The science of micronutrients in clinical practice – Report on the ESPEN symposium
Autor(a) principal: | |
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Data de Publicação: | 2024 |
Outros Autores: | , , , , , , , , , , , , , , , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10400.14/43474 |
Resumo: | Background & aims: The European Society for Clinical Nutrition and Metabolism published its first clinical guidelines for use of micronutrients (MNs) in 2022. A two-day web symposium was organized in November 2022 discussing how to apply the guidelines in clinical practice. The present paper reports the main findings of this symposium. Methods: Current evidence was discussed, the first day being devoted to clarifying the biology underlying the guidelines, especially regarding the definition of deficiency, the impact of inflammation, and the roles in antioxidant defences and immunity. The second day focused on clinical situations with high prevalence of MN depletion and deficiency. Results: The importance of the determination of MN status in patients at risk and diagnosis of deficiencies is still insufficiently perceived, considering the essential role of MNs in immune and antioxidant defences. Epidemiological data show that deficiencies of several MNs (iron, iodine, vitamin D) are a global problem that affects human health and well-being including immune responses such as to vaccination. Clinical conditions frequently associated with MN deficiencies were discussed including cancer, obesity with impact of bariatric surgery, diseases of the gastrointestinal tract, critical illness, and aging. In all these conditions, MN deficiency is associated with worsening of outcomes. The recurrent problem of shortage of MN products, but also lack of individual MN-products is a worldwide problem. Conclusion: Despite important progress in epidemiology and clinical nutrition, numerous gaps in practice persist. MN depletion and deficiency are frequently insufficiently searched for in clinical conditions, leading to inadequate treatment. The symposium concluded that more research and continued education are required to improve patient outcome. |
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The science of micronutrients in clinical practice – Report on the ESPEN symposiumDeficiencyEpidemiologyImmunityInflammationTrace elementVitaminBackground & aims: The European Society for Clinical Nutrition and Metabolism published its first clinical guidelines for use of micronutrients (MNs) in 2022. A two-day web symposium was organized in November 2022 discussing how to apply the guidelines in clinical practice. The present paper reports the main findings of this symposium. Methods: Current evidence was discussed, the first day being devoted to clarifying the biology underlying the guidelines, especially regarding the definition of deficiency, the impact of inflammation, and the roles in antioxidant defences and immunity. The second day focused on clinical situations with high prevalence of MN depletion and deficiency. Results: The importance of the determination of MN status in patients at risk and diagnosis of deficiencies is still insufficiently perceived, considering the essential role of MNs in immune and antioxidant defences. Epidemiological data show that deficiencies of several MNs (iron, iodine, vitamin D) are a global problem that affects human health and well-being including immune responses such as to vaccination. Clinical conditions frequently associated with MN deficiencies were discussed including cancer, obesity with impact of bariatric surgery, diseases of the gastrointestinal tract, critical illness, and aging. In all these conditions, MN deficiency is associated with worsening of outcomes. The recurrent problem of shortage of MN products, but also lack of individual MN-products is a worldwide problem. Conclusion: Despite important progress in epidemiology and clinical nutrition, numerous gaps in practice persist. MN depletion and deficiency are frequently insufficiently searched for in clinical conditions, leading to inadequate treatment. The symposium concluded that more research and continued education are required to improve patient outcome.Veritati - Repositório Institucional da Universidade Católica PortuguesaBerger, Mette M.Amrein, KarinBarazzoni, RoccoBindels, LaureBretón, IreneCalder, Philip C.Cappa, StefanoCuerda, CristinaD'Amelio, PatriziaMan, Angélique deDelzenne, Nathalie M.Forbes, AlastairGenton, LaurenceGombart, Adrian F.Joly, FranciscaLaviano, AlessandroMatthys, ChristophePhyo, Pyi PyiRavasco, PaulaSerlie, Mireille J.Shenkin, AlanStoffel, Nicole U.Talwar, DineshZanten, Arthur R. H. Van2024-01-03T17:35:39Z2024-012024-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.14/43474eng0261-561410.1016/j.clnu.2023.12.0068518032335738104489info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-01-09T01:37:36Zoai:repositorio.ucp.pt:10400.14/43474Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T01:30:52.420345Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
The science of micronutrients in clinical practice – Report on the ESPEN symposium |
title |
The science of micronutrients in clinical practice – Report on the ESPEN symposium |
spellingShingle |
The science of micronutrients in clinical practice – Report on the ESPEN symposium Berger, Mette M. Deficiency Epidemiology Immunity Inflammation Trace element Vitamin |
title_short |
The science of micronutrients in clinical practice – Report on the ESPEN symposium |
title_full |
The science of micronutrients in clinical practice – Report on the ESPEN symposium |
title_fullStr |
The science of micronutrients in clinical practice – Report on the ESPEN symposium |
title_full_unstemmed |
The science of micronutrients in clinical practice – Report on the ESPEN symposium |
title_sort |
The science of micronutrients in clinical practice – Report on the ESPEN symposium |
author |
Berger, Mette M. |
author_facet |
Berger, Mette M. Amrein, Karin Barazzoni, Rocco Bindels, Laure Bretón, Irene Calder, Philip C. Cappa, Stefano Cuerda, Cristina D'Amelio, Patrizia Man, Angélique de Delzenne, Nathalie M. Forbes, Alastair Genton, Laurence Gombart, Adrian F. Joly, Francisca Laviano, Alessandro Matthys, Christophe Phyo, Pyi Pyi Ravasco, Paula Serlie, Mireille J. Shenkin, Alan Stoffel, Nicole U. Talwar, Dinesh Zanten, Arthur R. H. Van |
author_role |
author |
author2 |
Amrein, Karin Barazzoni, Rocco Bindels, Laure Bretón, Irene Calder, Philip C. Cappa, Stefano Cuerda, Cristina D'Amelio, Patrizia Man, Angélique de Delzenne, Nathalie M. Forbes, Alastair Genton, Laurence Gombart, Adrian F. Joly, Francisca Laviano, Alessandro Matthys, Christophe Phyo, Pyi Pyi Ravasco, Paula Serlie, Mireille J. Shenkin, Alan Stoffel, Nicole U. Talwar, Dinesh Zanten, Arthur R. H. Van |
author2_role |
author author author author author author author author author author author author author author author author author author author author author author author |
dc.contributor.none.fl_str_mv |
Veritati - Repositório Institucional da Universidade Católica Portuguesa |
dc.contributor.author.fl_str_mv |
Berger, Mette M. Amrein, Karin Barazzoni, Rocco Bindels, Laure Bretón, Irene Calder, Philip C. Cappa, Stefano Cuerda, Cristina D'Amelio, Patrizia Man, Angélique de Delzenne, Nathalie M. Forbes, Alastair Genton, Laurence Gombart, Adrian F. Joly, Francisca Laviano, Alessandro Matthys, Christophe Phyo, Pyi Pyi Ravasco, Paula Serlie, Mireille J. Shenkin, Alan Stoffel, Nicole U. Talwar, Dinesh Zanten, Arthur R. H. Van |
dc.subject.por.fl_str_mv |
Deficiency Epidemiology Immunity Inflammation Trace element Vitamin |
topic |
Deficiency Epidemiology Immunity Inflammation Trace element Vitamin |
description |
Background & aims: The European Society for Clinical Nutrition and Metabolism published its first clinical guidelines for use of micronutrients (MNs) in 2022. A two-day web symposium was organized in November 2022 discussing how to apply the guidelines in clinical practice. The present paper reports the main findings of this symposium. Methods: Current evidence was discussed, the first day being devoted to clarifying the biology underlying the guidelines, especially regarding the definition of deficiency, the impact of inflammation, and the roles in antioxidant defences and immunity. The second day focused on clinical situations with high prevalence of MN depletion and deficiency. Results: The importance of the determination of MN status in patients at risk and diagnosis of deficiencies is still insufficiently perceived, considering the essential role of MNs in immune and antioxidant defences. Epidemiological data show that deficiencies of several MNs (iron, iodine, vitamin D) are a global problem that affects human health and well-being including immune responses such as to vaccination. Clinical conditions frequently associated with MN deficiencies were discussed including cancer, obesity with impact of bariatric surgery, diseases of the gastrointestinal tract, critical illness, and aging. In all these conditions, MN deficiency is associated with worsening of outcomes. The recurrent problem of shortage of MN products, but also lack of individual MN-products is a worldwide problem. Conclusion: Despite important progress in epidemiology and clinical nutrition, numerous gaps in practice persist. MN depletion and deficiency are frequently insufficiently searched for in clinical conditions, leading to inadequate treatment. The symposium concluded that more research and continued education are required to improve patient outcome. |
publishDate |
2024 |
dc.date.none.fl_str_mv |
2024-01-03T17:35:39Z 2024-01 2024-01-01T00:00:00Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10400.14/43474 |
url |
http://hdl.handle.net/10400.14/43474 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
0261-5614 10.1016/j.clnu.2023.12.006 85180323357 38104489 |
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info:eu-repo/semantics/openAccess |
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openAccess |
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application/pdf |
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