Morphological Changes of the Internal Carotid Artery: Prevalence and Characteristics. A Clinical and Ultrasonographic Study in a Series of 19 804 Patients Over 25 Years Old
Autor(a) principal: | |
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Data de Publicação: | 2018 |
Outros Autores: | , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10400.17/4428 |
Resumo: | Background and purpose: Morphological changes of the internal carotid arteries (McICA) are frequently found during cervical ultrasound studies. However, the etiology of McICA remains controversial. During this study, the prevalence and demographic characteristics of McICA, such as kinking, coiling or looping identified by Doppler ultrasound, were analysed and its relationship with vascular risk factors and stroke was assessed. Methods: A retrospective study was performed by analysing 19 804 patients who were subjected to cervical ultrasonographic study between January 2000 and June 2012. The data were statistically analysed with SPSS® 20 and a multivariate logistic regression was performed. Statistical significance was accepted for P < 0.05 and 95% confidence intervals (CIs) were used. Results: Morphological changes of the internal carotid arteries were present in 2678 patients (13.5%) and were unilateral in 61.6% of these cases. Carotid kinking was found in 80% of the patients, coiling in 16% and looping in 1%. In multivariate analysis, the presence of McICA was related to older groups (1.04; 95% CI, 1.04-1.05; P < 0.01), female gender (1.78; 95% CI, 1.64-1.94; P < 0.01), patients with hyperlipidemia (1.28; 95% CI, 1.17-1.40; P < 0.01), carotid thickness (1.22; 95% CI, 1.13-1.33; P < 0.01) and cardiac or cardioembolic disease (1.11; 95% CI, 1.01-1.21; P = 0.02). The results of this study indicate that kinking in the carotid artery was associated with ipsilateral cerebral ischemic events (1.43; 95% CI, 1.040-1.958; P < 0.05). Conclusion: Morphological changes of the internal carotid arteries were associated with aging, female gender and patients with hyperlipidemia, hypertension, diabetes and heart disease. Kinking was associated with ipsilateral cerebral ischemia. |
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Morphological Changes of the Internal Carotid Artery: Prevalence and Characteristics. A Clinical and Ultrasonographic Study in a Series of 19 804 Patients Over 25 Years OldHSJ MEDAdultAgedAged, 80 and overAgingFemaleMaleHumansMiddle AgedBrain Ischemia / diagnostic imagingCarotid Artery, Internal / anatomy & histologyCarotid Artery, Internal / diagnostic imaging*Carotid Artery, Internal / growth & development*Carotid Intima-Media ThicknessDiabetes Complications / epidemiologyHeart Diseases / epidemiologyHyperlipidemias / complicationsHypertension / complicationsImage Processing, Computer-AssistedPrevalenceRetrospective StudiesSex CharacteristicsUltrasonographyBackground and purpose: Morphological changes of the internal carotid arteries (McICA) are frequently found during cervical ultrasound studies. However, the etiology of McICA remains controversial. During this study, the prevalence and demographic characteristics of McICA, such as kinking, coiling or looping identified by Doppler ultrasound, were analysed and its relationship with vascular risk factors and stroke was assessed. Methods: A retrospective study was performed by analysing 19 804 patients who were subjected to cervical ultrasonographic study between January 2000 and June 2012. The data were statistically analysed with SPSS® 20 and a multivariate logistic regression was performed. Statistical significance was accepted for P < 0.05 and 95% confidence intervals (CIs) were used. Results: Morphological changes of the internal carotid arteries were present in 2678 patients (13.5%) and were unilateral in 61.6% of these cases. Carotid kinking was found in 80% of the patients, coiling in 16% and looping in 1%. In multivariate analysis, the presence of McICA was related to older groups (1.04; 95% CI, 1.04-1.05; P < 0.01), female gender (1.78; 95% CI, 1.64-1.94; P < 0.01), patients with hyperlipidemia (1.28; 95% CI, 1.17-1.40; P < 0.01), carotid thickness (1.22; 95% CI, 1.13-1.33; P < 0.01) and cardiac or cardioembolic disease (1.11; 95% CI, 1.01-1.21; P = 0.02). The results of this study indicate that kinking in the carotid artery was associated with ipsilateral cerebral ischemic events (1.43; 95% CI, 1.040-1.958; P < 0.05). Conclusion: Morphological changes of the internal carotid arteries were associated with aging, female gender and patients with hyperlipidemia, hypertension, diabetes and heart disease. Kinking was associated with ipsilateral cerebral ischemia.WileyRepositório do Centro Hospitalar Universitário de Lisboa Central, EPEMartins, HMayer, ABatista, PSoares, FAlmeida, VPedro, AJOliveira, V2023-03-01T12:23:18Z20182018-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.17/4428engEur J Neurol . 2018 Jan;25(1):171-177.10.1111/ene.13491.info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-03-10T09:46:24Zoai:repositorio.chlc.min-saude.pt:10400.17/4428Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T17:21:46.917547Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Morphological Changes of the Internal Carotid Artery: Prevalence and Characteristics. A Clinical and Ultrasonographic Study in a Series of 19 804 Patients Over 25 Years Old |
title |
Morphological Changes of the Internal Carotid Artery: Prevalence and Characteristics. A Clinical and Ultrasonographic Study in a Series of 19 804 Patients Over 25 Years Old |
spellingShingle |
Morphological Changes of the Internal Carotid Artery: Prevalence and Characteristics. A Clinical and Ultrasonographic Study in a Series of 19 804 Patients Over 25 Years Old Martins, H HSJ MED Adult Aged Aged, 80 and over Aging Female Male Humans Middle Aged Brain Ischemia / diagnostic imaging Carotid Artery, Internal / anatomy & histology Carotid Artery, Internal / diagnostic imaging* Carotid Artery, Internal / growth & development* Carotid Intima-Media Thickness Diabetes Complications / epidemiology Heart Diseases / epidemiology Hyperlipidemias / complications Hypertension / complications Image Processing, Computer-Assisted Prevalence Retrospective Studies Sex Characteristics Ultrasonography |
title_short |
Morphological Changes of the Internal Carotid Artery: Prevalence and Characteristics. A Clinical and Ultrasonographic Study in a Series of 19 804 Patients Over 25 Years Old |
title_full |
Morphological Changes of the Internal Carotid Artery: Prevalence and Characteristics. A Clinical and Ultrasonographic Study in a Series of 19 804 Patients Over 25 Years Old |
title_fullStr |
Morphological Changes of the Internal Carotid Artery: Prevalence and Characteristics. A Clinical and Ultrasonographic Study in a Series of 19 804 Patients Over 25 Years Old |
title_full_unstemmed |
Morphological Changes of the Internal Carotid Artery: Prevalence and Characteristics. A Clinical and Ultrasonographic Study in a Series of 19 804 Patients Over 25 Years Old |
title_sort |
Morphological Changes of the Internal Carotid Artery: Prevalence and Characteristics. A Clinical and Ultrasonographic Study in a Series of 19 804 Patients Over 25 Years Old |
author |
Martins, H |
author_facet |
Martins, H Mayer, A Batista, P Soares, F Almeida, V Pedro, AJ Oliveira, V |
author_role |
author |
author2 |
Mayer, A Batista, P Soares, F Almeida, V Pedro, AJ Oliveira, V |
author2_role |
author author author author author author |
dc.contributor.none.fl_str_mv |
Repositório do Centro Hospitalar Universitário de Lisboa Central, EPE |
dc.contributor.author.fl_str_mv |
Martins, H Mayer, A Batista, P Soares, F Almeida, V Pedro, AJ Oliveira, V |
dc.subject.por.fl_str_mv |
HSJ MED Adult Aged Aged, 80 and over Aging Female Male Humans Middle Aged Brain Ischemia / diagnostic imaging Carotid Artery, Internal / anatomy & histology Carotid Artery, Internal / diagnostic imaging* Carotid Artery, Internal / growth & development* Carotid Intima-Media Thickness Diabetes Complications / epidemiology Heart Diseases / epidemiology Hyperlipidemias / complications Hypertension / complications Image Processing, Computer-Assisted Prevalence Retrospective Studies Sex Characteristics Ultrasonography |
topic |
HSJ MED Adult Aged Aged, 80 and over Aging Female Male Humans Middle Aged Brain Ischemia / diagnostic imaging Carotid Artery, Internal / anatomy & histology Carotid Artery, Internal / diagnostic imaging* Carotid Artery, Internal / growth & development* Carotid Intima-Media Thickness Diabetes Complications / epidemiology Heart Diseases / epidemiology Hyperlipidemias / complications Hypertension / complications Image Processing, Computer-Assisted Prevalence Retrospective Studies Sex Characteristics Ultrasonography |
description |
Background and purpose: Morphological changes of the internal carotid arteries (McICA) are frequently found during cervical ultrasound studies. However, the etiology of McICA remains controversial. During this study, the prevalence and demographic characteristics of McICA, such as kinking, coiling or looping identified by Doppler ultrasound, were analysed and its relationship with vascular risk factors and stroke was assessed. Methods: A retrospective study was performed by analysing 19 804 patients who were subjected to cervical ultrasonographic study between January 2000 and June 2012. The data were statistically analysed with SPSS® 20 and a multivariate logistic regression was performed. Statistical significance was accepted for P < 0.05 and 95% confidence intervals (CIs) were used. Results: Morphological changes of the internal carotid arteries were present in 2678 patients (13.5%) and were unilateral in 61.6% of these cases. Carotid kinking was found in 80% of the patients, coiling in 16% and looping in 1%. In multivariate analysis, the presence of McICA was related to older groups (1.04; 95% CI, 1.04-1.05; P < 0.01), female gender (1.78; 95% CI, 1.64-1.94; P < 0.01), patients with hyperlipidemia (1.28; 95% CI, 1.17-1.40; P < 0.01), carotid thickness (1.22; 95% CI, 1.13-1.33; P < 0.01) and cardiac or cardioembolic disease (1.11; 95% CI, 1.01-1.21; P = 0.02). The results of this study indicate that kinking in the carotid artery was associated with ipsilateral cerebral ischemic events (1.43; 95% CI, 1.040-1.958; P < 0.05). Conclusion: Morphological changes of the internal carotid arteries were associated with aging, female gender and patients with hyperlipidemia, hypertension, diabetes and heart disease. Kinking was associated with ipsilateral cerebral ischemia. |
publishDate |
2018 |
dc.date.none.fl_str_mv |
2018 2018-01-01T00:00:00Z 2023-03-01T12:23:18Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10400.17/4428 |
url |
http://hdl.handle.net/10400.17/4428 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Eur J Neurol . 2018 Jan;25(1):171-177. 10.1111/ene.13491. |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Wiley |
publisher.none.fl_str_mv |
Wiley |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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1799131312838148096 |