Bone marrow transplantation. Preliminary results.

Detalhes bibliográficos
Autor(a) principal: Pimentel, P
Data de Publicação: 1991
Outros Autores: de Lacerda, J M
Tipo de documento: Artigo
Idioma: por
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/4480
Resumo: From May 1989 to March 1991 60 bone marrow transplants were performed--41 allogeneic and 19 autologous--in patients with malignant and nonmalignant hemopathies and solid tumors. The transplant related mortality was 19.4% and 10.5% for allografts and autografts, respectively. The projected relapse free survival at 22 months in patients with malignant hemopathies who underwent allotransplantation in early phase was 81% and, in patients in advanced phase 21.4% (p less than 0.001). In patients with aplastic anemia the actuarial survival at 22 months is 60%. In autografted patients, only one failed to have full engraftment and is dependent on platelet support at day 79. Follow-up in all autografts is less than one year. These preliminary results of our bone marrow transplant program show low morbidity and mortality related to transplantation and suggest significant therapeutic effect.
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spelling Bone marrow transplantation. Preliminary results.Transplantação da medula óssea. Resultados preliminares.From May 1989 to March 1991 60 bone marrow transplants were performed--41 allogeneic and 19 autologous--in patients with malignant and nonmalignant hemopathies and solid tumors. The transplant related mortality was 19.4% and 10.5% for allografts and autografts, respectively. The projected relapse free survival at 22 months in patients with malignant hemopathies who underwent allotransplantation in early phase was 81% and, in patients in advanced phase 21.4% (p less than 0.001). In patients with aplastic anemia the actuarial survival at 22 months is 60%. In autografted patients, only one failed to have full engraftment and is dependent on platelet support at day 79. Follow-up in all autografts is less than one year. These preliminary results of our bone marrow transplant program show low morbidity and mortality related to transplantation and suggest significant therapeutic effect.From May 1989 to March 1991 60 bone marrow transplants were performed--41 allogeneic and 19 autologous--in patients with malignant and nonmalignant hemopathies and solid tumors. The transplant related mortality was 19.4% and 10.5% for allografts and autografts, respectively. The projected relapse free survival at 22 months in patients with malignant hemopathies who underwent allotransplantation in early phase was 81% and, in patients in advanced phase 21.4% (p less than 0.001). In patients with aplastic anemia the actuarial survival at 22 months is 60%. In autografted patients, only one failed to have full engraftment and is dependent on platelet support at day 79. Follow-up in all autografts is less than one year. These preliminary results of our bone marrow transplant program show low morbidity and mortality related to transplantation and suggest significant therapeutic effect.Ordem dos Médicos1991-12-31info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttps://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/4480oai:ojs.www.actamedicaportuguesa.com:article/4480Acta Médica Portuguesa; Vol. 4 (1991): Suplemento 4; 39S-43SActa Médica Portuguesa; Vol. 4 (1991): Suplemento 4; 39S-43S1646-07580870-399Xreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAPporhttps://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/4480https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/4480/3507Pimentel, Pde Lacerda, J Minfo:eu-repo/semantics/openAccess2022-12-20T11:03:42Zoai:ojs.www.actamedicaportuguesa.com:article/4480Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T16:18:52.261023Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Bone marrow transplantation. Preliminary results.
Transplantação da medula óssea. Resultados preliminares.
title Bone marrow transplantation. Preliminary results.
spellingShingle Bone marrow transplantation. Preliminary results.
Pimentel, P
title_short Bone marrow transplantation. Preliminary results.
title_full Bone marrow transplantation. Preliminary results.
title_fullStr Bone marrow transplantation. Preliminary results.
title_full_unstemmed Bone marrow transplantation. Preliminary results.
title_sort Bone marrow transplantation. Preliminary results.
author Pimentel, P
author_facet Pimentel, P
de Lacerda, J M
author_role author
author2 de Lacerda, J M
author2_role author
dc.contributor.author.fl_str_mv Pimentel, P
de Lacerda, J M
description From May 1989 to March 1991 60 bone marrow transplants were performed--41 allogeneic and 19 autologous--in patients with malignant and nonmalignant hemopathies and solid tumors. The transplant related mortality was 19.4% and 10.5% for allografts and autografts, respectively. The projected relapse free survival at 22 months in patients with malignant hemopathies who underwent allotransplantation in early phase was 81% and, in patients in advanced phase 21.4% (p less than 0.001). In patients with aplastic anemia the actuarial survival at 22 months is 60%. In autografted patients, only one failed to have full engraftment and is dependent on platelet support at day 79. Follow-up in all autografts is less than one year. These preliminary results of our bone marrow transplant program show low morbidity and mortality related to transplantation and suggest significant therapeutic effect.
publishDate 1991
dc.date.none.fl_str_mv 1991-12-31
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dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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url https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/4480
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dc.language.iso.fl_str_mv por
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dc.relation.none.fl_str_mv https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/4480
https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/4480/3507
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dc.publisher.none.fl_str_mv Ordem dos Médicos
publisher.none.fl_str_mv Ordem dos Médicos
dc.source.none.fl_str_mv Acta Médica Portuguesa; Vol. 4 (1991): Suplemento 4; 39S-43S
Acta Médica Portuguesa; Vol. 4 (1991): Suplemento 4; 39S-43S
1646-0758
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