A safety assessment of Coriolus versicolor biomass as a food supplement

Detalhes bibliográficos
Autor(a) principal: Barros, AB
Data de Publicação: 2016
Outros Autores: Ferrão, Jorge, Fernandes, Tito
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: https://doi.org/10.3402/fnr.v60.29953
Resumo: Background: Coriolus versicolor (CV) is a common mushroom with antitumor, anti-inflammatory, antioxidant, antiviral, antibacterial, and immunomodulatory properties. The existence of these properties has been extensively proven mainly using CV extract; research on the biomass form is scarce. Objective: The aim of this study was to investigate the safety of the CV biomass form, as it is commonly used as a food supplement. Design: CV biomass powder was dissolved in distilled water and administered daily (2.5, 5.0, and 7.5 g/kg live weight) in single doses by gavage to both female and male Charles River albino rats. Results: No adverse or lethal effects were observed as a consequence of the daily administration of CV biomass. In addition, compared with the control group, no abnormal findings were observed at necropsy and histopathological examination. Conclusions: A safe profile of CV biomass for human consumption can be inferred from the absence of any remarkable adverse effects in rats.
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spelling A safety assessment of Coriolus versicolor biomass as a food supplementBiomassCoriolus versicolorFood supplementMushroomsSafety assessmentFood ScienceNutrition and DieteticsPublic Health, Environmental and Occupational HealthSDG 3 - Good Health and Well-beingBackground: Coriolus versicolor (CV) is a common mushroom with antitumor, anti-inflammatory, antioxidant, antiviral, antibacterial, and immunomodulatory properties. The existence of these properties has been extensively proven mainly using CV extract; research on the biomass form is scarce. Objective: The aim of this study was to investigate the safety of the CV biomass form, as it is commonly used as a food supplement. Design: CV biomass powder was dissolved in distilled water and administered daily (2.5, 5.0, and 7.5 g/kg live weight) in single doses by gavage to both female and male Charles River albino rats. Results: No adverse or lethal effects were observed as a consequence of the daily administration of CV biomass. In addition, compared with the control group, no abnormal findings were observed at necropsy and histopathological examination. Conclusions: A safe profile of CV biomass for human consumption can be inferred from the absence of any remarkable adverse effects in rats.Instituto de Higiene e Medicina Tropical (IHMT)RUNBarros, ABFerrão, JorgeFernandes, Tito2018-05-11T22:05:35Z2016-03-102016-03-10T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttps://doi.org/10.3402/fnr.v60.29953eng1654-6628PURE: 2442717http://www.scopus.com/inward/record.url?scp=84962287779&partnerID=8YFLogxKhttps://doi.org/10.3402/fnr.v60.29953info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-03-11T04:20:07Zoai:run.unl.pt:10362/36629Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T03:30:36.006221Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv A safety assessment of Coriolus versicolor biomass as a food supplement
title A safety assessment of Coriolus versicolor biomass as a food supplement
spellingShingle A safety assessment of Coriolus versicolor biomass as a food supplement
Barros, AB
Biomass
Coriolus versicolor
Food supplement
Mushrooms
Safety assessment
Food Science
Nutrition and Dietetics
Public Health, Environmental and Occupational Health
SDG 3 - Good Health and Well-being
title_short A safety assessment of Coriolus versicolor biomass as a food supplement
title_full A safety assessment of Coriolus versicolor biomass as a food supplement
title_fullStr A safety assessment of Coriolus versicolor biomass as a food supplement
title_full_unstemmed A safety assessment of Coriolus versicolor biomass as a food supplement
title_sort A safety assessment of Coriolus versicolor biomass as a food supplement
author Barros, AB
author_facet Barros, AB
Ferrão, Jorge
Fernandes, Tito
author_role author
author2 Ferrão, Jorge
Fernandes, Tito
author2_role author
author
dc.contributor.none.fl_str_mv Instituto de Higiene e Medicina Tropical (IHMT)
RUN
dc.contributor.author.fl_str_mv Barros, AB
Ferrão, Jorge
Fernandes, Tito
dc.subject.por.fl_str_mv Biomass
Coriolus versicolor
Food supplement
Mushrooms
Safety assessment
Food Science
Nutrition and Dietetics
Public Health, Environmental and Occupational Health
SDG 3 - Good Health and Well-being
topic Biomass
Coriolus versicolor
Food supplement
Mushrooms
Safety assessment
Food Science
Nutrition and Dietetics
Public Health, Environmental and Occupational Health
SDG 3 - Good Health and Well-being
description Background: Coriolus versicolor (CV) is a common mushroom with antitumor, anti-inflammatory, antioxidant, antiviral, antibacterial, and immunomodulatory properties. The existence of these properties has been extensively proven mainly using CV extract; research on the biomass form is scarce. Objective: The aim of this study was to investigate the safety of the CV biomass form, as it is commonly used as a food supplement. Design: CV biomass powder was dissolved in distilled water and administered daily (2.5, 5.0, and 7.5 g/kg live weight) in single doses by gavage to both female and male Charles River albino rats. Results: No adverse or lethal effects were observed as a consequence of the daily administration of CV biomass. In addition, compared with the control group, no abnormal findings were observed at necropsy and histopathological examination. Conclusions: A safe profile of CV biomass for human consumption can be inferred from the absence of any remarkable adverse effects in rats.
publishDate 2016
dc.date.none.fl_str_mv 2016-03-10
2016-03-10T00:00:00Z
2018-05-11T22:05:35Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://doi.org/10.3402/fnr.v60.29953
url https://doi.org/10.3402/fnr.v60.29953
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 1654-6628
PURE: 2442717
http://www.scopus.com/inward/record.url?scp=84962287779&partnerID=8YFLogxK
https://doi.org/10.3402/fnr.v60.29953
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
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reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
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