Neurolymphomatosis as primary presentation of extra-nodal NK/T-cell lymphoma, nasal type

Detalhes bibliográficos
Autor(a) principal: Silva, MI
Data de Publicação: 2024
Outros Autores: Santos, P, Viegas, D, Miranda, M, Montes, V, Pita, F, Carmona, C
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10400.26/50742
Resumo: Neurolymphomatosis (NL) describes an infiltration of cranial and peripheral nerves by lymphoma cells, most frequently in non-Hodgkin B-cell lymphoma. This clinical entity is rare and poses a challenging diagnosis. We describe a case of a 64-year-old female patient with NL associated with extra-nodal NK/T-cell lymphoma (ENKTL), nasal type, presenting as a painful progressive mononeuropathy multiplex with an oral cavity lesion. ENKTL is usually associated with Epstein-Barr virus (EBV) infection and rarely affects the central and peripheral nervous system. Lumbar puncture, magnetic resonance imaging (MRI), nerve biopsy, and 18F-fluorodeoxyglucose positron emission tomography (FDG-PET) help to establish the diagnosis. Thereby, NL should be considered in the differential diagnosis of painful progressive multiple neuropathies, even in patients without previous history of cancer.
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spelling Neurolymphomatosis as primary presentation of extra-nodal NK/T-cell lymphoma, nasal typeLinfoma Extranodal de Células T-NKNeurolinfomatoseLymphoma, Extranodal NK-T-CellNeurolymphomatosisNeurolymphomatosis (NL) describes an infiltration of cranial and peripheral nerves by lymphoma cells, most frequently in non-Hodgkin B-cell lymphoma. This clinical entity is rare and poses a challenging diagnosis. We describe a case of a 64-year-old female patient with NL associated with extra-nodal NK/T-cell lymphoma (ENKTL), nasal type, presenting as a painful progressive mononeuropathy multiplex with an oral cavity lesion. ENKTL is usually associated with Epstein-Barr virus (EBV) infection and rarely affects the central and peripheral nervous system. Lumbar puncture, magnetic resonance imaging (MRI), nerve biopsy, and 18F-fluorodeoxyglucose positron emission tomography (FDG-PET) help to establish the diagnosis. Thereby, NL should be considered in the differential diagnosis of painful progressive multiple neuropathies, even in patients without previous history of cancer.Repositório ComumSilva, MISantos, PViegas, DMiranda, MMontes, VPita, FCarmona, C2024-04-30T21:42:53Z20242024-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.26/50742engNeurol Sci . 2024 Mar 12. doi: 10.1007/s10072-024-07445-4.10.1007/s10072-024-07445-4info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-05-04T10:10:16Zoai:comum.rcaap.pt:10400.26/50742Portal AgregadorONGhttps://www.rcaap.pt/oai/openairemluisa.alvim@gmail.comopendoar:71602024-05-04T10:10:16Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Neurolymphomatosis as primary presentation of extra-nodal NK/T-cell lymphoma, nasal type
title Neurolymphomatosis as primary presentation of extra-nodal NK/T-cell lymphoma, nasal type
spellingShingle Neurolymphomatosis as primary presentation of extra-nodal NK/T-cell lymphoma, nasal type
Silva, MI
Linfoma Extranodal de Células T-NK
Neurolinfomatose
Lymphoma, Extranodal NK-T-Cell
Neurolymphomatosis
title_short Neurolymphomatosis as primary presentation of extra-nodal NK/T-cell lymphoma, nasal type
title_full Neurolymphomatosis as primary presentation of extra-nodal NK/T-cell lymphoma, nasal type
title_fullStr Neurolymphomatosis as primary presentation of extra-nodal NK/T-cell lymphoma, nasal type
title_full_unstemmed Neurolymphomatosis as primary presentation of extra-nodal NK/T-cell lymphoma, nasal type
title_sort Neurolymphomatosis as primary presentation of extra-nodal NK/T-cell lymphoma, nasal type
author Silva, MI
author_facet Silva, MI
Santos, P
Viegas, D
Miranda, M
Montes, V
Pita, F
Carmona, C
author_role author
author2 Santos, P
Viegas, D
Miranda, M
Montes, V
Pita, F
Carmona, C
author2_role author
author
author
author
author
author
dc.contributor.none.fl_str_mv Repositório Comum
dc.contributor.author.fl_str_mv Silva, MI
Santos, P
Viegas, D
Miranda, M
Montes, V
Pita, F
Carmona, C
dc.subject.por.fl_str_mv Linfoma Extranodal de Células T-NK
Neurolinfomatose
Lymphoma, Extranodal NK-T-Cell
Neurolymphomatosis
topic Linfoma Extranodal de Células T-NK
Neurolinfomatose
Lymphoma, Extranodal NK-T-Cell
Neurolymphomatosis
description Neurolymphomatosis (NL) describes an infiltration of cranial and peripheral nerves by lymphoma cells, most frequently in non-Hodgkin B-cell lymphoma. This clinical entity is rare and poses a challenging diagnosis. We describe a case of a 64-year-old female patient with NL associated with extra-nodal NK/T-cell lymphoma (ENKTL), nasal type, presenting as a painful progressive mononeuropathy multiplex with an oral cavity lesion. ENKTL is usually associated with Epstein-Barr virus (EBV) infection and rarely affects the central and peripheral nervous system. Lumbar puncture, magnetic resonance imaging (MRI), nerve biopsy, and 18F-fluorodeoxyglucose positron emission tomography (FDG-PET) help to establish the diagnosis. Thereby, NL should be considered in the differential diagnosis of painful progressive multiple neuropathies, even in patients without previous history of cancer.
publishDate 2024
dc.date.none.fl_str_mv 2024-04-30T21:42:53Z
2024
2024-01-01T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10400.26/50742
url http://hdl.handle.net/10400.26/50742
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Neurol Sci . 2024 Mar 12. doi: 10.1007/s10072-024-07445-4.
10.1007/s10072-024-07445-4
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
repository.mail.fl_str_mv mluisa.alvim@gmail.com
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