Protein analysis and gene expression indicate differential vulnerability of Iberian fish species under a climate change scenario

Detalhes bibliográficos
Autor(a) principal: Jesus, Tiago F.
Data de Publicação: 2017
Outros Autores: Moreno, João M., Repolho, Tiago, Athanasiadis, Alekos, Rosa, Rui, Almeida-Val, Vera M. F., Coelho, Maria M.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10400.7/779
Resumo: This deposit is composed by the main article plus the supplementary materials of the publication.
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spelling Protein analysis and gene expression indicate differential vulnerability of Iberian fish species under a climate change scenarioGene expressionClimate changeFreshwater fishEnergy metabolismHeat shock responseProtein foldingCircadian rhythmsProtein structure predictionThis deposit is composed by the main article plus the supplementary materials of the publication.Current knowledge on the biological responses of freshwater fish under projected scenarios of climate change remains limited. Here, we examine differences in the protein configuration of two endemic Iberian freshwater fish species, Squalius carolitertii and the critically endangered S. torgalensis that inhabit in the Atlantic-type northern and in the Mediterranean-type southwestern regions, respectively. We performed protein structure modeling of fourteen genes linked to protein folding, energy metabolism, circadian rhythms and immune responses. Structural differences in proteins between the two species were found for HSC70, FKBP52, HIF1α and GPB1. For S. torgalensis, besides structural differences, we found higher thermostability for two proteins (HSP90 and GBP1), which can be advantageous in a warmer environment. Additionally, we investigated how these species might respond to projected scenarios of 3° climate change warming, acidification (ΔpH = -0.4), and their combined effects. Significant changes in gene expression were observed in response to all treatments, particularly under the combined warming and acidification. While S. carolitertii presented changes in gene expression for multiple proteins related to folding (hsp90aa1, hsc70, fkbp4 and stip1), only one such gene was altered in S. torgalensis (stip1). However, S. torgalensis showed a greater capacity for energy production under both the acidification and combined scenarios by increasing cs gene expression and maintaining ldha gene expression in muscle. Overall, these findings suggest that S. torgalensis is better prepared to cope with projected climate change. Worryingly, under the simulated scenarios, disturbances to circadian rhythm and immune system genes (cry1aa, per1a and gbp1) raise concerns for the persistence of both species, highlighting the need to consider multi-stressor effects when evaluating climate change impacts upon fish. This work also highlights that assessments of the potential of endangered freshwater species to cope with environmental change are crucial to help decision-makers adopt future conservation strategies.Instituto da Conservação da Natureza e Florestas.Public Library of ScienceARCAJesus, Tiago F.Moreno, João M.Repolho, TiagoAthanasiadis, AlekosRosa, RuiAlmeida-Val, Vera M. F.Coelho, Maria M.2017-07-25T16:39:56Z2017-07-182017-07-18T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfapplication/vnd.openxmlformats-officedocument.wordprocessingml.documentapplication/pdfapplication/vnd.openxmlformats-officedocument.wordprocessingml.documentapplication/pdfapplication/vnd.openxmlformats-officedocument.wordprocessingml.documentapplication/vnd.openxmlformats-officedocument.spreadsheetml.sheetapplication/vnd.openxmlformats-officedocument.wordprocessingml.documenthttp://hdl.handle.net/10400.7/779engJesus TF, Moreno JM, Repolho T, Athanasiadis A, Rosa R, Almeida-Val VMF, et al. (2017) Protein analysis and gene expression indicate differential vulnerability of Iberian fish species under a climate change scenario. PLoS ONE 12(7): e0181325. https://doi.org/10.1371/journal.pone.018132510.1371/journal.pone.0181325info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2022-11-29T14:35:11Zoai:arca.igc.gulbenkian.pt:10400.7/779Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T16:12:00.358773Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Protein analysis and gene expression indicate differential vulnerability of Iberian fish species under a climate change scenario
title Protein analysis and gene expression indicate differential vulnerability of Iberian fish species under a climate change scenario
spellingShingle Protein analysis and gene expression indicate differential vulnerability of Iberian fish species under a climate change scenario
Jesus, Tiago F.
Gene expression
Climate change
Freshwater fish
Energy metabolism
Heat shock response
Protein folding
Circadian rhythms
Protein structure prediction
title_short Protein analysis and gene expression indicate differential vulnerability of Iberian fish species under a climate change scenario
title_full Protein analysis and gene expression indicate differential vulnerability of Iberian fish species under a climate change scenario
title_fullStr Protein analysis and gene expression indicate differential vulnerability of Iberian fish species under a climate change scenario
title_full_unstemmed Protein analysis and gene expression indicate differential vulnerability of Iberian fish species under a climate change scenario
title_sort Protein analysis and gene expression indicate differential vulnerability of Iberian fish species under a climate change scenario
author Jesus, Tiago F.
author_facet Jesus, Tiago F.
Moreno, João M.
Repolho, Tiago
Athanasiadis, Alekos
Rosa, Rui
Almeida-Val, Vera M. F.
Coelho, Maria M.
author_role author
author2 Moreno, João M.
Repolho, Tiago
Athanasiadis, Alekos
Rosa, Rui
Almeida-Val, Vera M. F.
Coelho, Maria M.
author2_role author
author
author
author
author
author
dc.contributor.none.fl_str_mv ARCA
dc.contributor.author.fl_str_mv Jesus, Tiago F.
Moreno, João M.
Repolho, Tiago
Athanasiadis, Alekos
Rosa, Rui
Almeida-Val, Vera M. F.
Coelho, Maria M.
dc.subject.por.fl_str_mv Gene expression
Climate change
Freshwater fish
Energy metabolism
Heat shock response
Protein folding
Circadian rhythms
Protein structure prediction
topic Gene expression
Climate change
Freshwater fish
Energy metabolism
Heat shock response
Protein folding
Circadian rhythms
Protein structure prediction
description This deposit is composed by the main article plus the supplementary materials of the publication.
publishDate 2017
dc.date.none.fl_str_mv 2017-07-25T16:39:56Z
2017-07-18
2017-07-18T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10400.7/779
url http://hdl.handle.net/10400.7/779
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Jesus TF, Moreno JM, Repolho T, Athanasiadis A, Rosa R, Almeida-Val VMF, et al. (2017) Protein analysis and gene expression indicate differential vulnerability of Iberian fish species under a climate change scenario. PLoS ONE 12(7): e0181325. https://doi.org/10.1371/journal.pone.0181325
10.1371/journal.pone.0181325
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
application/vnd.openxmlformats-officedocument.wordprocessingml.document
application/pdf
application/vnd.openxmlformats-officedocument.wordprocessingml.document
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application/vnd.openxmlformats-officedocument.spreadsheetml.sheet
application/vnd.openxmlformats-officedocument.wordprocessingml.document
dc.publisher.none.fl_str_mv Public Library of Science
publisher.none.fl_str_mv Public Library of Science
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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