Persistent Leprosy Reaction 8 Years After the End of Therapy: Challenges for Doctors and Patients
Autor(a) principal: | |
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Data de Publicação: | 2020 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | https://doi.org/10.29021/spdv.77.4.1097 |
Resumo: | Introduction: In addition to infection with Mycobacterium leprae, type 1 and 2 reactions represent acute inflammatory events in the chronic course of multibacillary leprosy, which may persist for long periods. Case Report: A young woman presenting borderline lepromatous leprosy and persistent type 2 reaction with difficult clinical conduction. Discussion: The case illustrates the diagnostic challenge in leprosy with a systemic inflammatory response, more expressive than the dermato – neurological features. The clinical, histopathological and therapeutic implications, as well as risk factors for reaction and also polymerase chain reaction 8 years after being discharged from treatment of multidrug therapy are discussed. |
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Persistent Leprosy Reaction 8 Years After the End of Therapy: Challenges for Doctors and PatientsReação Hanseniásica Persistente 8 Anos Após Conclusão da Terapêutica: Desafio para Médicos e PacientesLeprosy/complicationsLeprosy/therapyPanniculitisLepra/complicaçõesLepra/tratamentoPaniculiteIntroduction: In addition to infection with Mycobacterium leprae, type 1 and 2 reactions represent acute inflammatory events in the chronic course of multibacillary leprosy, which may persist for long periods. Case Report: A young woman presenting borderline lepromatous leprosy and persistent type 2 reaction with difficult clinical conduction. Discussion: The case illustrates the diagnostic challenge in leprosy with a systemic inflammatory response, more expressive than the dermato – neurological features. The clinical, histopathological and therapeutic implications, as well as risk factors for reaction and also polymerase chain reaction 8 years after being discharged from treatment of multidrug therapy are discussed.Introdução: Para além da infecção pelo Mycobacterium leprae, as reações tipo 1 e 2 representam eventos inflama- tórios agudos, no curso crónico da hanseníase multibacilar, mas que podem ser recorrentes e tardias. Caso Clínico: Jovem com quadro de reação tipo 2 no contexto de hanseníase borderline lepromatosa, persistente e de difícil condução clínica. Discussão: O caso ilustra o desafio diagnóstico na hanseníase com resposta inflamatória sistémica, mais expressiva que o quadro dermato – neurológico. São discutidas as implicações clínicas, histopatológicas e terapêuticas, além de fatores de risco para reação e a positividade da reação em cadeia da polimerase 8 anos após a alta da poliquimioterapiaSociedade Portuguesa de Dermatologia e Venereologia2020-01-11T00:00:00Zjournal articleinfo:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://doi.org/10.29021/spdv.77.4.1097oai:ojs.revista.spdv.com.pt:article/1097Journal of the Portuguese Society of Dermatology and Venereology; Vol 77 No 4 (2019): October - December; 357-362Revista da Sociedade Portuguesa de Dermatologia e Venereologia; v. 77 n. 4 (2019): Outubro - Dezembro; 357-3622182-24092182-2395reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAPporhttps://revista.spdv.com.pt/index.php/spdv/article/view/1097https://doi.org/10.29021/spdv.77.4.1097https://revista.spdv.com.pt/index.php/spdv/article/view/1097/808Franco Ferraz Santino, MarianaCuzzi, TulliaManta, Fernanda Saloum de NevesOliveira, Maria Leide W.info:eu-repo/semantics/openAccess2022-10-06T12:35:12Zoai:ojs.revista.spdv.com.pt:article/1097Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T16:11:10.437481Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Persistent Leprosy Reaction 8 Years After the End of Therapy: Challenges for Doctors and Patients Reação Hanseniásica Persistente 8 Anos Após Conclusão da Terapêutica: Desafio para Médicos e Pacientes |
title |
Persistent Leprosy Reaction 8 Years After the End of Therapy: Challenges for Doctors and Patients |
spellingShingle |
Persistent Leprosy Reaction 8 Years After the End of Therapy: Challenges for Doctors and Patients Franco Ferraz Santino, Mariana Leprosy/complications Leprosy/therapy Panniculitis Lepra/complicações Lepra/tratamento Paniculite |
title_short |
Persistent Leprosy Reaction 8 Years After the End of Therapy: Challenges for Doctors and Patients |
title_full |
Persistent Leprosy Reaction 8 Years After the End of Therapy: Challenges for Doctors and Patients |
title_fullStr |
Persistent Leprosy Reaction 8 Years After the End of Therapy: Challenges for Doctors and Patients |
title_full_unstemmed |
Persistent Leprosy Reaction 8 Years After the End of Therapy: Challenges for Doctors and Patients |
title_sort |
Persistent Leprosy Reaction 8 Years After the End of Therapy: Challenges for Doctors and Patients |
author |
Franco Ferraz Santino, Mariana |
author_facet |
Franco Ferraz Santino, Mariana Cuzzi, Tullia Manta, Fernanda Saloum de Neves Oliveira, Maria Leide W. |
author_role |
author |
author2 |
Cuzzi, Tullia Manta, Fernanda Saloum de Neves Oliveira, Maria Leide W. |
author2_role |
author author author |
dc.contributor.author.fl_str_mv |
Franco Ferraz Santino, Mariana Cuzzi, Tullia Manta, Fernanda Saloum de Neves Oliveira, Maria Leide W. |
dc.subject.por.fl_str_mv |
Leprosy/complications Leprosy/therapy Panniculitis Lepra/complicações Lepra/tratamento Paniculite |
topic |
Leprosy/complications Leprosy/therapy Panniculitis Lepra/complicações Lepra/tratamento Paniculite |
description |
Introduction: In addition to infection with Mycobacterium leprae, type 1 and 2 reactions represent acute inflammatory events in the chronic course of multibacillary leprosy, which may persist for long periods. Case Report: A young woman presenting borderline lepromatous leprosy and persistent type 2 reaction with difficult clinical conduction. Discussion: The case illustrates the diagnostic challenge in leprosy with a systemic inflammatory response, more expressive than the dermato – neurological features. The clinical, histopathological and therapeutic implications, as well as risk factors for reaction and also polymerase chain reaction 8 years after being discharged from treatment of multidrug therapy are discussed. |
publishDate |
2020 |
dc.date.none.fl_str_mv |
2020-01-11T00:00:00Z |
dc.type.driver.fl_str_mv |
journal article info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://doi.org/10.29021/spdv.77.4.1097 oai:ojs.revista.spdv.com.pt:article/1097 |
url |
https://doi.org/10.29021/spdv.77.4.1097 |
identifier_str_mv |
oai:ojs.revista.spdv.com.pt:article/1097 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
https://revista.spdv.com.pt/index.php/spdv/article/view/1097 https://doi.org/10.29021/spdv.77.4.1097 https://revista.spdv.com.pt/index.php/spdv/article/view/1097/808 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Sociedade Portuguesa de Dermatologia e Venereologia |
publisher.none.fl_str_mv |
Sociedade Portuguesa de Dermatologia e Venereologia |
dc.source.none.fl_str_mv |
Journal of the Portuguese Society of Dermatology and Venereology; Vol 77 No 4 (2019): October - December; 357-362 Revista da Sociedade Portuguesa de Dermatologia e Venereologia; v. 77 n. 4 (2019): Outubro - Dezembro; 357-362 2182-2409 2182-2395 reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
instname_str |
Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
instacron_str |
RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
repository.mail.fl_str_mv |
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