Endotoxin as a Marker for Water Quality

Detalhes bibliográficos
Autor(a) principal: Sattar, Anas A.
Data de Publicação: 2022
Outros Autores: Good, Christian R., Saletes, Margaux, Brandão, João, Jackson, Simon K.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10400.18/8521
Resumo: This article belongs to the Special Issue Environmental Microbiology: Perspectives for Medicine and Public Health.
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spelling Endotoxin as a Marker for Water QualityBacterisKEndotoxinFaecal ContaminationLAL AssayWatert TestingDrinking WaterAgentes Microbianos e AmbienteThis article belongs to the Special Issue Environmental Microbiology: Perspectives for Medicine and Public Health.Background: Water quality testing is vital to protect human health. Current testing relies mainly on culture-based detection of faecal indicator organisms such as Escherichia coli (E.coli). However, bacterial cultures are a slow process, taking 24-48 h and requiring specialised laboratories and trained personnel. Access to such laboratories is often sparse in developing countries and there are many fatalities deriving from poor water quality. Endotoxin is a molecular component of Gram-negative bacterial cell walls and can be used to detect their presence in drinking water. Method: The current study used a novel assay (BacterisK) to rapidly detect endotoxin in various water samples and correlate the results with E. coli content measured by culture methods. The data generated by the BacterisK assay are presented as an 'endotoxin risk' (ER). Results: The ER values correlate with E. coli and thus endotoxin can be used as a marker of faecal contamination in water. Moreover, the BacterisK assay provides data in near real-time and can be used in situ allowing water quality testing at different spatial and temporal locations. Conclusion: We suggest that BacterisK can be used as a convenient risk assessment tool to assess water quality where results are required quickly or access to laboratories is lacking.MDPIRepositório Científico do Instituto Nacional de SaúdeSattar, Anas A.Good, Christian R.Saletes, MargauxBrandão, JoãoJackson, Simon K.2023-02-09T14:30:53Z2022-12-092022-12-09T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.18/8521engInt J Environ Res Public Health. 2022 Dec 9;19(24):16528. doi: 10.3390/ijerph192416528.1660-460110.3390/ijerph192416528info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-07-20T15:42:35Zoai:repositorio.insa.pt:10400.18/8521Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T18:43:05.582951Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Endotoxin as a Marker for Water Quality
title Endotoxin as a Marker for Water Quality
spellingShingle Endotoxin as a Marker for Water Quality
Sattar, Anas A.
BacterisK
Endotoxin
Faecal Contamination
LAL Assay
Watert Testing
Drinking Water
Agentes Microbianos e Ambiente
title_short Endotoxin as a Marker for Water Quality
title_full Endotoxin as a Marker for Water Quality
title_fullStr Endotoxin as a Marker for Water Quality
title_full_unstemmed Endotoxin as a Marker for Water Quality
title_sort Endotoxin as a Marker for Water Quality
author Sattar, Anas A.
author_facet Sattar, Anas A.
Good, Christian R.
Saletes, Margaux
Brandão, João
Jackson, Simon K.
author_role author
author2 Good, Christian R.
Saletes, Margaux
Brandão, João
Jackson, Simon K.
author2_role author
author
author
author
dc.contributor.none.fl_str_mv Repositório Científico do Instituto Nacional de Saúde
dc.contributor.author.fl_str_mv Sattar, Anas A.
Good, Christian R.
Saletes, Margaux
Brandão, João
Jackson, Simon K.
dc.subject.por.fl_str_mv BacterisK
Endotoxin
Faecal Contamination
LAL Assay
Watert Testing
Drinking Water
Agentes Microbianos e Ambiente
topic BacterisK
Endotoxin
Faecal Contamination
LAL Assay
Watert Testing
Drinking Water
Agentes Microbianos e Ambiente
description This article belongs to the Special Issue Environmental Microbiology: Perspectives for Medicine and Public Health.
publishDate 2022
dc.date.none.fl_str_mv 2022-12-09
2022-12-09T00:00:00Z
2023-02-09T14:30:53Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10400.18/8521
url http://hdl.handle.net/10400.18/8521
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Int J Environ Res Public Health. 2022 Dec 9;19(24):16528. doi: 10.3390/ijerph192416528.
1660-4601
10.3390/ijerph192416528
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv MDPI
publisher.none.fl_str_mv MDPI
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
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reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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