International Efforts and Next Steps to Advance COVID-19 Vaccines Research and Production in Low- and Middle-Income Countries

Detalhes bibliográficos
Autor(a) principal: Du, Li
Data de Publicação: 2021
Outros Autores: Wang, Meng, Raposo, Vera Lúcia
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10316/97074
https://doi.org/10.3390/vaccines10010042
Resumo: Equitable and efficient distribution of COVID-19 vaccines continues to be a key issue in global health, and a targeted approach is needed to meet the World Health Organization’s world vaccination targets. Although some low-and middle-income countries (LMICs) are developing their own vaccines to address the distribution problem, legal and technical challenges have had a negative impact on productivity. This article explores relevant international legal instruments that can enable faster research and development of COVID-19 vaccines in LMICs, focusing on the role of biosafety standards, biological materials transfer, and key knowledge sharing. Our analysis has established that the potential of existing global health legal instruments has yet to be realized in order to close the productivity gap in LMICs and strengthen their vaccine manufacturing capacity. Additionally, mutual recognition of vaccine efficacy has become a new challenge for achieving global vaccination targets. We argue that the World Health Organization should continue its leading position by developing a more practical and targeted framework to help LMICs overcome challenges arising from technology transfer, knowledge sharing, and politics. © 2021 by the authors. Licensee MDPI, Basel, Switzerland.
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spelling International Efforts and Next Steps to Advance COVID-19 Vaccines Research and Production in Low- and Middle-Income CountriesCOVID-19 vaccinesGlobal health lawGlobal vaccine certificateLMICsVaccine distributionVaccine equityEquitable and efficient distribution of COVID-19 vaccines continues to be a key issue in global health, and a targeted approach is needed to meet the World Health Organization’s world vaccination targets. Although some low-and middle-income countries (LMICs) are developing their own vaccines to address the distribution problem, legal and technical challenges have had a negative impact on productivity. This article explores relevant international legal instruments that can enable faster research and development of COVID-19 vaccines in LMICs, focusing on the role of biosafety standards, biological materials transfer, and key knowledge sharing. Our analysis has established that the potential of existing global health legal instruments has yet to be realized in order to close the productivity gap in LMICs and strengthen their vaccine manufacturing capacity. Additionally, mutual recognition of vaccine efficacy has become a new challenge for achieving global vaccination targets. We argue that the World Health Organization should continue its leading position by developing a more practical and targeted framework to help LMICs overcome challenges arising from technology transfer, knowledge sharing, and politics. © 2021 by the authors. Licensee MDPI, Basel, Switzerland.Funding: This research was funded by the University of Macau, grant number MYRG2018-00074-FLL, and the Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences under the research grant Legal Issues Associated with Synthetic Biology Research and Development (Biosafety Issues), grant number CP-030-2021.2021info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttp://hdl.handle.net/10316/97074http://hdl.handle.net/10316/97074https://doi.org/10.3390/vaccines10010042eng2076-393XDu, LiWang, MengRaposo, Vera Lúciainfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2022-05-25T06:57:18Zoai:estudogeral.uc.pt:10316/97074Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T21:15:12.029873Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv International Efforts and Next Steps to Advance COVID-19 Vaccines Research and Production in Low- and Middle-Income Countries
title International Efforts and Next Steps to Advance COVID-19 Vaccines Research and Production in Low- and Middle-Income Countries
spellingShingle International Efforts and Next Steps to Advance COVID-19 Vaccines Research and Production in Low- and Middle-Income Countries
Du, Li
COVID-19 vaccines
Global health law
Global vaccine certificate
LMICs
Vaccine distribution
Vaccine equity
title_short International Efforts and Next Steps to Advance COVID-19 Vaccines Research and Production in Low- and Middle-Income Countries
title_full International Efforts and Next Steps to Advance COVID-19 Vaccines Research and Production in Low- and Middle-Income Countries
title_fullStr International Efforts and Next Steps to Advance COVID-19 Vaccines Research and Production in Low- and Middle-Income Countries
title_full_unstemmed International Efforts and Next Steps to Advance COVID-19 Vaccines Research and Production in Low- and Middle-Income Countries
title_sort International Efforts and Next Steps to Advance COVID-19 Vaccines Research and Production in Low- and Middle-Income Countries
author Du, Li
author_facet Du, Li
Wang, Meng
Raposo, Vera Lúcia
author_role author
author2 Wang, Meng
Raposo, Vera Lúcia
author2_role author
author
dc.contributor.author.fl_str_mv Du, Li
Wang, Meng
Raposo, Vera Lúcia
dc.subject.por.fl_str_mv COVID-19 vaccines
Global health law
Global vaccine certificate
LMICs
Vaccine distribution
Vaccine equity
topic COVID-19 vaccines
Global health law
Global vaccine certificate
LMICs
Vaccine distribution
Vaccine equity
description Equitable and efficient distribution of COVID-19 vaccines continues to be a key issue in global health, and a targeted approach is needed to meet the World Health Organization’s world vaccination targets. Although some low-and middle-income countries (LMICs) are developing their own vaccines to address the distribution problem, legal and technical challenges have had a negative impact on productivity. This article explores relevant international legal instruments that can enable faster research and development of COVID-19 vaccines in LMICs, focusing on the role of biosafety standards, biological materials transfer, and key knowledge sharing. Our analysis has established that the potential of existing global health legal instruments has yet to be realized in order to close the productivity gap in LMICs and strengthen their vaccine manufacturing capacity. Additionally, mutual recognition of vaccine efficacy has become a new challenge for achieving global vaccination targets. We argue that the World Health Organization should continue its leading position by developing a more practical and targeted framework to help LMICs overcome challenges arising from technology transfer, knowledge sharing, and politics. © 2021 by the authors. Licensee MDPI, Basel, Switzerland.
publishDate 2021
dc.date.none.fl_str_mv 2021
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dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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dc.identifier.uri.fl_str_mv http://hdl.handle.net/10316/97074
http://hdl.handle.net/10316/97074
https://doi.org/10.3390/vaccines10010042
url http://hdl.handle.net/10316/97074
https://doi.org/10.3390/vaccines10010042
dc.language.iso.fl_str_mv eng
language eng
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