Drug release assays from new chitosan/pHEMA membranes obtained by gamma irradiation

Detalhes bibliográficos
Autor(a) principal: Casimiro, M. H.
Data de Publicação: 2007
Outros Autores: Gil, M. H., Leal, J. P.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10316/3781
https://doi.org/10.1016/j.nimb.2007.09.013
Resumo: With the purpose of obtaining a biocompatible and microbiologically safe matrix that simultaneously could be used as wound dressing material and as a controlled drug release system, membranes with different thickness and different contents in chitosan and hydroxyethyl methacrylate (HEMA) have been prepared by [gamma] irradiation from a 60Co source. Antibiotic release experiments were performed before or after irradiation over amoxicillin loaded chitosan/pHEMA membranes in physiological saline solution, and monitored by UV-Vis spectrometry.
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spelling Drug release assays from new chitosan/pHEMA membranes obtained by gamma irradiationDrug releaseGamma radiation, chitosanMembranesAmoxicillinWith the purpose of obtaining a biocompatible and microbiologically safe matrix that simultaneously could be used as wound dressing material and as a controlled drug release system, membranes with different thickness and different contents in chitosan and hydroxyethyl methacrylate (HEMA) have been prepared by [gamma] irradiation from a 60Co source. Antibiotic release experiments were performed before or after irradiation over amoxicillin loaded chitosan/pHEMA membranes in physiological saline solution, and monitored by UV-Vis spectrometry.http://www.sciencedirect.com/science/article/B6TJN-4PMJJX9-9/1/0b03eba841e57ba5c341c5bf1539b62c2007info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleaplication/PDFhttp://hdl.handle.net/10316/3781http://hdl.handle.net/10316/3781https://doi.org/10.1016/j.nimb.2007.09.013engNuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms. 265:1 (2007) 406-409Casimiro, M. H.Gil, M. H.Leal, J. P.info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2020-11-06T16:49:24Zoai:estudogeral.uc.pt:10316/3781Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T20:59:19.859201Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Drug release assays from new chitosan/pHEMA membranes obtained by gamma irradiation
title Drug release assays from new chitosan/pHEMA membranes obtained by gamma irradiation
spellingShingle Drug release assays from new chitosan/pHEMA membranes obtained by gamma irradiation
Casimiro, M. H.
Drug release
Gamma radiation, chitosan
Membranes
Amoxicillin
title_short Drug release assays from new chitosan/pHEMA membranes obtained by gamma irradiation
title_full Drug release assays from new chitosan/pHEMA membranes obtained by gamma irradiation
title_fullStr Drug release assays from new chitosan/pHEMA membranes obtained by gamma irradiation
title_full_unstemmed Drug release assays from new chitosan/pHEMA membranes obtained by gamma irradiation
title_sort Drug release assays from new chitosan/pHEMA membranes obtained by gamma irradiation
author Casimiro, M. H.
author_facet Casimiro, M. H.
Gil, M. H.
Leal, J. P.
author_role author
author2 Gil, M. H.
Leal, J. P.
author2_role author
author
dc.contributor.author.fl_str_mv Casimiro, M. H.
Gil, M. H.
Leal, J. P.
dc.subject.por.fl_str_mv Drug release
Gamma radiation, chitosan
Membranes
Amoxicillin
topic Drug release
Gamma radiation, chitosan
Membranes
Amoxicillin
description With the purpose of obtaining a biocompatible and microbiologically safe matrix that simultaneously could be used as wound dressing material and as a controlled drug release system, membranes with different thickness and different contents in chitosan and hydroxyethyl methacrylate (HEMA) have been prepared by [gamma] irradiation from a 60Co source. Antibiotic release experiments were performed before or after irradiation over amoxicillin loaded chitosan/pHEMA membranes in physiological saline solution, and monitored by UV-Vis spectrometry.
publishDate 2007
dc.date.none.fl_str_mv 2007
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10316/3781
http://hdl.handle.net/10316/3781
https://doi.org/10.1016/j.nimb.2007.09.013
url http://hdl.handle.net/10316/3781
https://doi.org/10.1016/j.nimb.2007.09.013
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms. 265:1 (2007) 406-409
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
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