Prostatic Arterial Embolization to Treat Benign Prostatic Hyperplasia

Detalhes bibliográficos
Autor(a) principal: Pisco, JM
Data de Publicação: 2011
Outros Autores: Pinheiro, LC, Bilhim, T, Duarte, M, Mendes, J, Oliveira, A
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10400.17/1193
Resumo: PURPOSE: To evaluate whether prostatic arterial embolization (PAE) might be a feasible procedure to treat lower urinary tract symptoms associated with benign prostatic hyperplasia (BPH). MATERIALS AND METHODS: Fifteen patients (age range, 62-82 years; mean age, 74.1 y) with symptomatic BPH after failure of medical treatment were selected for PAE with nonspherical 200-μm polyvinyl alcohol particles. The procedure was performed by a single femoral approach. Technical success was considered when selective prostatic arterial catheterization and embolization was achieved on at least one pelvic side. RESULTS: PAE was technically successful in 14 of the 15 patients (93.3%). There was a mean follow-up of 7.9 months (range, 3-12 months). International Prostate Symptom Score decreased a mean of 6.5 points (P = .005), quality of life improved 1.14 points (P = .065), International Index of Erectile Function increased 1.7 points (P = .063), and peak urinary flow increased 3.85 mL/sec (P = .015). There was a mean prostate-specific antigen reduction of 2.27 ng/mL (P = .072) and a mean prostate volume decrease of 26.5 mL (P = .0001) by ultrasound and 28.9 mL (P = .008) by magnetic resonance imaging. There was one major complication (a 1.5-cm(2) ischemic area of the bladder wall) and four clinical failures (28.6%). CONCLUSIONS: In this small group of patients, PAE was a feasible procedure, with preliminary results and short-term follow-up suggesting good symptom control without sexual dysfunction in suitable candidates, associated with a reduction in prostate volume.
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spelling Prostatic Arterial Embolization to Treat Benign Prostatic HyperplasiaArtériasBiópsiaEmbolização TerapêuticaEfeitos AdversosEstudos de ViabilidadeIsquemiaRessonância MagnéticaTamanho do ÓrgãoErecção do PénisProjectos PilotoÁlcool de PolivinilPortugalEstudos ProspectivosPróstataUltrassonografiaAntigénio Prostático EspecíficoHiperplasia ProstáticaQualidade de VidaRecuperação da Função FisiológicaFactores de TempoResultado de TratamentoBexigaUrodinâmicaPURPOSE: To evaluate whether prostatic arterial embolization (PAE) might be a feasible procedure to treat lower urinary tract symptoms associated with benign prostatic hyperplasia (BPH). MATERIALS AND METHODS: Fifteen patients (age range, 62-82 years; mean age, 74.1 y) with symptomatic BPH after failure of medical treatment were selected for PAE with nonspherical 200-μm polyvinyl alcohol particles. The procedure was performed by a single femoral approach. Technical success was considered when selective prostatic arterial catheterization and embolization was achieved on at least one pelvic side. RESULTS: PAE was technically successful in 14 of the 15 patients (93.3%). There was a mean follow-up of 7.9 months (range, 3-12 months). International Prostate Symptom Score decreased a mean of 6.5 points (P = .005), quality of life improved 1.14 points (P = .065), International Index of Erectile Function increased 1.7 points (P = .063), and peak urinary flow increased 3.85 mL/sec (P = .015). There was a mean prostate-specific antigen reduction of 2.27 ng/mL (P = .072) and a mean prostate volume decrease of 26.5 mL (P = .0001) by ultrasound and 28.9 mL (P = .008) by magnetic resonance imaging. There was one major complication (a 1.5-cm(2) ischemic area of the bladder wall) and four clinical failures (28.6%). CONCLUSIONS: In this small group of patients, PAE was a feasible procedure, with preliminary results and short-term follow-up suggesting good symptom control without sexual dysfunction in suitable candidates, associated with a reduction in prostate volume.ElsevierRepositório do Centro Hospitalar Universitário de Lisboa Central, EPEPisco, JMPinheiro, LCBilhim, TDuarte, MMendes, JOliveira, A2013-03-27T17:21:26Z20112011-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.17/1193engJ Vasc Interv Radiol. 2011 Jan;22(1):11-9; quiz 20info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-10-28T10:25:52Zoai:repositorio.chlc.pt:10400.17/1193Portal AgregadorONGhttps://www.rcaap.pt/oai/openairemluisa.alvim@gmail.comopendoar:71602024-10-28T10:25:52Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Prostatic Arterial Embolization to Treat Benign Prostatic Hyperplasia
title Prostatic Arterial Embolization to Treat Benign Prostatic Hyperplasia
spellingShingle Prostatic Arterial Embolization to Treat Benign Prostatic Hyperplasia
Pisco, JM
Artérias
Biópsia
Embolização Terapêutica
Efeitos Adversos
Estudos de Viabilidade
Isquemia
Ressonância Magnética
Tamanho do Órgão
Erecção do Pénis
Projectos Piloto
Álcool de Polivinil
Portugal
Estudos Prospectivos
Próstata
Ultrassonografia
Antigénio Prostático Específico
Hiperplasia Prostática
Qualidade de Vida
Recuperação da Função Fisiológica
Factores de Tempo
Resultado de Tratamento
Bexiga
Urodinâmica
title_short Prostatic Arterial Embolization to Treat Benign Prostatic Hyperplasia
title_full Prostatic Arterial Embolization to Treat Benign Prostatic Hyperplasia
title_fullStr Prostatic Arterial Embolization to Treat Benign Prostatic Hyperplasia
title_full_unstemmed Prostatic Arterial Embolization to Treat Benign Prostatic Hyperplasia
title_sort Prostatic Arterial Embolization to Treat Benign Prostatic Hyperplasia
author Pisco, JM
author_facet Pisco, JM
Pinheiro, LC
Bilhim, T
Duarte, M
Mendes, J
Oliveira, A
author_role author
author2 Pinheiro, LC
Bilhim, T
Duarte, M
Mendes, J
Oliveira, A
author2_role author
author
author
author
author
dc.contributor.none.fl_str_mv Repositório do Centro Hospitalar Universitário de Lisboa Central, EPE
dc.contributor.author.fl_str_mv Pisco, JM
Pinheiro, LC
Bilhim, T
Duarte, M
Mendes, J
Oliveira, A
dc.subject.por.fl_str_mv Artérias
Biópsia
Embolização Terapêutica
Efeitos Adversos
Estudos de Viabilidade
Isquemia
Ressonância Magnética
Tamanho do Órgão
Erecção do Pénis
Projectos Piloto
Álcool de Polivinil
Portugal
Estudos Prospectivos
Próstata
Ultrassonografia
Antigénio Prostático Específico
Hiperplasia Prostática
Qualidade de Vida
Recuperação da Função Fisiológica
Factores de Tempo
Resultado de Tratamento
Bexiga
Urodinâmica
topic Artérias
Biópsia
Embolização Terapêutica
Efeitos Adversos
Estudos de Viabilidade
Isquemia
Ressonância Magnética
Tamanho do Órgão
Erecção do Pénis
Projectos Piloto
Álcool de Polivinil
Portugal
Estudos Prospectivos
Próstata
Ultrassonografia
Antigénio Prostático Específico
Hiperplasia Prostática
Qualidade de Vida
Recuperação da Função Fisiológica
Factores de Tempo
Resultado de Tratamento
Bexiga
Urodinâmica
description PURPOSE: To evaluate whether prostatic arterial embolization (PAE) might be a feasible procedure to treat lower urinary tract symptoms associated with benign prostatic hyperplasia (BPH). MATERIALS AND METHODS: Fifteen patients (age range, 62-82 years; mean age, 74.1 y) with symptomatic BPH after failure of medical treatment were selected for PAE with nonspherical 200-μm polyvinyl alcohol particles. The procedure was performed by a single femoral approach. Technical success was considered when selective prostatic arterial catheterization and embolization was achieved on at least one pelvic side. RESULTS: PAE was technically successful in 14 of the 15 patients (93.3%). There was a mean follow-up of 7.9 months (range, 3-12 months). International Prostate Symptom Score decreased a mean of 6.5 points (P = .005), quality of life improved 1.14 points (P = .065), International Index of Erectile Function increased 1.7 points (P = .063), and peak urinary flow increased 3.85 mL/sec (P = .015). There was a mean prostate-specific antigen reduction of 2.27 ng/mL (P = .072) and a mean prostate volume decrease of 26.5 mL (P = .0001) by ultrasound and 28.9 mL (P = .008) by magnetic resonance imaging. There was one major complication (a 1.5-cm(2) ischemic area of the bladder wall) and four clinical failures (28.6%). CONCLUSIONS: In this small group of patients, PAE was a feasible procedure, with preliminary results and short-term follow-up suggesting good symptom control without sexual dysfunction in suitable candidates, associated with a reduction in prostate volume.
publishDate 2011
dc.date.none.fl_str_mv 2011
2011-01-01T00:00:00Z
2013-03-27T17:21:26Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10400.17/1193
url http://hdl.handle.net/10400.17/1193
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv J Vasc Interv Radiol. 2011 Jan;22(1):11-9; quiz 20
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
repository.mail.fl_str_mv mluisa.alvim@gmail.com
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