Neurolymphomatosis as primary presentation of extra-nodal NK/T-cell lymphoma, nasal type
Autor(a) principal: | |
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Data de Publicação: | 2024 |
Outros Autores: | , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10400.26/50742 |
Resumo: | Neurolymphomatosis (NL) describes an infiltration of cranial and peripheral nerves by lymphoma cells, most frequently in non-Hodgkin B-cell lymphoma. This clinical entity is rare and poses a challenging diagnosis. We describe a case of a 64-year-old female patient with NL associated with extra-nodal NK/T-cell lymphoma (ENKTL), nasal type, presenting as a painful progressive mononeuropathy multiplex with an oral cavity lesion. ENKTL is usually associated with Epstein-Barr virus (EBV) infection and rarely affects the central and peripheral nervous system. Lumbar puncture, magnetic resonance imaging (MRI), nerve biopsy, and 18F-fluorodeoxyglucose positron emission tomography (FDG-PET) help to establish the diagnosis. Thereby, NL should be considered in the differential diagnosis of painful progressive multiple neuropathies, even in patients without previous history of cancer. |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Neurolymphomatosis as primary presentation of extra-nodal NK/T-cell lymphoma, nasal typeLinfoma Extranodal de Células T-NKNeurolinfomatoseLymphoma, Extranodal NK-T-CellNeurolymphomatosisNeurolymphomatosis (NL) describes an infiltration of cranial and peripheral nerves by lymphoma cells, most frequently in non-Hodgkin B-cell lymphoma. This clinical entity is rare and poses a challenging diagnosis. We describe a case of a 64-year-old female patient with NL associated with extra-nodal NK/T-cell lymphoma (ENKTL), nasal type, presenting as a painful progressive mononeuropathy multiplex with an oral cavity lesion. ENKTL is usually associated with Epstein-Barr virus (EBV) infection and rarely affects the central and peripheral nervous system. Lumbar puncture, magnetic resonance imaging (MRI), nerve biopsy, and 18F-fluorodeoxyglucose positron emission tomography (FDG-PET) help to establish the diagnosis. Thereby, NL should be considered in the differential diagnosis of painful progressive multiple neuropathies, even in patients without previous history of cancer.Repositório ComumSilva, MISantos, PViegas, DMiranda, MMontes, VPita, FCarmona, C2024-04-30T21:42:53Z20242024-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.26/50742engNeurol Sci . 2024 Mar 12. doi: 10.1007/s10072-024-07445-4.10.1007/s10072-024-07445-4info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-05-04T10:10:16Zoai:comum.rcaap.pt:10400.26/50742Portal AgregadorONGhttps://www.rcaap.pt/oai/openairemluisa.alvim@gmail.comopendoar:71602024-05-04T10:10:16Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Neurolymphomatosis as primary presentation of extra-nodal NK/T-cell lymphoma, nasal type |
title |
Neurolymphomatosis as primary presentation of extra-nodal NK/T-cell lymphoma, nasal type |
spellingShingle |
Neurolymphomatosis as primary presentation of extra-nodal NK/T-cell lymphoma, nasal type Silva, MI Linfoma Extranodal de Células T-NK Neurolinfomatose Lymphoma, Extranodal NK-T-Cell Neurolymphomatosis |
title_short |
Neurolymphomatosis as primary presentation of extra-nodal NK/T-cell lymphoma, nasal type |
title_full |
Neurolymphomatosis as primary presentation of extra-nodal NK/T-cell lymphoma, nasal type |
title_fullStr |
Neurolymphomatosis as primary presentation of extra-nodal NK/T-cell lymphoma, nasal type |
title_full_unstemmed |
Neurolymphomatosis as primary presentation of extra-nodal NK/T-cell lymphoma, nasal type |
title_sort |
Neurolymphomatosis as primary presentation of extra-nodal NK/T-cell lymphoma, nasal type |
author |
Silva, MI |
author_facet |
Silva, MI Santos, P Viegas, D Miranda, M Montes, V Pita, F Carmona, C |
author_role |
author |
author2 |
Santos, P Viegas, D Miranda, M Montes, V Pita, F Carmona, C |
author2_role |
author author author author author author |
dc.contributor.none.fl_str_mv |
Repositório Comum |
dc.contributor.author.fl_str_mv |
Silva, MI Santos, P Viegas, D Miranda, M Montes, V Pita, F Carmona, C |
dc.subject.por.fl_str_mv |
Linfoma Extranodal de Células T-NK Neurolinfomatose Lymphoma, Extranodal NK-T-Cell Neurolymphomatosis |
topic |
Linfoma Extranodal de Células T-NK Neurolinfomatose Lymphoma, Extranodal NK-T-Cell Neurolymphomatosis |
description |
Neurolymphomatosis (NL) describes an infiltration of cranial and peripheral nerves by lymphoma cells, most frequently in non-Hodgkin B-cell lymphoma. This clinical entity is rare and poses a challenging diagnosis. We describe a case of a 64-year-old female patient with NL associated with extra-nodal NK/T-cell lymphoma (ENKTL), nasal type, presenting as a painful progressive mononeuropathy multiplex with an oral cavity lesion. ENKTL is usually associated with Epstein-Barr virus (EBV) infection and rarely affects the central and peripheral nervous system. Lumbar puncture, magnetic resonance imaging (MRI), nerve biopsy, and 18F-fluorodeoxyglucose positron emission tomography (FDG-PET) help to establish the diagnosis. Thereby, NL should be considered in the differential diagnosis of painful progressive multiple neuropathies, even in patients without previous history of cancer. |
publishDate |
2024 |
dc.date.none.fl_str_mv |
2024-04-30T21:42:53Z 2024 2024-01-01T00:00:00Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10400.26/50742 |
url |
http://hdl.handle.net/10400.26/50742 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Neurol Sci . 2024 Mar 12. doi: 10.1007/s10072-024-07445-4. 10.1007/s10072-024-07445-4 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
instname_str |
Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
instacron_str |
RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
repository.mail.fl_str_mv |
mluisa.alvim@gmail.com |
_version_ |
1817543358786043904 |