Aplastic anemia. Alternative treatment by bone marrow transplantation.

Detalhes bibliográficos
Autor(a) principal: Fonseca, T
Data de Publicação: 1997
Outros Autores: Raposo, J, Gomez, B, d'Oliveira, J J, de Lacerda, J M
Tipo de documento: Artigo
Idioma: por
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/2372
Resumo: We report a case of a 25-year-old woman, with the diagnosis of severe aplastic anemia without a histocompatible sibling donor for bone marrow transplantation. The patient has been treated successfully with a combination of two immunosuppressive agents, cyclosporine and antilymphocyte globulin, after not responding to primary therapy with corticosteroids and growth factors. She showed a complete response to treatment, with transfusional independence, after a follow-up of 14 months. The pathophysiology of aplastic anemia, the mechanism of action and secondary effects of these treatments are discussed.
id RCAP_b123deb1f889e6adb8750defa532d95a
oai_identifier_str oai:ojs.www.actamedicaportuguesa.com:article/2372
network_acronym_str RCAP
network_name_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository_id_str 7160
spelling Aplastic anemia. Alternative treatment by bone marrow transplantation.Anemia aplástica. Tratamento alternativo à transplantação medular.We report a case of a 25-year-old woman, with the diagnosis of severe aplastic anemia without a histocompatible sibling donor for bone marrow transplantation. The patient has been treated successfully with a combination of two immunosuppressive agents, cyclosporine and antilymphocyte globulin, after not responding to primary therapy with corticosteroids and growth factors. She showed a complete response to treatment, with transfusional independence, after a follow-up of 14 months. The pathophysiology of aplastic anemia, the mechanism of action and secondary effects of these treatments are discussed.We report a case of a 25-year-old woman, with the diagnosis of severe aplastic anemia without a histocompatible sibling donor for bone marrow transplantation. The patient has been treated successfully with a combination of two immunosuppressive agents, cyclosporine and antilymphocyte globulin, after not responding to primary therapy with corticosteroids and growth factors. She showed a complete response to treatment, with transfusional independence, after a follow-up of 14 months. The pathophysiology of aplastic anemia, the mechanism of action and secondary effects of these treatments are discussed.Ordem dos Médicos1997-01-30info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttps://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/2372oai:ojs.www.actamedicaportuguesa.com:article/2372Acta Médica Portuguesa; Vol. 10 No. 1 (1997): Janeiro; 99-102Acta Médica Portuguesa; Vol. 10 N.º 1 (1997): Janeiro; 99-1021646-07580870-399Xreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAPporhttps://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/2372https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/2372/1787Fonseca, TRaposo, JGomez, Bd'Oliveira, J Jde Lacerda, J Minfo:eu-repo/semantics/openAccess2022-12-20T11:00:24Zoai:ojs.www.actamedicaportuguesa.com:article/2372Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T16:17:42.188695Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Aplastic anemia. Alternative treatment by bone marrow transplantation.
Anemia aplástica. Tratamento alternativo à transplantação medular.
title Aplastic anemia. Alternative treatment by bone marrow transplantation.
spellingShingle Aplastic anemia. Alternative treatment by bone marrow transplantation.
Fonseca, T
title_short Aplastic anemia. Alternative treatment by bone marrow transplantation.
title_full Aplastic anemia. Alternative treatment by bone marrow transplantation.
title_fullStr Aplastic anemia. Alternative treatment by bone marrow transplantation.
title_full_unstemmed Aplastic anemia. Alternative treatment by bone marrow transplantation.
title_sort Aplastic anemia. Alternative treatment by bone marrow transplantation.
author Fonseca, T
author_facet Fonseca, T
Raposo, J
Gomez, B
d'Oliveira, J J
de Lacerda, J M
author_role author
author2 Raposo, J
Gomez, B
d'Oliveira, J J
de Lacerda, J M
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Fonseca, T
Raposo, J
Gomez, B
d'Oliveira, J J
de Lacerda, J M
description We report a case of a 25-year-old woman, with the diagnosis of severe aplastic anemia without a histocompatible sibling donor for bone marrow transplantation. The patient has been treated successfully with a combination of two immunosuppressive agents, cyclosporine and antilymphocyte globulin, after not responding to primary therapy with corticosteroids and growth factors. She showed a complete response to treatment, with transfusional independence, after a follow-up of 14 months. The pathophysiology of aplastic anemia, the mechanism of action and secondary effects of these treatments are discussed.
publishDate 1997
dc.date.none.fl_str_mv 1997-01-30
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/2372
oai:ojs.www.actamedicaportuguesa.com:article/2372
url https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/2372
identifier_str_mv oai:ojs.www.actamedicaportuguesa.com:article/2372
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/2372
https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/2372/1787
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Ordem dos Médicos
publisher.none.fl_str_mv Ordem dos Médicos
dc.source.none.fl_str_mv Acta Médica Portuguesa; Vol. 10 No. 1 (1997): Janeiro; 99-102
Acta Médica Portuguesa; Vol. 10 N.º 1 (1997): Janeiro; 99-102
1646-0758
0870-399X
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
repository.mail.fl_str_mv
_version_ 1799130630050545664

Registros relacionados