A systematic scoping review of the genetic ancestry of the Brazilian population

Detalhes bibliográficos
Autor(a) principal: Souza,Aracele Maria de
Data de Publicação: 2019
Outros Autores: Resende,Sarah Stela, Sousa,Taís Nóbrega de, Brito,Cristiana Ferreira Alves de
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Genetics and Molecular Biology
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572019000400495
Resumo: Abstract The genetic background of the Brazilian population is mainly characterized by three parental populations: European, African, and Native American. The aim of this study was to overview the genetic ancestry estimates for different Brazilian geographic regions and analyze factors involved in these estimates. In this systematic scoping review were included 51 studies, comprehending 81 populations of 19 states from five regions of Brazil. To reduce the potential of bias from studies with different sampling methods, we calculated the mean genetic ancestry weighted by the number of individuals. The weighted mean proportions of European, African, and Native American ancestries were 68.1%, 19.6%, and 11.6%, respectively. At the regional level, the highest European contribution occurred in the South, while the highest African and Native American contributions occurred in the Northeastern and Northern regions, respectively. Among states in the Northeast region, Bahia and Ceará showed significant differences, suggesting distinct demographic histories. This review contributes for a broader understanding of the Brazilian ancestry and indicates that the ancestry estimates are influenced by the type of molecular marker and the sampling method.
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spelling A systematic scoping review of the genetic ancestry of the Brazilian populationScoping reviewgenetic ancestryBrazilian populationgenetic admixtureAbstract The genetic background of the Brazilian population is mainly characterized by three parental populations: European, African, and Native American. The aim of this study was to overview the genetic ancestry estimates for different Brazilian geographic regions and analyze factors involved in these estimates. In this systematic scoping review were included 51 studies, comprehending 81 populations of 19 states from five regions of Brazil. To reduce the potential of bias from studies with different sampling methods, we calculated the mean genetic ancestry weighted by the number of individuals. The weighted mean proportions of European, African, and Native American ancestries were 68.1%, 19.6%, and 11.6%, respectively. At the regional level, the highest European contribution occurred in the South, while the highest African and Native American contributions occurred in the Northeastern and Northern regions, respectively. Among states in the Northeast region, Bahia and Ceará showed significant differences, suggesting distinct demographic histories. This review contributes for a broader understanding of the Brazilian ancestry and indicates that the ancestry estimates are influenced by the type of molecular marker and the sampling method.Sociedade Brasileira de Genética2019-09-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572019000400495Genetics and Molecular Biology v.42 n.3 2019reponame:Genetics and Molecular Biologyinstname:Sociedade Brasileira de Genética (SBG)instacron:SBG10.1590/1678-4685-gmb-2018-0076info:eu-repo/semantics/openAccessSouza,Aracele Maria deResende,Sarah StelaSousa,Taís Nóbrega deBrito,Cristiana Ferreira Alves deeng2019-11-29T00:00:00Zoai:scielo:S1415-47572019000400495Revistahttp://www.gmb.org.br/ONGhttps://old.scielo.br/oai/scielo-oai.php||editor@gmb.org.br1678-46851415-4757opendoar:2019-11-29T00:00Genetics and Molecular Biology - Sociedade Brasileira de Genética (SBG)false
dc.title.none.fl_str_mv A systematic scoping review of the genetic ancestry of the Brazilian population
title A systematic scoping review of the genetic ancestry of the Brazilian population
spellingShingle A systematic scoping review of the genetic ancestry of the Brazilian population
Souza,Aracele Maria de
Scoping review
genetic ancestry
Brazilian population
genetic admixture
title_short A systematic scoping review of the genetic ancestry of the Brazilian population
title_full A systematic scoping review of the genetic ancestry of the Brazilian population
title_fullStr A systematic scoping review of the genetic ancestry of the Brazilian population
title_full_unstemmed A systematic scoping review of the genetic ancestry of the Brazilian population
title_sort A systematic scoping review of the genetic ancestry of the Brazilian population
author Souza,Aracele Maria de
author_facet Souza,Aracele Maria de
Resende,Sarah Stela
Sousa,Taís Nóbrega de
Brito,Cristiana Ferreira Alves de
author_role author
author2 Resende,Sarah Stela
Sousa,Taís Nóbrega de
Brito,Cristiana Ferreira Alves de
author2_role author
author
author
dc.contributor.author.fl_str_mv Souza,Aracele Maria de
Resende,Sarah Stela
Sousa,Taís Nóbrega de
Brito,Cristiana Ferreira Alves de
dc.subject.por.fl_str_mv Scoping review
genetic ancestry
Brazilian population
genetic admixture
topic Scoping review
genetic ancestry
Brazilian population
genetic admixture
description Abstract The genetic background of the Brazilian population is mainly characterized by three parental populations: European, African, and Native American. The aim of this study was to overview the genetic ancestry estimates for different Brazilian geographic regions and analyze factors involved in these estimates. In this systematic scoping review were included 51 studies, comprehending 81 populations of 19 states from five regions of Brazil. To reduce the potential of bias from studies with different sampling methods, we calculated the mean genetic ancestry weighted by the number of individuals. The weighted mean proportions of European, African, and Native American ancestries were 68.1%, 19.6%, and 11.6%, respectively. At the regional level, the highest European contribution occurred in the South, while the highest African and Native American contributions occurred in the Northeastern and Northern regions, respectively. Among states in the Northeast region, Bahia and Ceará showed significant differences, suggesting distinct demographic histories. This review contributes for a broader understanding of the Brazilian ancestry and indicates that the ancestry estimates are influenced by the type of molecular marker and the sampling method.
publishDate 2019
dc.date.none.fl_str_mv 2019-09-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572019000400495
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572019000400495
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/1678-4685-gmb-2018-0076
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Genética
publisher.none.fl_str_mv Sociedade Brasileira de Genética
dc.source.none.fl_str_mv Genetics and Molecular Biology v.42 n.3 2019
reponame:Genetics and Molecular Biology
instname:Sociedade Brasileira de Genética (SBG)
instacron:SBG
instname_str Sociedade Brasileira de Genética (SBG)
instacron_str SBG
institution SBG
reponame_str Genetics and Molecular Biology
collection Genetics and Molecular Biology
repository.name.fl_str_mv Genetics and Molecular Biology - Sociedade Brasileira de Genética (SBG)
repository.mail.fl_str_mv ||editor@gmb.org.br
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