Congenital Heart Disease Prevalence in Portugal in 2015: Data from the National Register of Congenital Anomalies
Autor(a) principal: | |
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Data de Publicação: | 2020 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | por eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/12111 |
Resumo: | Introduction: The prevalence at birth of congenital heart disease in Portugal is 8.3/1000 births; undetected critical congenital heart disease may result in adverse outcomes for the fetus/newborn infant. This study describes the reported cases of congenital heart disease in Portugal in 2015 regarding antenatal diagnosis, cardiac defect, and presence of other congenital anomalies/chromosomal abnormalities. These indicators are compared in live births and medical pregnancy terminations. Additionally, postnatal deaths were characterized.Material and Methods: Congenital heart disease data derived from the 2015 Portuguese National Registry of Congenital Birth Defects were analyzed. The prevalence rates per 1000 births were assessed by the chi-square test of independence.Results: The prevalence of congenital heart disease in this study was 5/1000 live-births (339 live-births, 20% with critical defects). The most common defects were ventricular septal defect (38%), atrial septal defect (15%), aortic coarctation (7%), tetralogy of Fallot (7%) and pulmonary stenosis (5%). One third of the live births had antenatal diagnosis of congenital heart disease. In the live-births with critical congenital heart disease, 54% had antenatal diagnosis and 14% were diagnosed at birth. There were records of 84 pregnancy terminations; 49% had critical defects, 75% had non-cardiac congenital anomalies and 40% had chromosomal abnormalities. There were 15 postnatal deaths recorded (3.4% mortality rate), associated with prematurity/low birthweight, critical congenital heart disease, other non-cardiac congenital anomalies and chromosomal abnormalities.Discussion: The data analysis revealed a prevalence of congenital heart disease in this study of 5/1000 births (inferior to other international studies), with a distribution per type of anomaly similar to that reported in previously published work. There were significant regional differences that need further studying.Conclusion: These results are paramount to characterize the Portuguese scenario and improve Healthcare planning. It is important to improve reporting in the Portuguese National Registry of Congenital Birth Defects. |
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Congenital Heart Disease Prevalence in Portugal in 2015: Data from the National Register of Congenital AnomaliesPrevalência de Cardiopatias Congénitas em Portugal em 2015: Dados do Registo Nacional de Anomalias CongénitasHeart DefectsCongenital / epidemiologyPortugalRegistriesCardiopatias Congénitas/epidemiologiaPortugalRegistosIntroduction: The prevalence at birth of congenital heart disease in Portugal is 8.3/1000 births; undetected critical congenital heart disease may result in adverse outcomes for the fetus/newborn infant. This study describes the reported cases of congenital heart disease in Portugal in 2015 regarding antenatal diagnosis, cardiac defect, and presence of other congenital anomalies/chromosomal abnormalities. These indicators are compared in live births and medical pregnancy terminations. Additionally, postnatal deaths were characterized.Material and Methods: Congenital heart disease data derived from the 2015 Portuguese National Registry of Congenital Birth Defects were analyzed. The prevalence rates per 1000 births were assessed by the chi-square test of independence.Results: The prevalence of congenital heart disease in this study was 5/1000 live-births (339 live-births, 20% with critical defects). The most common defects were ventricular septal defect (38%), atrial septal defect (15%), aortic coarctation (7%), tetralogy of Fallot (7%) and pulmonary stenosis (5%). One third of the live births had antenatal diagnosis of congenital heart disease. In the live-births with critical congenital heart disease, 54% had antenatal diagnosis and 14% were diagnosed at birth. There were records of 84 pregnancy terminations; 49% had critical defects, 75% had non-cardiac congenital anomalies and 40% had chromosomal abnormalities. There were 15 postnatal deaths recorded (3.4% mortality rate), associated with prematurity/low birthweight, critical congenital heart disease, other non-cardiac congenital anomalies and chromosomal abnormalities.Discussion: The data analysis revealed a prevalence of congenital heart disease in this study of 5/1000 births (inferior to other international studies), with a distribution per type of anomaly similar to that reported in previously published work. There were significant regional differences that need further studying.Conclusion: These results are paramount to characterize the Portuguese scenario and improve Healthcare planning. It is important to improve reporting in the Portuguese National Registry of Congenital Birth Defects.Introdução: A prevalência de cardiopatias congénitas em Portugal é de 8,3/1000 nascimentos; cardiopatias congénitas críticas não detectadas podem resultar em graves consequências para o feto/recém-nascido. O objectivo deste trabalho é descrever os casos de cardiopatia congénita reportados em Portugal em 2015 quanto ao diagnóstico pré-natal, patologia cardíaca e à presença de outras malformações congénitas ou anomalias cromossómicas. Estas características são comparadas nos subgrupos dos nados-vivos e de interrupção médica da gravidez. Por último, caracterizam-se os óbitos.Material e Métodos: Os dados de cardiopatias congénitas reportadas ao Registo Nacional de Anomalias Congénitas em 2015 foram analisados, e calculadas as taxas de prevalência por 1000 nascimentos, comparadas utilizando teste de independência do quiquadrado.Resultados: A prevalência de cardiopatias congénitas neste estudo foi de 5/1000, (339 nados-vivos, 20% com cardiopatias congénitas críticas). As cardiopatias mais frequentes foram as seguintes: comunicação interventricular (38%), comunicação interauricular (15%), coartação da aorta (7%), tetralogia de Fallot (7%) e estenose pulmonar (5%). Um terço dos nados-vivos teve diagnostico pré-natal de cardiopatia. Dos nados-vivos com cardiopatias congénitas críticas, 54% teve diagnostico pré-natal e 14% foi diagnosticado ao nascer. Foram identificados 84 registos de interrupção médica da gravidez; 49% apresentava cardiopatias congénitas críticas, 75% outras malformações associadas, e 40% cromossomopatias. Foram registados 15 óbitos (3,4% de mortalidade) associados a prematuridade e/ou baixo-peso ao nascer, cardiopatias congénitas críticas, outras malformações e anomalias cromossómicas.Discussão: A prevalência de cardiopatias congénitas neste estudo (5/1000 nascimentos) foi inferior ao descrito noutros estudos internacionais, não obstante uma distribuição por tipo de anomalia semelhante ao previamente reportado. Observaram-se assimetrias regionais significativas que necessitam de mais investigação.Conclusão: Este estudo é relevante para melhor conhecimento da realidade nacional e organização dos Cuidados de Saúde. É importante uma maior adesão ao Registo Nacional de Anomalias Congénitas.Ordem dos Médicos2020-07-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfapplication/pdfapplication/pdfapplication/mswordapplication/vnd.openxmlformats-officedocument.wordprocessingml.documentapplication/pdfhttps://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/12111oai:ojs.www.actamedicaportuguesa.com:article/12111Acta Médica Portuguesa; Vol. 33 No. 7-8 (2020): July-August; 491-499Acta Médica Portuguesa; Vol. 33 N.º 7-8 (2020): Julho-Agosto; 491-4991646-07580870-399Xreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAPporenghttps://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/12111https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/12111/6006https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/12111/6707https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/12111/11593https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/12111/11932https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/12111/12003https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/12111/12060Direitos de Autor (c) 2020 Acta Médica Portuguesainfo:eu-repo/semantics/openAccessMelo, Isabel Saraiva deBraz, PaulaRoquette, RitaSousa, PauloNunes, CarlaDias, Carlos2022-12-20T11:06:31Zoai:ojs.www.actamedicaportuguesa.com:article/12111Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T16:20:08.511613Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Congenital Heart Disease Prevalence in Portugal in 2015: Data from the National Register of Congenital Anomalies Prevalência de Cardiopatias Congénitas em Portugal em 2015: Dados do Registo Nacional de Anomalias Congénitas |
title |
Congenital Heart Disease Prevalence in Portugal in 2015: Data from the National Register of Congenital Anomalies |
spellingShingle |
Congenital Heart Disease Prevalence in Portugal in 2015: Data from the National Register of Congenital Anomalies Melo, Isabel Saraiva de Heart Defects Congenital / epidemiology Portugal Registries Cardiopatias Congénitas/epidemiologia Portugal Registos |
title_short |
Congenital Heart Disease Prevalence in Portugal in 2015: Data from the National Register of Congenital Anomalies |
title_full |
Congenital Heart Disease Prevalence in Portugal in 2015: Data from the National Register of Congenital Anomalies |
title_fullStr |
Congenital Heart Disease Prevalence in Portugal in 2015: Data from the National Register of Congenital Anomalies |
title_full_unstemmed |
Congenital Heart Disease Prevalence in Portugal in 2015: Data from the National Register of Congenital Anomalies |
title_sort |
Congenital Heart Disease Prevalence in Portugal in 2015: Data from the National Register of Congenital Anomalies |
author |
Melo, Isabel Saraiva de |
author_facet |
Melo, Isabel Saraiva de Braz, Paula Roquette, Rita Sousa, Paulo Nunes, Carla Dias, Carlos |
author_role |
author |
author2 |
Braz, Paula Roquette, Rita Sousa, Paulo Nunes, Carla Dias, Carlos |
author2_role |
author author author author author |
dc.contributor.author.fl_str_mv |
Melo, Isabel Saraiva de Braz, Paula Roquette, Rita Sousa, Paulo Nunes, Carla Dias, Carlos |
dc.subject.por.fl_str_mv |
Heart Defects Congenital / epidemiology Portugal Registries Cardiopatias Congénitas/epidemiologia Portugal Registos |
topic |
Heart Defects Congenital / epidemiology Portugal Registries Cardiopatias Congénitas/epidemiologia Portugal Registos |
description |
Introduction: The prevalence at birth of congenital heart disease in Portugal is 8.3/1000 births; undetected critical congenital heart disease may result in adverse outcomes for the fetus/newborn infant. This study describes the reported cases of congenital heart disease in Portugal in 2015 regarding antenatal diagnosis, cardiac defect, and presence of other congenital anomalies/chromosomal abnormalities. These indicators are compared in live births and medical pregnancy terminations. Additionally, postnatal deaths were characterized.Material and Methods: Congenital heart disease data derived from the 2015 Portuguese National Registry of Congenital Birth Defects were analyzed. The prevalence rates per 1000 births were assessed by the chi-square test of independence.Results: The prevalence of congenital heart disease in this study was 5/1000 live-births (339 live-births, 20% with critical defects). The most common defects were ventricular septal defect (38%), atrial septal defect (15%), aortic coarctation (7%), tetralogy of Fallot (7%) and pulmonary stenosis (5%). One third of the live births had antenatal diagnosis of congenital heart disease. In the live-births with critical congenital heart disease, 54% had antenatal diagnosis and 14% were diagnosed at birth. There were records of 84 pregnancy terminations; 49% had critical defects, 75% had non-cardiac congenital anomalies and 40% had chromosomal abnormalities. There were 15 postnatal deaths recorded (3.4% mortality rate), associated with prematurity/low birthweight, critical congenital heart disease, other non-cardiac congenital anomalies and chromosomal abnormalities.Discussion: The data analysis revealed a prevalence of congenital heart disease in this study of 5/1000 births (inferior to other international studies), with a distribution per type of anomaly similar to that reported in previously published work. There were significant regional differences that need further studying.Conclusion: These results are paramount to characterize the Portuguese scenario and improve Healthcare planning. It is important to improve reporting in the Portuguese National Registry of Congenital Birth Defects. |
publishDate |
2020 |
dc.date.none.fl_str_mv |
2020-07-01 |
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info:eu-repo/semantics/publishedVersion |
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info:eu-repo/semantics/article |
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article |
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publishedVersion |
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https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/12111 oai:ojs.www.actamedicaportuguesa.com:article/12111 |
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https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/12111 |
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oai:ojs.www.actamedicaportuguesa.com:article/12111 |
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por eng |
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https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/12111 https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/12111/6006 https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/12111/6707 https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/12111/11593 https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/12111/11932 https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/12111/12003 https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/12111/12060 |
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Direitos de Autor (c) 2020 Acta Médica Portuguesa info:eu-repo/semantics/openAccess |
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Direitos de Autor (c) 2020 Acta Médica Portuguesa |
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Ordem dos Médicos |
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Ordem dos Médicos |
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Acta Médica Portuguesa; Vol. 33 No. 7-8 (2020): July-August; 491-499 Acta Médica Portuguesa; Vol. 33 N.º 7-8 (2020): Julho-Agosto; 491-499 1646-0758 0870-399X reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
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