Alternative tissue engineering scaffolds based on starch: processing methodologies, morphology, degradation and mechanical properties

Detalhes bibliográficos
Autor(a) principal: Gomes, Manuela E.
Data de Publicação: 2002
Outros Autores: Godinho, J. S., Tchalamov, D., Cunha, A. M., Reis, R. L.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/1822/269
Resumo: http://www.sciencedirect.com/science/journal/09284931
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spelling Alternative tissue engineering scaffolds based on starch: processing methodologies, morphology, degradation and mechanical propertiesStarch-based polymersTissue engineeringBiodegradable scaffoldsScience & Technologyhttp://www.sciencedirect.com/science/journal/09284931An ideal tissue engineering scaffold must be designed from a polymer with an adequate degradation rate. The processing technique must allow for the preparation of 3-D scaffolds with controlled porosity and adequate pore sizes, as well as tissue matching mechanical properties and an appropriate biological response. This communication revises recent work that has been developed in our laboratories with the aim of producing 3-D polymeric structures (from starch-based blends) with adequate properties to be used as scaffolds for bone tissue engineering applications. Several processing methodologies were originally developed and optimised. Some of these methodologies were based on conventional melt-based processing routes, such as extrusion using blowing agents (BA) and compression moulding (combined with particulate leaching). Other developed technologies included solvent casting and particle leaching and an innovative in situ polymerization method. By means of using the described methodologies, it is possible to tailor the properties of the different scaffolds, namely their degradation, morphology and mechanical properties, for several applications in tissue engineering. Furthermore, the processing methodologies (including the blowing agents used in the melt-based technologies) described above do not affect the biocompatible behaviour of starch-based polymers. Therefore, scaffolds obtained from these materials by means of using one of the described methodologies may constitute an important alternative to the materials currently used in tissue engineering.Elsevier ScienceUniversidade do MinhoGomes, Manuela E.Godinho, J. S.Tchalamov, D.Cunha, A. M.Reis, R. L.20022002-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/1822/269eng"Materials Science and Engineering C". 20:1-2 (2002) 19–26.0928-493110.1016/S0928-4931(02)00008-5info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-07-21T12:35:36Zoai:repositorium.sdum.uminho.pt:1822/269Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T19:31:29.259075Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Alternative tissue engineering scaffolds based on starch: processing methodologies, morphology, degradation and mechanical properties
title Alternative tissue engineering scaffolds based on starch: processing methodologies, morphology, degradation and mechanical properties
spellingShingle Alternative tissue engineering scaffolds based on starch: processing methodologies, morphology, degradation and mechanical properties
Gomes, Manuela E.
Starch-based polymers
Tissue engineering
Biodegradable scaffolds
Science & Technology
title_short Alternative tissue engineering scaffolds based on starch: processing methodologies, morphology, degradation and mechanical properties
title_full Alternative tissue engineering scaffolds based on starch: processing methodologies, morphology, degradation and mechanical properties
title_fullStr Alternative tissue engineering scaffolds based on starch: processing methodologies, morphology, degradation and mechanical properties
title_full_unstemmed Alternative tissue engineering scaffolds based on starch: processing methodologies, morphology, degradation and mechanical properties
title_sort Alternative tissue engineering scaffolds based on starch: processing methodologies, morphology, degradation and mechanical properties
author Gomes, Manuela E.
author_facet Gomes, Manuela E.
Godinho, J. S.
Tchalamov, D.
Cunha, A. M.
Reis, R. L.
author_role author
author2 Godinho, J. S.
Tchalamov, D.
Cunha, A. M.
Reis, R. L.
author2_role author
author
author
author
dc.contributor.none.fl_str_mv Universidade do Minho
dc.contributor.author.fl_str_mv Gomes, Manuela E.
Godinho, J. S.
Tchalamov, D.
Cunha, A. M.
Reis, R. L.
dc.subject.por.fl_str_mv Starch-based polymers
Tissue engineering
Biodegradable scaffolds
Science & Technology
topic Starch-based polymers
Tissue engineering
Biodegradable scaffolds
Science & Technology
description http://www.sciencedirect.com/science/journal/09284931
publishDate 2002
dc.date.none.fl_str_mv 2002
2002-01-01T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/1822/269
url http://hdl.handle.net/1822/269
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv "Materials Science and Engineering C". 20:1-2 (2002) 19–26.
0928-4931
10.1016/S0928-4931(02)00008-5
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Elsevier Science
publisher.none.fl_str_mv Elsevier Science
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
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reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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