Development of an empirical correlation for Newtonian and non-Newtonian fluids in a stirred tank reactor, to predict oxygen mass transfer rates

Detalhes bibliográficos
Autor(a) principal: Raposo, Sara
Data de Publicação: 2010
Outros Autores: Azevedo, F., Lima-Costa, Maria Emília
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10400.1/4792
Resumo: Most of animal and plant cell cultures present a non-Newtonian behaviour that has a deep effect on the technological performance of bioreactors, affecting the pattern of mixing, the power input required and on the mass and energy transfer as well. In aerobic cultures, the oxygen mass transfer is still a bottleneck, particularly at industrial scale-up, where the high-cell-density biomass and production of metabolites provoke the increase on the viscosity culture, lowering the production yield and eventually losing economical process viability.
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spelling Development of an empirical correlation for Newtonian and non-Newtonian fluids in a stirred tank reactor, to predict oxygen mass transfer ratesOxygen transferEmpirical correlationNon-Newtonian fluidsStirred tank reactorMost of animal and plant cell cultures present a non-Newtonian behaviour that has a deep effect on the technological performance of bioreactors, affecting the pattern of mixing, the power input required and on the mass and energy transfer as well. In aerobic cultures, the oxygen mass transfer is still a bottleneck, particularly at industrial scale-up, where the high-cell-density biomass and production of metabolites provoke the increase on the viscosity culture, lowering the production yield and eventually losing economical process viability.ElsevierSapientiaRaposo, SaraAzevedo, F.Lima-Costa, Maria Emília2014-07-22T12:11:06Z20102014-07-22T11:42:09Z2010-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.1/4792engRaposo, S.; Azevedo, F.; Lima-Costa, M. E.Development of an empirical correlation for Newtonian and non-Newtonian fluids in a stirred tank reactor, to predict oxygen mass transfer rates, Journal of Biotechnology, 150, --, S395-S3, 2010.0168-1656AUT: SRA01180;10.1016/j.jbiotec.2010.09.509info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-07-24T10:16:00Zoai:sapientia.ualg.pt:10400.1/4792Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T19:58:03.397968Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Development of an empirical correlation for Newtonian and non-Newtonian fluids in a stirred tank reactor, to predict oxygen mass transfer rates
title Development of an empirical correlation for Newtonian and non-Newtonian fluids in a stirred tank reactor, to predict oxygen mass transfer rates
spellingShingle Development of an empirical correlation for Newtonian and non-Newtonian fluids in a stirred tank reactor, to predict oxygen mass transfer rates
Raposo, Sara
Oxygen transfer
Empirical correlation
Non-Newtonian fluids
Stirred tank reactor
title_short Development of an empirical correlation for Newtonian and non-Newtonian fluids in a stirred tank reactor, to predict oxygen mass transfer rates
title_full Development of an empirical correlation for Newtonian and non-Newtonian fluids in a stirred tank reactor, to predict oxygen mass transfer rates
title_fullStr Development of an empirical correlation for Newtonian and non-Newtonian fluids in a stirred tank reactor, to predict oxygen mass transfer rates
title_full_unstemmed Development of an empirical correlation for Newtonian and non-Newtonian fluids in a stirred tank reactor, to predict oxygen mass transfer rates
title_sort Development of an empirical correlation for Newtonian and non-Newtonian fluids in a stirred tank reactor, to predict oxygen mass transfer rates
author Raposo, Sara
author_facet Raposo, Sara
Azevedo, F.
Lima-Costa, Maria Emília
author_role author
author2 Azevedo, F.
Lima-Costa, Maria Emília
author2_role author
author
dc.contributor.none.fl_str_mv Sapientia
dc.contributor.author.fl_str_mv Raposo, Sara
Azevedo, F.
Lima-Costa, Maria Emília
dc.subject.por.fl_str_mv Oxygen transfer
Empirical correlation
Non-Newtonian fluids
Stirred tank reactor
topic Oxygen transfer
Empirical correlation
Non-Newtonian fluids
Stirred tank reactor
description Most of animal and plant cell cultures present a non-Newtonian behaviour that has a deep effect on the technological performance of bioreactors, affecting the pattern of mixing, the power input required and on the mass and energy transfer as well. In aerobic cultures, the oxygen mass transfer is still a bottleneck, particularly at industrial scale-up, where the high-cell-density biomass and production of metabolites provoke the increase on the viscosity culture, lowering the production yield and eventually losing economical process viability.
publishDate 2010
dc.date.none.fl_str_mv 2010
2010-01-01T00:00:00Z
2014-07-22T12:11:06Z
2014-07-22T11:42:09Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10400.1/4792
url http://hdl.handle.net/10400.1/4792
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Raposo, S.; Azevedo, F.; Lima-Costa, M. E.Development of an empirical correlation for Newtonian and non-Newtonian fluids in a stirred tank reactor, to predict oxygen mass transfer rates, Journal of Biotechnology, 150, --, S395-S3, 2010.
0168-1656
AUT: SRA01180;
10.1016/j.jbiotec.2010.09.509
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
repository.mail.fl_str_mv
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