 1.7 points (P = .063), and peak urinary flow increased 3.85 mL/sec (P = .015). There was a mean prostate-specific antigen reduction of 2.27 ng/mL (P = .072) and a mean prostate volume decrease of 26.5 mL (P = .0001) by ultrasound and 28.9 mL (P = .008) by magnetic resonance imaging. There was one major complication (a 1.5-cm(2) ischemic area of the bladder wall) and four clinical failures (28.6%). CONCLUSIONS: In this small group of patients, PAE was a feasible procedure, with preliminary results and short-term follow-up suggesting good symptom control without sexual dysfunction in suitable candidates, associated with a reduction in prostate volume. |
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Prostatic Arterial Embolization to Treat Benign Prostatic HyperplasiaArtériasBiópsiaEmbolização TerapêuticaEfeitos AdversosEstudos de ViabilidadeIsquemiaRessonância MagnéticaTamanho do ÓrgãoErecção do PénisProjectos PilotoÁlcool de PolivinilPortugalEstudos ProspectivosPróstataUltrassonografiaAntigénio Prostático EspecíficoHiperplasia ProstáticaQualidade de VidaRecuperação da Função FisiológicaFactores de TempoResultado de TratamentoBexigaUrodinâmicaPURPOSE: To evaluate whether prostatic arterial embolization (PAE) might be a feasible procedure to treat lower urinary tract symptoms associated with benign prostatic hyperplasia (BPH). MATERIALS AND METHODS: Fifteen patients (age range, 62-82 years; mean age, 74.1 y) with symptomatic BPH after failure of medical treatment were selected for PAE with nonspherical 200-μm polyvinyl alcohol particles. The procedure was performed by a single femoral approach. Technical success was considered when selective prostatic arterial catheterization and embolization was achieved on at least one pelvic side. RESULTS: PAE was technically successful in 14 of the 15 patients (93.3%). There was a mean follow-up of 7.9 months (range, 3-12 months). International Prostate Symptom Score decreased a mean of 6.5 points (P = .005), quality of life improved 1.14 points (P = .065), International Index of Erectile Function increased 1.7 points (P = .063), and peak urinary flow increased 3.85 mL/sec (P = .015). There was a mean prostate-specific antigen reduction of 2.27 ng/mL (P = .072) and a mean prostate volume decrease of 26.5 mL (P = .0001) by ultrasound and 28.9 mL (P = .008) by magnetic resonance imaging. There was one major complication (a 1.5-cm(2) ischemic area of the bladder wall) and four clinical failures (28.6%). CONCLUSIONS: In this small group of patients, PAE was a feasible procedure, with preliminary results and short-term follow-up suggesting good symptom control without sexual dysfunction in suitable candidates, associated with a reduction in prostate volume.ElsevierRepositório do Centro Hospitalar Universitário de Lisboa Central, EPEPisco, JMPinheiro, LCBilhim, TDuarte, MMendes, JOliveira, A2013-03-27T17:21:26Z20112011-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.17/1193engJ Vasc Interv Radiol. 2011 Jan;22(1):11-9; quiz 20info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-03-10T09:29:59Zoai:repositorio.chlc.min-saude.pt:10400.17/1193Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T17:18:45.185308Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Prostatic Arterial Embolization to Treat Benign Prostatic Hyperplasia |
title |
Prostatic Arterial Embolization to Treat Benign Prostatic Hyperplasia |
spellingShingle |
Prostatic Arterial Embolization to Treat Benign Prostatic Hyperplasia Pisco, JM Artérias Biópsia Embolização Terapêutica Efeitos Adversos Estudos de Viabilidade Isquemia Ressonância Magnética Tamanho do Órgão Erecção do Pénis Projectos Piloto Álcool de Polivinil Portugal Estudos Prospectivos Próstata Ultrassonografia Antigénio Prostático Específico Hiperplasia Prostática Qualidade de Vida Recuperação da Função Fisiológica Factores de Tempo Resultado de Tratamento Bexiga Urodinâmica |
title_short |
Prostatic Arterial Embolization to Treat Benign Prostatic Hyperplasia |
title_full |
Prostatic Arterial Embolization to Treat Benign Prostatic Hyperplasia |
title_fullStr |
Prostatic Arterial Embolization to Treat Benign Prostatic Hyperplasia |
title_full_unstemmed |
Prostatic Arterial Embolization to Treat Benign Prostatic Hyperplasia |
title_sort |
Prostatic Arterial Embolization to Treat Benign Prostatic Hyperplasia |
author |
Pisco, JM |
author_facet |
Pisco, JM Pinheiro, LC Bilhim, T Duarte, M Mendes, J Oliveira, A |
author_role |
author |
author2 |
Pinheiro, LC Bilhim, T Duarte, M Mendes, J Oliveira, A |
author2_role |
author author author author author |
dc.contributor.none.fl_str_mv |
Repositório do Centro Hospitalar Universitário de Lisboa Central, EPE |
dc.contributor.author.fl_str_mv |
Pisco, JM Pinheiro, LC Bilhim, T Duarte, M Mendes, J Oliveira, A |
dc.subject.por.fl_str_mv |
Artérias Biópsia Embolização Terapêutica Efeitos Adversos Estudos de Viabilidade Isquemia Ressonância Magnética Tamanho do Órgão Erecção do Pénis Projectos Piloto Álcool de Polivinil Portugal Estudos Prospectivos Próstata Ultrassonografia Antigénio Prostático Específico Hiperplasia Prostática Qualidade de Vida Recuperação da Função Fisiológica Factores de Tempo Resultado de Tratamento Bexiga Urodinâmica |
topic |
Artérias Biópsia Embolização Terapêutica Efeitos Adversos Estudos de Viabilidade Isquemia Ressonância Magnética Tamanho do Órgão Erecção do Pénis Projectos Piloto Álcool de Polivinil Portugal Estudos Prospectivos Próstata Ultrassonografia Antigénio Prostático Específico Hiperplasia Prostática Qualidade de Vida Recuperação da Função Fisiológica Factores de Tempo Resultado de Tratamento Bexiga Urodinâmica |
description |
PURPOSE: To evaluate whether prostatic arterial embolization (PAE) might be a feasible procedure to treat lower urinary tract symptoms associated with benign prostatic hyperplasia (BPH). MATERIALS AND METHODS: Fifteen patients (age range, 62-82 years; mean age, 74.1 y) with symptomatic BPH after failure of medical treatment were selected for PAE with nonspherical 200-μm polyvinyl alcohol particles. The procedure was performed by a single femoral approach. Technical success was considered when selective prostatic arterial catheterization and embolization was achieved on at least one pelvic side. RESULTS: PAE was technically successful in 14 of the 15 patients (93.3%). There was a mean follow-up of 7.9 months (range, 3-12 months). International Prostate Symptom Score decreased a mean of 6.5 points (P = .005), quality of life improved 1.14 points (P = .065), International Index of Erectile Function increased 1.7 points (P = .063), and peak urinary flow increased 3.85 mL/sec (P = .015). There was a mean prostate-specific antigen reduction of 2.27 ng/mL (P = .072) and a mean prostate volume decrease of 26.5 mL (P = .0001) by ultrasound and 28.9 mL (P = .008) by magnetic resonance imaging. There was one major complication (a 1.5-cm(2) ischemic area of the bladder wall) and four clinical failures (28.6%). CONCLUSIONS: In this small group of patients, PAE was a feasible procedure, with preliminary results and short-term follow-up suggesting good symptom control without sexual dysfunction in suitable candidates, associated with a reduction in prostate volume. |
publishDate |
2011 |
dc.date.none.fl_str_mv |
2011 2011-01-01T00:00:00Z 2013-03-27T17:21:26Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10400.17/1193 |
url |
http://hdl.handle.net/10400.17/1193 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
J Vasc Interv Radiol. 2011 Jan;22(1):11-9; quiz 20 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Elsevier |
publisher.none.fl_str_mv |
Elsevier |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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RCAAP |
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RCAAP |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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