Protein Nanocarriers for Targeted Drug Delivery for Cancer Therapy
Autor(a) principal: | |
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Data de Publicação: | 2019 |
Outros Autores: | , , |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10400.8/8615 |
Resumo: | This chapter describes how proteins can be used to provide effective targeted nanocarriers for drugs to target tumors. This approach offers an exciting framework for cancer therapies in the future, allowing multiple therapeutic agents and other functions to be combined in the same particle and ensuring a lower toxicity for the patient. The use of proteins provides a rich library of functional molecules to exploit in this methodology. The role of computer simulation to identify the best combination of protein, ligand, and drugs is highlighted. |
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Protein Nanocarriers for Targeted Drug Delivery for Cancer TherapyCancer therapyDrug deliveryNanoparticlesProteinsTargeted deliveryThis chapter describes how proteins can be used to provide effective targeted nanocarriers for drugs to target tumors. This approach offers an exciting framework for cancer therapies in the future, allowing multiple therapeutic agents and other functions to be combined in the same particle and ensuring a lower toxicity for the patient. The use of proteins provides a rich library of functional molecules to exploit in this methodology. The role of computer simulation to identify the best combination of protein, ligand, and drugs is highlighted.ElsevierIC-OnlineKariduraganavar, Mahadevappa Y.Heggannavar, Geetha B.Amado, SandraMitchell, Geoffrey R.2023-06-21T11:20:07Z20192019-01-01T00:00:00Zbook partinfo:eu-repo/semantics/publishedVersionapplication/pdfhttp://hdl.handle.net/10400.8/8615engMahadevappa Y. Kariduraganavar, Geetha B. Heggannavar, Sandra Amado, Geoffrey R. Mitchell, Chapter 6 - Protein Nanocarriers for Targeted Drug Delivery for Cancer Therapy, Editor(s): Shyam S. Mohapatra, Shivendu Ranjan, Nandita Dasgupta, Raghvendra Kumar Mishra, Sabu Thomas, In Micro and Nano Technologies, Nanocarriers for Drug Delivery, Elsevier, 2019, Pages 173-204, ISBN 9780128140338, https://doi.org/10.1016/B978-0-12-814033-8.00006-09780128140338https://doi.org/10.1016/B978-0-12-814033-8.00006-0.info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-09-26T18:25:55Zoai:iconline.ipleiria.pt:10400.8/8615Portal AgregadorONGhttps://www.rcaap.pt/oai/openairemluisa.alvim@gmail.comopendoar:71602024-09-26T18:25:55Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Protein Nanocarriers for Targeted Drug Delivery for Cancer Therapy |
title |
Protein Nanocarriers for Targeted Drug Delivery for Cancer Therapy |
spellingShingle |
Protein Nanocarriers for Targeted Drug Delivery for Cancer Therapy Kariduraganavar, Mahadevappa Y. Cancer therapy Drug delivery Nanoparticles Proteins Targeted delivery |
title_short |
Protein Nanocarriers for Targeted Drug Delivery for Cancer Therapy |
title_full |
Protein Nanocarriers for Targeted Drug Delivery for Cancer Therapy |
title_fullStr |
Protein Nanocarriers for Targeted Drug Delivery for Cancer Therapy |
title_full_unstemmed |
Protein Nanocarriers for Targeted Drug Delivery for Cancer Therapy |
title_sort |
Protein Nanocarriers for Targeted Drug Delivery for Cancer Therapy |
author |
Kariduraganavar, Mahadevappa Y. |
author_facet |
Kariduraganavar, Mahadevappa Y. Heggannavar, Geetha B. Amado, Sandra Mitchell, Geoffrey R. |
author_role |
author |
author2 |
Heggannavar, Geetha B. Amado, Sandra Mitchell, Geoffrey R. |
author2_role |
author author author |
dc.contributor.none.fl_str_mv |
IC-Online |
dc.contributor.author.fl_str_mv |
Kariduraganavar, Mahadevappa Y. Heggannavar, Geetha B. Amado, Sandra Mitchell, Geoffrey R. |
dc.subject.por.fl_str_mv |
Cancer therapy Drug delivery Nanoparticles Proteins Targeted delivery |
topic |
Cancer therapy Drug delivery Nanoparticles Proteins Targeted delivery |
description |
This chapter describes how proteins can be used to provide effective targeted nanocarriers for drugs to target tumors. This approach offers an exciting framework for cancer therapies in the future, allowing multiple therapeutic agents and other functions to be combined in the same particle and ensuring a lower toxicity for the patient. The use of proteins provides a rich library of functional molecules to exploit in this methodology. The role of computer simulation to identify the best combination of protein, ligand, and drugs is highlighted. |
publishDate |
2019 |
dc.date.none.fl_str_mv |
2019 2019-01-01T00:00:00Z 2023-06-21T11:20:07Z |
dc.type.driver.fl_str_mv |
book part |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10400.8/8615 |
url |
http://hdl.handle.net/10400.8/8615 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Mahadevappa Y. Kariduraganavar, Geetha B. Heggannavar, Sandra Amado, Geoffrey R. Mitchell, Chapter 6 - Protein Nanocarriers for Targeted Drug Delivery for Cancer Therapy, Editor(s): Shyam S. Mohapatra, Shivendu Ranjan, Nandita Dasgupta, Raghvendra Kumar Mishra, Sabu Thomas, In Micro and Nano Technologies, Nanocarriers for Drug Delivery, Elsevier, 2019, Pages 173-204, ISBN 9780128140338, https://doi.org/10.1016/B978-0-12-814033-8.00006-0 9780128140338 https://doi.org/10.1016/B978-0-12-814033-8.00006-0. |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Elsevier |
publisher.none.fl_str_mv |
Elsevier |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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RCAAP |
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RCAAP |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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mluisa.alvim@gmail.com |
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1817547293180559360 |