The effect of the quantitative variation of autologous spongy bone graft applied for bone regeneration in an experimental model of tibia osteotomy.

Detalhes bibliográficos
Autor(a) principal: Dias, Maria Isabel
Data de Publicação: 2007
Outros Autores: Lourenço, Paulo, Rodrigues, Adriano, Azevedo, Jorge, Viegas, Carlos, Ferreira, António, Cabrita, António Silvério
Tipo de documento: Artigo
Idioma: por
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/833
Resumo: This study aimed at studying the influence of the quantitative variation of the autologous spongy bone graft on its osteogenic properties by virtue of the fact that its attainment has inconveniences of significant morbidity at local donor level and the limited quantity of grafting able to be obtained. Recourse was made to an osteotomy model for this purpose with the removal of a small 4 mm segment at the mid-diaphysis of the left tibia of twenty one sheep, stabilised by an osteosynthesis plate on which different quantities of autografting spongy bone were applied so that the referred bone defect (1) would not to be completely filled (1.5 g), (2) would be filled without any compression (3 g) and (3) would be filled with an excessive quantity (5 g) (n=5/each group). (4) A control osteotomy (n=6) was also carried out where the bone defect remained empty. Comparison of the evolution of bone regeneration during the postoperative period of 12 weeks was carried out by means of conventional radiographic exams and optical densitometry analysis and by radiological bone densitometry (DEXA--Dual-Energy X-ray Absorptiometry), bone histomorphometry and histological analysis after the animals' euthanasia. Optical density was significantly affected (p
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spelling The effect of the quantitative variation of autologous spongy bone graft applied for bone regeneration in an experimental model of tibia osteotomy.O efeito da quantidade do enxerto de osso esponjoso autólogo utilizado na regeneração óssea num modelo experimental de osteotomia da tíbia.This study aimed at studying the influence of the quantitative variation of the autologous spongy bone graft on its osteogenic properties by virtue of the fact that its attainment has inconveniences of significant morbidity at local donor level and the limited quantity of grafting able to be obtained. Recourse was made to an osteotomy model for this purpose with the removal of a small 4 mm segment at the mid-diaphysis of the left tibia of twenty one sheep, stabilised by an osteosynthesis plate on which different quantities of autografting spongy bone were applied so that the referred bone defect (1) would not to be completely filled (1.5 g), (2) would be filled without any compression (3 g) and (3) would be filled with an excessive quantity (5 g) (n=5/each group). (4) A control osteotomy (n=6) was also carried out where the bone defect remained empty. Comparison of the evolution of bone regeneration during the postoperative period of 12 weeks was carried out by means of conventional radiographic exams and optical densitometry analysis and by radiological bone densitometry (DEXA--Dual-Energy X-ray Absorptiometry), bone histomorphometry and histological analysis after the animals' euthanasia. Optical density was significantly affected (pThis study aimed at studying the influence of the quantitative variation of the autologous spongy bone graft on its osteogenic properties by virtue of the fact that its attainment has inconveniences of significant morbidity at local donor level and the limited quantity of grafting able to be obtained. Recourse was made to an osteotomy model for this purpose with the removal of a small 4 mm segment at the mid-diaphysis of the left tibia of twenty one sheep, stabilised by an osteosynthesis plate on which different quantities of autografting spongy bone were applied so that the referred bone defect (1) would not to be completely filled (1.5 g), (2) would be filled without any compression (3 g) and (3) would be filled with an excessive quantity (5 g) (n=5/each group). (4) A control osteotomy (n=6) was also carried out where the bone defect remained empty. Comparison of the evolution of bone regeneration during the postoperative period of 12 weeks was carried out by means of conventional radiographic exams and optical densitometry analysis and by radiological bone densitometry (DEXA--Dual-Energy X-ray Absorptiometry), bone histomorphometry and histological analysis after the animals' euthanasia. Optical density was significantly affected (pOrdem dos Médicos2007-05-23info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttps://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/833oai:ojs.www.actamedicaportuguesa.com:article/833Acta Médica Portuguesa; Vol. 20 No. 1 (2007): January-February; 37-46Acta Médica Portuguesa; Vol. 20 N.º 1 (2007): Janeiro-Fevereiro; 37-461646-07580870-399Xreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAPporhttps://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/833https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/833/509Dias, Maria IsabelLourenço, PauloRodrigues, AdrianoAzevedo, JorgeViegas, CarlosFerreira, AntónioCabrita, António Silvérioinfo:eu-repo/semantics/openAccess2022-12-20T10:57:00Zoai:ojs.www.actamedicaportuguesa.com:article/833Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T16:16:47.364026Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv The effect of the quantitative variation of autologous spongy bone graft applied for bone regeneration in an experimental model of tibia osteotomy.
O efeito da quantidade do enxerto de osso esponjoso autólogo utilizado na regeneração óssea num modelo experimental de osteotomia da tíbia.
title The effect of the quantitative variation of autologous spongy bone graft applied for bone regeneration in an experimental model of tibia osteotomy.
spellingShingle The effect of the quantitative variation of autologous spongy bone graft applied for bone regeneration in an experimental model of tibia osteotomy.
Dias, Maria Isabel
title_short The effect of the quantitative variation of autologous spongy bone graft applied for bone regeneration in an experimental model of tibia osteotomy.
title_full The effect of the quantitative variation of autologous spongy bone graft applied for bone regeneration in an experimental model of tibia osteotomy.
title_fullStr The effect of the quantitative variation of autologous spongy bone graft applied for bone regeneration in an experimental model of tibia osteotomy.
title_full_unstemmed The effect of the quantitative variation of autologous spongy bone graft applied for bone regeneration in an experimental model of tibia osteotomy.
title_sort The effect of the quantitative variation of autologous spongy bone graft applied for bone regeneration in an experimental model of tibia osteotomy.
author Dias, Maria Isabel
author_facet Dias, Maria Isabel
Lourenço, Paulo
Rodrigues, Adriano
Azevedo, Jorge
Viegas, Carlos
Ferreira, António
Cabrita, António Silvério
author_role author
author2 Lourenço, Paulo
Rodrigues, Adriano
Azevedo, Jorge
Viegas, Carlos
Ferreira, António
Cabrita, António Silvério
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Dias, Maria Isabel
Lourenço, Paulo
Rodrigues, Adriano
Azevedo, Jorge
Viegas, Carlos
Ferreira, António
Cabrita, António Silvério
description This study aimed at studying the influence of the quantitative variation of the autologous spongy bone graft on its osteogenic properties by virtue of the fact that its attainment has inconveniences of significant morbidity at local donor level and the limited quantity of grafting able to be obtained. Recourse was made to an osteotomy model for this purpose with the removal of a small 4 mm segment at the mid-diaphysis of the left tibia of twenty one sheep, stabilised by an osteosynthesis plate on which different quantities of autografting spongy bone were applied so that the referred bone defect (1) would not to be completely filled (1.5 g), (2) would be filled without any compression (3 g) and (3) would be filled with an excessive quantity (5 g) (n=5/each group). (4) A control osteotomy (n=6) was also carried out where the bone defect remained empty. Comparison of the evolution of bone regeneration during the postoperative period of 12 weeks was carried out by means of conventional radiographic exams and optical densitometry analysis and by radiological bone densitometry (DEXA--Dual-Energy X-ray Absorptiometry), bone histomorphometry and histological analysis after the animals' euthanasia. Optical density was significantly affected (p
publishDate 2007
dc.date.none.fl_str_mv 2007-05-23
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https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/833/509
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dc.publisher.none.fl_str_mv Ordem dos Médicos
publisher.none.fl_str_mv Ordem dos Médicos
dc.source.none.fl_str_mv Acta Médica Portuguesa; Vol. 20 No. 1 (2007): January-February; 37-46
Acta Médica Portuguesa; Vol. 20 N.º 1 (2007): Janeiro-Fevereiro; 37-46
1646-0758
0870-399X
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