Effects of large pressure amplitude low frequency noise in the parotid gland perivasculo-ductal connective tissue

Detalhes bibliográficos
Autor(a) principal: Oliveira, Pedro
Data de Publicação: 2013
Outros Autores: Brito, José, Mendes, José João, Fonseca, Jorge da, Águas, Artur, Martins dos Santos, José
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10400.26/6223
Resumo: "Introduction: In tissues and organs exposed to large pressure amplitude low frequency noise fibrosis occurs in the absence of inflammatory signs, which is thought to be a protective response. In the parotid gland the perivasculo-ductal connective tissue surrounds arteries, veins and the ductal tree. Perivasculo-ductal connective tissue is believed to function as a mechanical stabilizer of the glandular tissue. Material and Methods: In order to quantify the proliferation of perivasculo-ductal connective tissue in large pressure amplitude low frequency noise-exposed rats we used sixty Wistar rats which were equally divided into 6 groups. One group kept in silence, and the remaining five exposed to continuous large pressure amplitude low frequency noise: g1-168h (1 week); g2-504h (3 weeks); g3-840h (5 weeks); g4-1512h (9 weeks); and g5-2184h (13 weeks). After exposure, parotid glands were removed and the perivasculo-ductal connective tissue area was measured in all groups. We applied ANOVA statistical analysis, using SPSS 13.0. Results: The global trend is an increase in the average perivasculo-ductal connective tissue areas, that develops linearly and significantly with large pressure amplitude low frequency noise exposure time (p < 0.001). Discussion: It has been suggested that the biological response to large pressure amplitude low frequency noise exposure is associated with the need to maintain structural integrity. The structural reinforcement would be achieved by increased perivasculo-ductal connective tissue. Conclusions: Hence, these results show that in response to large pressure amplitude low frequency noise exposure, rat parotid glands increase their perivasculo-ductal connective tissue."
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spelling Effects of large pressure amplitude low frequency noise in the parotid gland perivasculo-ductal connective tissueFibrillar collagensConnective tissueParotid glandRats"Introduction: In tissues and organs exposed to large pressure amplitude low frequency noise fibrosis occurs in the absence of inflammatory signs, which is thought to be a protective response. In the parotid gland the perivasculo-ductal connective tissue surrounds arteries, veins and the ductal tree. Perivasculo-ductal connective tissue is believed to function as a mechanical stabilizer of the glandular tissue. Material and Methods: In order to quantify the proliferation of perivasculo-ductal connective tissue in large pressure amplitude low frequency noise-exposed rats we used sixty Wistar rats which were equally divided into 6 groups. One group kept in silence, and the remaining five exposed to continuous large pressure amplitude low frequency noise: g1-168h (1 week); g2-504h (3 weeks); g3-840h (5 weeks); g4-1512h (9 weeks); and g5-2184h (13 weeks). After exposure, parotid glands were removed and the perivasculo-ductal connective tissue area was measured in all groups. We applied ANOVA statistical analysis, using SPSS 13.0. Results: The global trend is an increase in the average perivasculo-ductal connective tissue areas, that develops linearly and significantly with large pressure amplitude low frequency noise exposure time (p < 0.001). Discussion: It has been suggested that the biological response to large pressure amplitude low frequency noise exposure is associated with the need to maintain structural integrity. The structural reinforcement would be achieved by increased perivasculo-ductal connective tissue. Conclusions: Hence, these results show that in response to large pressure amplitude low frequency noise exposure, rat parotid glands increase their perivasculo-ductal connective tissue."Ordem dos Médicos (Portugal)Repositório ComumOliveira, PedroBrito, JoséMendes, José JoãoFonseca, Jorge daÁguas, ArturMartins dos Santos, José2014-04-17T13:33:26Z2013-05-01T00:00:00Z2013-05-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.26/6223engActa Med Port 2013 May-Jun;26(3):237-2420870-399Xinfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2022-10-06T14:51:26Zoai:comum.rcaap.pt:10400.26/6223Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T15:06:03.355084Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Effects of large pressure amplitude low frequency noise in the parotid gland perivasculo-ductal connective tissue
title Effects of large pressure amplitude low frequency noise in the parotid gland perivasculo-ductal connective tissue
spellingShingle Effects of large pressure amplitude low frequency noise in the parotid gland perivasculo-ductal connective tissue
Oliveira, Pedro
Fibrillar collagens
Connective tissue
Parotid gland
Rats
title_short Effects of large pressure amplitude low frequency noise in the parotid gland perivasculo-ductal connective tissue
title_full Effects of large pressure amplitude low frequency noise in the parotid gland perivasculo-ductal connective tissue
title_fullStr Effects of large pressure amplitude low frequency noise in the parotid gland perivasculo-ductal connective tissue
title_full_unstemmed Effects of large pressure amplitude low frequency noise in the parotid gland perivasculo-ductal connective tissue
title_sort Effects of large pressure amplitude low frequency noise in the parotid gland perivasculo-ductal connective tissue
author Oliveira, Pedro
author_facet Oliveira, Pedro
Brito, José
Mendes, José João
Fonseca, Jorge da
Águas, Artur
Martins dos Santos, José
author_role author
author2 Brito, José
Mendes, José João
Fonseca, Jorge da
Águas, Artur
Martins dos Santos, José
author2_role author
author
author
author
author
dc.contributor.none.fl_str_mv Repositório Comum
dc.contributor.author.fl_str_mv Oliveira, Pedro
Brito, José
Mendes, José João
Fonseca, Jorge da
Águas, Artur
Martins dos Santos, José
dc.subject.por.fl_str_mv Fibrillar collagens
Connective tissue
Parotid gland
Rats
topic Fibrillar collagens
Connective tissue
Parotid gland
Rats
description "Introduction: In tissues and organs exposed to large pressure amplitude low frequency noise fibrosis occurs in the absence of inflammatory signs, which is thought to be a protective response. In the parotid gland the perivasculo-ductal connective tissue surrounds arteries, veins and the ductal tree. Perivasculo-ductal connective tissue is believed to function as a mechanical stabilizer of the glandular tissue. Material and Methods: In order to quantify the proliferation of perivasculo-ductal connective tissue in large pressure amplitude low frequency noise-exposed rats we used sixty Wistar rats which were equally divided into 6 groups. One group kept in silence, and the remaining five exposed to continuous large pressure amplitude low frequency noise: g1-168h (1 week); g2-504h (3 weeks); g3-840h (5 weeks); g4-1512h (9 weeks); and g5-2184h (13 weeks). After exposure, parotid glands were removed and the perivasculo-ductal connective tissue area was measured in all groups. We applied ANOVA statistical analysis, using SPSS 13.0. Results: The global trend is an increase in the average perivasculo-ductal connective tissue areas, that develops linearly and significantly with large pressure amplitude low frequency noise exposure time (p < 0.001). Discussion: It has been suggested that the biological response to large pressure amplitude low frequency noise exposure is associated with the need to maintain structural integrity. The structural reinforcement would be achieved by increased perivasculo-ductal connective tissue. Conclusions: Hence, these results show that in response to large pressure amplitude low frequency noise exposure, rat parotid glands increase their perivasculo-ductal connective tissue."
publishDate 2013
dc.date.none.fl_str_mv 2013-05-01T00:00:00Z
2013-05-01T00:00:00Z
2014-04-17T13:33:26Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10400.26/6223
url http://hdl.handle.net/10400.26/6223
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Acta Med Port 2013 May-Jun;26(3):237-242
0870-399X
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Ordem dos Médicos (Portugal)
publisher.none.fl_str_mv Ordem dos Médicos (Portugal)
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
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instacron:RCAAP
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instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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