Multiple Myeloma IgM – a clinical case report

Detalhes bibliográficos
Autor(a) principal: Santos, Bruno
Data de Publicação: 2006
Outros Autores: Arez, Luísa, Taveira, Teresa, Palma, Santos, Tomé, Rui
Tipo de documento: Artigo
Idioma: por
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: https://revista.spmi.pt/index.php/rpmi/article/view/1630
Resumo: The IgM monoclonal gammopathy can be associated with multiple pathologies namely lymphoproliferative conditions, multiple myeloma, solid tumours as well as benign conditions such as infections and monoclonal gammopathy of undetermined significance. The differential diagnosis is not always easy and it should follow clinical, laboratory and histopathologic criteria. To this purpose the authors present a clinical case of a 56-year-old male patient, with bone pain, located predominantly in the right shoulder. The association of multiple osteolytic lesions, monoclonal gammopathy IgMk and plasmocytic infi ltration seen on the bone marrow biopsy established the diagnosis of Multiple Myeloma IgMk.Theoretical considerations are discussed about this myeloma subtype, considered by some authors as an intermediate form between Waldenström’s Macroglobulinaemia and Multiple Myeloma.
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spelling Multiple Myeloma IgM – a clinical case reportMieloma múltiplo IgM – a propósito de um caso clínicoMieloma múltiploMacroglobulinemia de Waldenströmgamapatia monoclonalimunoglobulinaMultiple myelomaWaldenström’s Macroglobulinaemiamonoclonal gammopathyimmunoglobulinThe IgM monoclonal gammopathy can be associated with multiple pathologies namely lymphoproliferative conditions, multiple myeloma, solid tumours as well as benign conditions such as infections and monoclonal gammopathy of undetermined significance. The differential diagnosis is not always easy and it should follow clinical, laboratory and histopathologic criteria. To this purpose the authors present a clinical case of a 56-year-old male patient, with bone pain, located predominantly in the right shoulder. The association of multiple osteolytic lesions, monoclonal gammopathy IgMk and plasmocytic infi ltration seen on the bone marrow biopsy established the diagnosis of Multiple Myeloma IgMk.Theoretical considerations are discussed about this myeloma subtype, considered by some authors as an intermediate form between Waldenström’s Macroglobulinaemia and Multiple Myeloma.A gamapatia monoclonal IgM pode associar-se a múltiplas patologias, nomeadamente a neoplasias linfoproliferativas, ao mieloma múltiplo, a neoplasias sólidas e ainda a processos benignos, como as infecções e a gamapatia de significado indeterminado. O diagnóstico diferencial nem sempre é fácil e deve obedecer a critérios clínicos, laboratoriais e histopatológicos.A este propósito, os autores apresentam um caso clínico de um doente do sexo masculino, 56 anos, com dores ósseas, localizadas predominantemente no ombro direito. As múltiplas lesões líticas, associadas à gamapatia monoclonal IgMκ e à infi ltração plasmocitária na biopsia osteo-medular permitiram efectuar o diagnóstico de Mieloma Múltiplo IgMκ.Teceremos algumas considerações teóricas sobre este subtipo de mieloma considerado, por alguns autores, como uma forma intermédia entre Macroglobulinemia de Waldenström e Mieloma Múltiplo.Sociedade Portuguesa de Medicina Interna2006-06-30info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttps://revista.spmi.pt/index.php/rpmi/article/view/1630Internal Medicine; Vol. 13 No. 2 (2006): Abril/ Junho; 83-89Medicina Interna; Vol. 13 N.º 2 (2006): Abril/ Junho; 83-892183-99800872-671Xreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAPporhttps://revista.spmi.pt/index.php/rpmi/article/view/1630https://revista.spmi.pt/index.php/rpmi/article/view/1630/1097Santos, BrunoArez, LuísaTaveira, TeresaPalma, SantosTomé, Ruiinfo:eu-repo/semantics/openAccess2023-02-25T06:11:04Zoai:oai.revista.spmi.pt:article/1630Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T16:47:16.764094Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Multiple Myeloma IgM – a clinical case report
Mieloma múltiplo IgM – a propósito de um caso clínico
title Multiple Myeloma IgM – a clinical case report
spellingShingle Multiple Myeloma IgM – a clinical case report
Santos, Bruno
Mieloma múltiplo
Macroglobulinemia de Waldenström
gamapatia monoclonal
imunoglobulina
Multiple myeloma
Waldenström’s Macroglobulinaemia
monoclonal gammopathy
immunoglobulin
title_short Multiple Myeloma IgM – a clinical case report
title_full Multiple Myeloma IgM – a clinical case report
title_fullStr Multiple Myeloma IgM – a clinical case report
title_full_unstemmed Multiple Myeloma IgM – a clinical case report
title_sort Multiple Myeloma IgM – a clinical case report
author Santos, Bruno
author_facet Santos, Bruno
Arez, Luísa
Taveira, Teresa
Palma, Santos
Tomé, Rui
author_role author
author2 Arez, Luísa
Taveira, Teresa
Palma, Santos
Tomé, Rui
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Santos, Bruno
Arez, Luísa
Taveira, Teresa
Palma, Santos
Tomé, Rui
dc.subject.por.fl_str_mv Mieloma múltiplo
Macroglobulinemia de Waldenström
gamapatia monoclonal
imunoglobulina
Multiple myeloma
Waldenström’s Macroglobulinaemia
monoclonal gammopathy
immunoglobulin
topic Mieloma múltiplo
Macroglobulinemia de Waldenström
gamapatia monoclonal
imunoglobulina
Multiple myeloma
Waldenström’s Macroglobulinaemia
monoclonal gammopathy
immunoglobulin
description The IgM monoclonal gammopathy can be associated with multiple pathologies namely lymphoproliferative conditions, multiple myeloma, solid tumours as well as benign conditions such as infections and monoclonal gammopathy of undetermined significance. The differential diagnosis is not always easy and it should follow clinical, laboratory and histopathologic criteria. To this purpose the authors present a clinical case of a 56-year-old male patient, with bone pain, located predominantly in the right shoulder. The association of multiple osteolytic lesions, monoclonal gammopathy IgMk and plasmocytic infi ltration seen on the bone marrow biopsy established the diagnosis of Multiple Myeloma IgMk.Theoretical considerations are discussed about this myeloma subtype, considered by some authors as an intermediate form between Waldenström’s Macroglobulinaemia and Multiple Myeloma.
publishDate 2006
dc.date.none.fl_str_mv 2006-06-30
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://revista.spmi.pt/index.php/rpmi/article/view/1630
url https://revista.spmi.pt/index.php/rpmi/article/view/1630
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://revista.spmi.pt/index.php/rpmi/article/view/1630
https://revista.spmi.pt/index.php/rpmi/article/view/1630/1097
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Sociedade Portuguesa de Medicina Interna
publisher.none.fl_str_mv Sociedade Portuguesa de Medicina Interna
dc.source.none.fl_str_mv Internal Medicine; Vol. 13 No. 2 (2006): Abril/ Junho; 83-89
Medicina Interna; Vol. 13 N.º 2 (2006): Abril/ Junho; 83-89
2183-9980
0872-671X
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
repository.mail.fl_str_mv
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