The effect of the quantitative variation of autologous spongy bone graft applied for bone regeneration in an experimental model of tibia osteotomy.
Autor(a) principal: | |
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Data de Publicação: | 2007 |
Outros Autores: | , , , , , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/833 |
Resumo: | This study aimed at studying the influence of the quantitative variation of the autologous spongy bone graft on its osteogenic properties by virtue of the fact that its attainment has inconveniences of significant morbidity at local donor level and the limited quantity of grafting able to be obtained. Recourse was made to an osteotomy model for this purpose with the removal of a small 4 mm segment at the mid-diaphysis of the left tibia of twenty one sheep, stabilised by an osteosynthesis plate on which different quantities of autografting spongy bone were applied so that the referred bone defect (1) would not to be completely filled (1.5 g), (2) would be filled without any compression (3 g) and (3) would be filled with an excessive quantity (5 g) (n=5/each group). (4) A control osteotomy (n=6) was also carried out where the bone defect remained empty. Comparison of the evolution of bone regeneration during the postoperative period of 12 weeks was carried out by means of conventional radiographic exams and optical densitometry analysis and by radiological bone densitometry (DEXA--Dual-Energy X-ray Absorptiometry), bone histomorphometry and histological analysis after the animals' euthanasia. Optical density was significantly affected (p |
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The effect of the quantitative variation of autologous spongy bone graft applied for bone regeneration in an experimental model of tibia osteotomy.O efeito da quantidade do enxerto de osso esponjoso autólogo utilizado na regeneração óssea num modelo experimental de osteotomia da tíbia.This study aimed at studying the influence of the quantitative variation of the autologous spongy bone graft on its osteogenic properties by virtue of the fact that its attainment has inconveniences of significant morbidity at local donor level and the limited quantity of grafting able to be obtained. Recourse was made to an osteotomy model for this purpose with the removal of a small 4 mm segment at the mid-diaphysis of the left tibia of twenty one sheep, stabilised by an osteosynthesis plate on which different quantities of autografting spongy bone were applied so that the referred bone defect (1) would not to be completely filled (1.5 g), (2) would be filled without any compression (3 g) and (3) would be filled with an excessive quantity (5 g) (n=5/each group). (4) A control osteotomy (n=6) was also carried out where the bone defect remained empty. Comparison of the evolution of bone regeneration during the postoperative period of 12 weeks was carried out by means of conventional radiographic exams and optical densitometry analysis and by radiological bone densitometry (DEXA--Dual-Energy X-ray Absorptiometry), bone histomorphometry and histological analysis after the animals' euthanasia. Optical density was significantly affected (pThis study aimed at studying the influence of the quantitative variation of the autologous spongy bone graft on its osteogenic properties by virtue of the fact that its attainment has inconveniences of significant morbidity at local donor level and the limited quantity of grafting able to be obtained. Recourse was made to an osteotomy model for this purpose with the removal of a small 4 mm segment at the mid-diaphysis of the left tibia of twenty one sheep, stabilised by an osteosynthesis plate on which different quantities of autografting spongy bone were applied so that the referred bone defect (1) would not to be completely filled (1.5 g), (2) would be filled without any compression (3 g) and (3) would be filled with an excessive quantity (5 g) (n=5/each group). (4) A control osteotomy (n=6) was also carried out where the bone defect remained empty. Comparison of the evolution of bone regeneration during the postoperative period of 12 weeks was carried out by means of conventional radiographic exams and optical densitometry analysis and by radiological bone densitometry (DEXA--Dual-Energy X-ray Absorptiometry), bone histomorphometry and histological analysis after the animals' euthanasia. Optical density was significantly affected (pOrdem dos Médicos2007-05-23info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttps://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/833oai:ojs.www.actamedicaportuguesa.com:article/833Acta Médica Portuguesa; Vol. 20 No. 1 (2007): January-February; 37-46Acta Médica Portuguesa; Vol. 20 N.º 1 (2007): Janeiro-Fevereiro; 37-461646-07580870-399Xreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAPporhttps://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/833https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/833/509Dias, Maria IsabelLourenço, PauloRodrigues, AdrianoAzevedo, JorgeViegas, CarlosFerreira, AntónioCabrita, António Silvérioinfo:eu-repo/semantics/openAccess2022-12-20T10:57:00Zoai:ojs.www.actamedicaportuguesa.com:article/833Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T16:16:47.364026Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
The effect of the quantitative variation of autologous spongy bone graft applied for bone regeneration in an experimental model of tibia osteotomy. O efeito da quantidade do enxerto de osso esponjoso autólogo utilizado na regeneração óssea num modelo experimental de osteotomia da tíbia. |
title |
The effect of the quantitative variation of autologous spongy bone graft applied for bone regeneration in an experimental model of tibia osteotomy. |
spellingShingle |
The effect of the quantitative variation of autologous spongy bone graft applied for bone regeneration in an experimental model of tibia osteotomy. Dias, Maria Isabel |
title_short |
The effect of the quantitative variation of autologous spongy bone graft applied for bone regeneration in an experimental model of tibia osteotomy. |
title_full |
The effect of the quantitative variation of autologous spongy bone graft applied for bone regeneration in an experimental model of tibia osteotomy. |
title_fullStr |
The effect of the quantitative variation of autologous spongy bone graft applied for bone regeneration in an experimental model of tibia osteotomy. |
title_full_unstemmed |
The effect of the quantitative variation of autologous spongy bone graft applied for bone regeneration in an experimental model of tibia osteotomy. |
title_sort |
The effect of the quantitative variation of autologous spongy bone graft applied for bone regeneration in an experimental model of tibia osteotomy. |
author |
Dias, Maria Isabel |
author_facet |
Dias, Maria Isabel Lourenço, Paulo Rodrigues, Adriano Azevedo, Jorge Viegas, Carlos Ferreira, António Cabrita, António Silvério |
author_role |
author |
author2 |
Lourenço, Paulo Rodrigues, Adriano Azevedo, Jorge Viegas, Carlos Ferreira, António Cabrita, António Silvério |
author2_role |
author author author author author author |
dc.contributor.author.fl_str_mv |
Dias, Maria Isabel Lourenço, Paulo Rodrigues, Adriano Azevedo, Jorge Viegas, Carlos Ferreira, António Cabrita, António Silvério |
description |
This study aimed at studying the influence of the quantitative variation of the autologous spongy bone graft on its osteogenic properties by virtue of the fact that its attainment has inconveniences of significant morbidity at local donor level and the limited quantity of grafting able to be obtained. Recourse was made to an osteotomy model for this purpose with the removal of a small 4 mm segment at the mid-diaphysis of the left tibia of twenty one sheep, stabilised by an osteosynthesis plate on which different quantities of autografting spongy bone were applied so that the referred bone defect (1) would not to be completely filled (1.5 g), (2) would be filled without any compression (3 g) and (3) would be filled with an excessive quantity (5 g) (n=5/each group). (4) A control osteotomy (n=6) was also carried out where the bone defect remained empty. Comparison of the evolution of bone regeneration during the postoperative period of 12 weeks was carried out by means of conventional radiographic exams and optical densitometry analysis and by radiological bone densitometry (DEXA--Dual-Energy X-ray Absorptiometry), bone histomorphometry and histological analysis after the animals' euthanasia. Optical density was significantly affected (p |
publishDate |
2007 |
dc.date.none.fl_str_mv |
2007-05-23 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/833 oai:ojs.www.actamedicaportuguesa.com:article/833 |
url |
https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/833 |
identifier_str_mv |
oai:ojs.www.actamedicaportuguesa.com:article/833 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/833 https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/833/509 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Ordem dos Médicos |
publisher.none.fl_str_mv |
Ordem dos Médicos |
dc.source.none.fl_str_mv |
Acta Médica Portuguesa; Vol. 20 No. 1 (2007): January-February; 37-46 Acta Médica Portuguesa; Vol. 20 N.º 1 (2007): Janeiro-Fevereiro; 37-46 1646-0758 0870-399X reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
instname_str |
Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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