Rhabdomyolysis as a manifestation of a metabolic disease: a case report

Detalhes bibliográficos
Autor(a) principal: Moniz, M
Data de Publicação: 2017
Outros Autores: Mascarenhas, MI, Escobar, C, Nunes, P, Abadesso, C, Loureiro, H, Almeida, H
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10400.10/2015
Resumo: Rhabdomyolysis is a process of muscle destruction that can present with varying clinical manifestations. In pediatric patients, its main etiology is infectious diseases. We present a previously healthy adolescent who was admitted to our emergency department with a four-day history of myalgia, muscle weakness and dark urine. At presentation, she was dehydrated. Blood analysis revealed acute renal failure and increased muscular enzymes. She was transferred to our pediatric intensive care unit. Medical therapies for correction of dehydration and the ionic and metabolic consequences of renal failure were performed. Due to oliguria, renal replacement therapy was initiated. An etiological investigation revealed a beta-oxidation defect. Metabolic diseases are a known cause of rhabdomyolysis. Muscular destruction should be diagnosed early in order to avoid its potential consequences. Generally, the treatment of rhabdomyolysis is conservative, although in some situations, a more invasive approach is needed.
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spelling Rhabdomyolysis as a manifestation of a metabolic disease: a case reportRabdomiólise como manifestação de uma doença metabólica: relato de casoRhabdomyolysisMetabolic diseasesAdolescentAcute kidney injuryLesão aguda do rimRhabdomyolysis is a process of muscle destruction that can present with varying clinical manifestations. In pediatric patients, its main etiology is infectious diseases. We present a previously healthy adolescent who was admitted to our emergency department with a four-day history of myalgia, muscle weakness and dark urine. At presentation, she was dehydrated. Blood analysis revealed acute renal failure and increased muscular enzymes. She was transferred to our pediatric intensive care unit. Medical therapies for correction of dehydration and the ionic and metabolic consequences of renal failure were performed. Due to oliguria, renal replacement therapy was initiated. An etiological investigation revealed a beta-oxidation defect. Metabolic diseases are a known cause of rhabdomyolysis. Muscular destruction should be diagnosed early in order to avoid its potential consequences. Generally, the treatment of rhabdomyolysis is conservative, although in some situations, a more invasive approach is needed.Associação de Medicina Intensiva BrasileiraRepositório do Hospital Prof. Doutor Fernando FonsecaMoniz, MMascarenhas, MIEscobar, CNunes, PAbadesso, CLoureiro, HAlmeida, H2018-06-18T15:32:06Z2017-01-01T00:00:00Z2017-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.10/2015engRev Bras Ter Intensiva. 2017 Jan-Mar;29(1):111-114.1982-433510.5935/0103-507X.20170016info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2022-09-20T15:52:44Zoai:repositorio.hff.min-saude.pt:10400.10/2015Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T15:53:01.523856Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Rhabdomyolysis as a manifestation of a metabolic disease: a case report
Rabdomiólise como manifestação de uma doença metabólica: relato de caso
title Rhabdomyolysis as a manifestation of a metabolic disease: a case report
spellingShingle Rhabdomyolysis as a manifestation of a metabolic disease: a case report
Moniz, M
Rhabdomyolysis
Metabolic diseases
Adolescent
Acute kidney injury
Lesão aguda do rim
title_short Rhabdomyolysis as a manifestation of a metabolic disease: a case report
title_full Rhabdomyolysis as a manifestation of a metabolic disease: a case report
title_fullStr Rhabdomyolysis as a manifestation of a metabolic disease: a case report
title_full_unstemmed Rhabdomyolysis as a manifestation of a metabolic disease: a case report
title_sort Rhabdomyolysis as a manifestation of a metabolic disease: a case report
author Moniz, M
author_facet Moniz, M
Mascarenhas, MI
Escobar, C
Nunes, P
Abadesso, C
Loureiro, H
Almeida, H
author_role author
author2 Mascarenhas, MI
Escobar, C
Nunes, P
Abadesso, C
Loureiro, H
Almeida, H
author2_role author
author
author
author
author
author
dc.contributor.none.fl_str_mv Repositório do Hospital Prof. Doutor Fernando Fonseca
dc.contributor.author.fl_str_mv Moniz, M
Mascarenhas, MI
Escobar, C
Nunes, P
Abadesso, C
Loureiro, H
Almeida, H
dc.subject.por.fl_str_mv Rhabdomyolysis
Metabolic diseases
Adolescent
Acute kidney injury
Lesão aguda do rim
topic Rhabdomyolysis
Metabolic diseases
Adolescent
Acute kidney injury
Lesão aguda do rim
description Rhabdomyolysis is a process of muscle destruction that can present with varying clinical manifestations. In pediatric patients, its main etiology is infectious diseases. We present a previously healthy adolescent who was admitted to our emergency department with a four-day history of myalgia, muscle weakness and dark urine. At presentation, she was dehydrated. Blood analysis revealed acute renal failure and increased muscular enzymes. She was transferred to our pediatric intensive care unit. Medical therapies for correction of dehydration and the ionic and metabolic consequences of renal failure were performed. Due to oliguria, renal replacement therapy was initiated. An etiological investigation revealed a beta-oxidation defect. Metabolic diseases are a known cause of rhabdomyolysis. Muscular destruction should be diagnosed early in order to avoid its potential consequences. Generally, the treatment of rhabdomyolysis is conservative, although in some situations, a more invasive approach is needed.
publishDate 2017
dc.date.none.fl_str_mv 2017-01-01T00:00:00Z
2017-01-01T00:00:00Z
2018-06-18T15:32:06Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10400.10/2015
url http://hdl.handle.net/10400.10/2015
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Rev Bras Ter Intensiva. 2017 Jan-Mar;29(1):111-114.
1982-4335
10.5935/0103-507X.20170016
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Associação de Medicina Intensiva Brasileira
publisher.none.fl_str_mv Associação de Medicina Intensiva Brasileira
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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