Dispersals and genetic adaptation of Bantu-speaking populations in Africa and North America
Autor(a) principal: | |
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Data de Publicação: | 2017 |
Outros Autores: | , , , , , , , , , , , , , , , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10216/109265 |
Resumo: | Bantu languages are spoken by about 310 million Africans, yet the genetic history of Bantu-speaking populations remains largely unexplored. We generated genomic data for 1318 individuals from 35 populations in western central Africa, where Bantu languages originated. We found that early Bantu speakers first moved southward, through the equatorial rainforest, before spreading toward eastern and southern Africa. We also found that genetic adaptation of Bantu speakers was facilitated by admixture with local populations, particularly for the HLA and LCT loci. Finally, we identified a major contribution of western central African Bantu speakers to the ancestry of African Americans, whose genomes present no strong signals of natural selection. Together, these results highlight the contribution of Bantu-speaking peoples to the complex genetic history of Africans and African Americans. |
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Dispersals and genetic adaptation of Bantu-speaking populations in Africa and North AmericaAdmixtureGenomeAncestryHistoryExpansionSelectionBantu languages are spoken by about 310 million Africans, yet the genetic history of Bantu-speaking populations remains largely unexplored. We generated genomic data for 1318 individuals from 35 populations in western central Africa, where Bantu languages originated. We found that early Bantu speakers first moved southward, through the equatorial rainforest, before spreading toward eastern and southern Africa. We also found that genetic adaptation of Bantu speakers was facilitated by admixture with local populations, particularly for the HLA and LCT loci. Finally, we identified a major contribution of western central African Bantu speakers to the ancestry of African Americans, whose genomes present no strong signals of natural selection. Together, these results highlight the contribution of Bantu-speaking peoples to the complex genetic history of Africans and African Americans.American Association for the Advancement of Science20172017-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfapplication/pdfapplication/vnd.openxmlformats-officedocument.spreadsheetml.sheethttp://hdl.handle.net/10216/109265eng0036-807510.1126/science.aal1988Patin, ELopez, MGrollemund, RVerdu, PHarmant, CQuach, HLaval, GPerry, GHBarreiro, LBFroment, AHeyer, EMassougbodji, AFortes-Lima, CMigot-Nabias, FBellis, GDugoujon, JMPereira, JBFernandes, VPereira, LVan der Veen, LMouguiama-Daouda, PBustamante, CDHombert, JMQuintana-Murci, Linfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-11-29T15:28:39Zoai:repositorio-aberto.up.pt:10216/109265Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T00:24:32.416747Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Dispersals and genetic adaptation of Bantu-speaking populations in Africa and North America |
title |
Dispersals and genetic adaptation of Bantu-speaking populations in Africa and North America |
spellingShingle |
Dispersals and genetic adaptation of Bantu-speaking populations in Africa and North America Patin, E Admixture Genome Ancestry History Expansion Selection |
title_short |
Dispersals and genetic adaptation of Bantu-speaking populations in Africa and North America |
title_full |
Dispersals and genetic adaptation of Bantu-speaking populations in Africa and North America |
title_fullStr |
Dispersals and genetic adaptation of Bantu-speaking populations in Africa and North America |
title_full_unstemmed |
Dispersals and genetic adaptation of Bantu-speaking populations in Africa and North America |
title_sort |
Dispersals and genetic adaptation of Bantu-speaking populations in Africa and North America |
author |
Patin, E |
author_facet |
Patin, E Lopez, M Grollemund, R Verdu, P Harmant, C Quach, H Laval, G Perry, GH Barreiro, LB Froment, A Heyer, E Massougbodji, A Fortes-Lima, C Migot-Nabias, F Bellis, G Dugoujon, JM Pereira, JB Fernandes, V Pereira, L Van der Veen, L Mouguiama-Daouda, P Bustamante, CD Hombert, JM Quintana-Murci, L |
author_role |
author |
author2 |
Lopez, M Grollemund, R Verdu, P Harmant, C Quach, H Laval, G Perry, GH Barreiro, LB Froment, A Heyer, E Massougbodji, A Fortes-Lima, C Migot-Nabias, F Bellis, G Dugoujon, JM Pereira, JB Fernandes, V Pereira, L Van der Veen, L Mouguiama-Daouda, P Bustamante, CD Hombert, JM Quintana-Murci, L |
author2_role |
author author author author author author author author author author author author author author author author author author author author author author author |
dc.contributor.author.fl_str_mv |
Patin, E Lopez, M Grollemund, R Verdu, P Harmant, C Quach, H Laval, G Perry, GH Barreiro, LB Froment, A Heyer, E Massougbodji, A Fortes-Lima, C Migot-Nabias, F Bellis, G Dugoujon, JM Pereira, JB Fernandes, V Pereira, L Van der Veen, L Mouguiama-Daouda, P Bustamante, CD Hombert, JM Quintana-Murci, L |
dc.subject.por.fl_str_mv |
Admixture Genome Ancestry History Expansion Selection |
topic |
Admixture Genome Ancestry History Expansion Selection |
description |
Bantu languages are spoken by about 310 million Africans, yet the genetic history of Bantu-speaking populations remains largely unexplored. We generated genomic data for 1318 individuals from 35 populations in western central Africa, where Bantu languages originated. We found that early Bantu speakers first moved southward, through the equatorial rainforest, before spreading toward eastern and southern Africa. We also found that genetic adaptation of Bantu speakers was facilitated by admixture with local populations, particularly for the HLA and LCT loci. Finally, we identified a major contribution of western central African Bantu speakers to the ancestry of African Americans, whose genomes present no strong signals of natural selection. Together, these results highlight the contribution of Bantu-speaking peoples to the complex genetic history of Africans and African Americans. |
publishDate |
2017 |
dc.date.none.fl_str_mv |
2017 2017-01-01T00:00:00Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10216/109265 |
url |
http://hdl.handle.net/10216/109265 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
0036-8075 10.1126/science.aal1988 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf application/pdf application/vnd.openxmlformats-officedocument.spreadsheetml.sheet |
dc.publisher.none.fl_str_mv |
American Association for the Advancement of Science |
publisher.none.fl_str_mv |
American Association for the Advancement of Science |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
instacron_str |
RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
repository.mail.fl_str_mv |
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1799136160475250688 |