Protein analysis and gene expression indicate differential vulnerability of Iberian fish species under a climate change scenario
Autor(a) principal: | |
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Data de Publicação: | 2017 |
Outros Autores: | , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10400.7/779 |
Resumo: | This deposit is composed by the main article plus the supplementary materials of the publication. |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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7160 |
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Protein analysis and gene expression indicate differential vulnerability of Iberian fish species under a climate change scenarioGene expressionClimate changeFreshwater fishEnergy metabolismHeat shock responseProtein foldingCircadian rhythmsProtein structure predictionThis deposit is composed by the main article plus the supplementary materials of the publication.Current knowledge on the biological responses of freshwater fish under projected scenarios of climate change remains limited. Here, we examine differences in the protein configuration of two endemic Iberian freshwater fish species, Squalius carolitertii and the critically endangered S. torgalensis that inhabit in the Atlantic-type northern and in the Mediterranean-type southwestern regions, respectively. We performed protein structure modeling of fourteen genes linked to protein folding, energy metabolism, circadian rhythms and immune responses. Structural differences in proteins between the two species were found for HSC70, FKBP52, HIF1α and GPB1. For S. torgalensis, besides structural differences, we found higher thermostability for two proteins (HSP90 and GBP1), which can be advantageous in a warmer environment. Additionally, we investigated how these species might respond to projected scenarios of 3° climate change warming, acidification (ΔpH = -0.4), and their combined effects. Significant changes in gene expression were observed in response to all treatments, particularly under the combined warming and acidification. While S. carolitertii presented changes in gene expression for multiple proteins related to folding (hsp90aa1, hsc70, fkbp4 and stip1), only one such gene was altered in S. torgalensis (stip1). However, S. torgalensis showed a greater capacity for energy production under both the acidification and combined scenarios by increasing cs gene expression and maintaining ldha gene expression in muscle. Overall, these findings suggest that S. torgalensis is better prepared to cope with projected climate change. Worryingly, under the simulated scenarios, disturbances to circadian rhythm and immune system genes (cry1aa, per1a and gbp1) raise concerns for the persistence of both species, highlighting the need to consider multi-stressor effects when evaluating climate change impacts upon fish. This work also highlights that assessments of the potential of endangered freshwater species to cope with environmental change are crucial to help decision-makers adopt future conservation strategies.Instituto da Conservação da Natureza e Florestas.Public Library of ScienceARCAJesus, Tiago F.Moreno, João M.Repolho, TiagoAthanasiadis, AlekosRosa, RuiAlmeida-Val, Vera M. F.Coelho, Maria M.2017-07-25T16:39:56Z2017-07-182017-07-18T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfapplication/vnd.openxmlformats-officedocument.wordprocessingml.documentapplication/pdfapplication/vnd.openxmlformats-officedocument.wordprocessingml.documentapplication/pdfapplication/vnd.openxmlformats-officedocument.wordprocessingml.documentapplication/vnd.openxmlformats-officedocument.spreadsheetml.sheetapplication/vnd.openxmlformats-officedocument.wordprocessingml.documenthttp://hdl.handle.net/10400.7/779engJesus TF, Moreno JM, Repolho T, Athanasiadis A, Rosa R, Almeida-Val VMF, et al. (2017) Protein analysis and gene expression indicate differential vulnerability of Iberian fish species under a climate change scenario. PLoS ONE 12(7): e0181325. https://doi.org/10.1371/journal.pone.018132510.1371/journal.pone.0181325info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2022-11-29T14:35:11Zoai:arca.igc.gulbenkian.pt:10400.7/779Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T16:12:00.358773Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Protein analysis and gene expression indicate differential vulnerability of Iberian fish species under a climate change scenario |
title |
Protein analysis and gene expression indicate differential vulnerability of Iberian fish species under a climate change scenario |
spellingShingle |
Protein analysis and gene expression indicate differential vulnerability of Iberian fish species under a climate change scenario Jesus, Tiago F. Gene expression Climate change Freshwater fish Energy metabolism Heat shock response Protein folding Circadian rhythms Protein structure prediction |
title_short |
Protein analysis and gene expression indicate differential vulnerability of Iberian fish species under a climate change scenario |
title_full |
Protein analysis and gene expression indicate differential vulnerability of Iberian fish species under a climate change scenario |
title_fullStr |
Protein analysis and gene expression indicate differential vulnerability of Iberian fish species under a climate change scenario |
title_full_unstemmed |
Protein analysis and gene expression indicate differential vulnerability of Iberian fish species under a climate change scenario |
title_sort |
Protein analysis and gene expression indicate differential vulnerability of Iberian fish species under a climate change scenario |
author |
Jesus, Tiago F. |
author_facet |
Jesus, Tiago F. Moreno, João M. Repolho, Tiago Athanasiadis, Alekos Rosa, Rui Almeida-Val, Vera M. F. Coelho, Maria M. |
author_role |
author |
author2 |
Moreno, João M. Repolho, Tiago Athanasiadis, Alekos Rosa, Rui Almeida-Val, Vera M. F. Coelho, Maria M. |
author2_role |
author author author author author author |
dc.contributor.none.fl_str_mv |
ARCA |
dc.contributor.author.fl_str_mv |
Jesus, Tiago F. Moreno, João M. Repolho, Tiago Athanasiadis, Alekos Rosa, Rui Almeida-Val, Vera M. F. Coelho, Maria M. |
dc.subject.por.fl_str_mv |
Gene expression Climate change Freshwater fish Energy metabolism Heat shock response Protein folding Circadian rhythms Protein structure prediction |
topic |
Gene expression Climate change Freshwater fish Energy metabolism Heat shock response Protein folding Circadian rhythms Protein structure prediction |
description |
This deposit is composed by the main article plus the supplementary materials of the publication. |
publishDate |
2017 |
dc.date.none.fl_str_mv |
2017-07-25T16:39:56Z 2017-07-18 2017-07-18T00:00:00Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10400.7/779 |
url |
http://hdl.handle.net/10400.7/779 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Jesus TF, Moreno JM, Repolho T, Athanasiadis A, Rosa R, Almeida-Val VMF, et al. (2017) Protein analysis and gene expression indicate differential vulnerability of Iberian fish species under a climate change scenario. PLoS ONE 12(7): e0181325. https://doi.org/10.1371/journal.pone.0181325 10.1371/journal.pone.0181325 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf application/vnd.openxmlformats-officedocument.wordprocessingml.document application/pdf application/vnd.openxmlformats-officedocument.wordprocessingml.document application/pdf application/vnd.openxmlformats-officedocument.wordprocessingml.document application/vnd.openxmlformats-officedocument.spreadsheetml.sheet application/vnd.openxmlformats-officedocument.wordprocessingml.document |
dc.publisher.none.fl_str_mv |
Public Library of Science |
publisher.none.fl_str_mv |
Public Library of Science |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
instname_str |
Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
instacron_str |
RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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1799130575686074368 |