A new method for quantification of hepatobiliary scintigraphy using 99mTc-mebrofenin. A comparative study
Autor(a) principal: | |
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Data de Publicação: | 2003 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10400.4/979 |
Resumo: | A method based upon the application of mathematical techniques of deconvolution on the classical compartmental model for the quantitative study of liver function from hepatobiliary scintigraphy using 99mTc-mebrofenin data is proposed. The theory in which the method is based upon is presented and a comparison with a published methodology of obtaining the hepatic extraction after scintigraphic sudies has been performed using the results on 36 rats studies obtained with the two methods. A highly significant correlation between the two techniques was verified. The characteristics of the two methodologies, the proposed one based upon a theoretical approach and the other one on an empirical approximation are discussed. Comments are made on the interest and limitations of the presented technique that may be an useful tool for the evaluation of hepatic insufficiency. |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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7160 |
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A new method for quantification of hepatobiliary scintigraphy using 99mTc-mebrofenin. A comparative studyFígadoImagiologia com RadionuclídeosRadiofármacosA method based upon the application of mathematical techniques of deconvolution on the classical compartmental model for the quantitative study of liver function from hepatobiliary scintigraphy using 99mTc-mebrofenin data is proposed. The theory in which the method is based upon is presented and a comparison with a published methodology of obtaining the hepatic extraction after scintigraphic sudies has been performed using the results on 36 rats studies obtained with the two methods. A highly significant correlation between the two techniques was verified. The characteristics of the two methodologies, the proposed one based upon a theoretical approach and the other one on an empirical approximation are discussed. Comments are made on the interest and limitations of the presented technique that may be an useful tool for the evaluation of hepatic insufficiency.RIHUCPedroso de Lima, JPedroso de Lima, JJIsidoro, ILapa, P2011-01-27T12:36:35Z20032003-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.4/979engRev Esp Med Nucl. 2003 Jul-Aug;22(4):244-9.info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-07-11T14:22:10Zoai:rihuc.huc.min-saude.pt:10400.4/979Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T18:03:32.734989Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
A new method for quantification of hepatobiliary scintigraphy using 99mTc-mebrofenin. A comparative study |
title |
A new method for quantification of hepatobiliary scintigraphy using 99mTc-mebrofenin. A comparative study |
spellingShingle |
A new method for quantification of hepatobiliary scintigraphy using 99mTc-mebrofenin. A comparative study Pedroso de Lima, J Fígado Imagiologia com Radionuclídeos Radiofármacos |
title_short |
A new method for quantification of hepatobiliary scintigraphy using 99mTc-mebrofenin. A comparative study |
title_full |
A new method for quantification of hepatobiliary scintigraphy using 99mTc-mebrofenin. A comparative study |
title_fullStr |
A new method for quantification of hepatobiliary scintigraphy using 99mTc-mebrofenin. A comparative study |
title_full_unstemmed |
A new method for quantification of hepatobiliary scintigraphy using 99mTc-mebrofenin. A comparative study |
title_sort |
A new method for quantification of hepatobiliary scintigraphy using 99mTc-mebrofenin. A comparative study |
author |
Pedroso de Lima, J |
author_facet |
Pedroso de Lima, J Pedroso de Lima, JJ Isidoro, I Lapa, P |
author_role |
author |
author2 |
Pedroso de Lima, JJ Isidoro, I Lapa, P |
author2_role |
author author author |
dc.contributor.none.fl_str_mv |
RIHUC |
dc.contributor.author.fl_str_mv |
Pedroso de Lima, J Pedroso de Lima, JJ Isidoro, I Lapa, P |
dc.subject.por.fl_str_mv |
Fígado Imagiologia com Radionuclídeos Radiofármacos |
topic |
Fígado Imagiologia com Radionuclídeos Radiofármacos |
description |
A method based upon the application of mathematical techniques of deconvolution on the classical compartmental model for the quantitative study of liver function from hepatobiliary scintigraphy using 99mTc-mebrofenin data is proposed. The theory in which the method is based upon is presented and a comparison with a published methodology of obtaining the hepatic extraction after scintigraphic sudies has been performed using the results on 36 rats studies obtained with the two methods. A highly significant correlation between the two techniques was verified. The characteristics of the two methodologies, the proposed one based upon a theoretical approach and the other one on an empirical approximation are discussed. Comments are made on the interest and limitations of the presented technique that may be an useful tool for the evaluation of hepatic insufficiency. |
publishDate |
2003 |
dc.date.none.fl_str_mv |
2003 2003-01-01T00:00:00Z 2011-01-27T12:36:35Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10400.4/979 |
url |
http://hdl.handle.net/10400.4/979 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Rev Esp Med Nucl. 2003 Jul-Aug;22(4):244-9. |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
instname_str |
Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
instacron_str |
RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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1799131699123060737 |