Rhabdomyolysis as a manifestation of a metabolic disease: a case report
Autor(a) principal: | |
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Data de Publicação: | 2017 |
Outros Autores: | , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10400.10/2015 |
Resumo: | Rhabdomyolysis is a process of muscle destruction that can present with varying clinical manifestations. In pediatric patients, its main etiology is infectious diseases. We present a previously healthy adolescent who was admitted to our emergency department with a four-day history of myalgia, muscle weakness and dark urine. At presentation, she was dehydrated. Blood analysis revealed acute renal failure and increased muscular enzymes. She was transferred to our pediatric intensive care unit. Medical therapies for correction of dehydration and the ionic and metabolic consequences of renal failure were performed. Due to oliguria, renal replacement therapy was initiated. An etiological investigation revealed a beta-oxidation defect. Metabolic diseases are a known cause of rhabdomyolysis. Muscular destruction should be diagnosed early in order to avoid its potential consequences. Generally, the treatment of rhabdomyolysis is conservative, although in some situations, a more invasive approach is needed. |
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Rhabdomyolysis as a manifestation of a metabolic disease: a case reportRabdomiólise como manifestação de uma doença metabólica: relato de casoRhabdomyolysisMetabolic diseasesAdolescentAcute kidney injuryLesão aguda do rimRhabdomyolysis is a process of muscle destruction that can present with varying clinical manifestations. In pediatric patients, its main etiology is infectious diseases. We present a previously healthy adolescent who was admitted to our emergency department with a four-day history of myalgia, muscle weakness and dark urine. At presentation, she was dehydrated. Blood analysis revealed acute renal failure and increased muscular enzymes. She was transferred to our pediatric intensive care unit. Medical therapies for correction of dehydration and the ionic and metabolic consequences of renal failure were performed. Due to oliguria, renal replacement therapy was initiated. An etiological investigation revealed a beta-oxidation defect. Metabolic diseases are a known cause of rhabdomyolysis. Muscular destruction should be diagnosed early in order to avoid its potential consequences. Generally, the treatment of rhabdomyolysis is conservative, although in some situations, a more invasive approach is needed.Associação de Medicina Intensiva BrasileiraRepositório do Hospital Prof. Doutor Fernando FonsecaMoniz, MMascarenhas, MIEscobar, CNunes, PAbadesso, CLoureiro, HAlmeida, H2018-06-18T15:32:06Z2017-01-01T00:00:00Z2017-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.10/2015engRev Bras Ter Intensiva. 2017 Jan-Mar;29(1):111-114.1982-433510.5935/0103-507X.20170016info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2022-09-20T15:52:44Zoai:repositorio.hff.min-saude.pt:10400.10/2015Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T15:53:01.523856Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Rhabdomyolysis as a manifestation of a metabolic disease: a case report Rabdomiólise como manifestação de uma doença metabólica: relato de caso |
title |
Rhabdomyolysis as a manifestation of a metabolic disease: a case report |
spellingShingle |
Rhabdomyolysis as a manifestation of a metabolic disease: a case report Moniz, M Rhabdomyolysis Metabolic diseases Adolescent Acute kidney injury Lesão aguda do rim |
title_short |
Rhabdomyolysis as a manifestation of a metabolic disease: a case report |
title_full |
Rhabdomyolysis as a manifestation of a metabolic disease: a case report |
title_fullStr |
Rhabdomyolysis as a manifestation of a metabolic disease: a case report |
title_full_unstemmed |
Rhabdomyolysis as a manifestation of a metabolic disease: a case report |
title_sort |
Rhabdomyolysis as a manifestation of a metabolic disease: a case report |
author |
Moniz, M |
author_facet |
Moniz, M Mascarenhas, MI Escobar, C Nunes, P Abadesso, C Loureiro, H Almeida, H |
author_role |
author |
author2 |
Mascarenhas, MI Escobar, C Nunes, P Abadesso, C Loureiro, H Almeida, H |
author2_role |
author author author author author author |
dc.contributor.none.fl_str_mv |
Repositório do Hospital Prof. Doutor Fernando Fonseca |
dc.contributor.author.fl_str_mv |
Moniz, M Mascarenhas, MI Escobar, C Nunes, P Abadesso, C Loureiro, H Almeida, H |
dc.subject.por.fl_str_mv |
Rhabdomyolysis Metabolic diseases Adolescent Acute kidney injury Lesão aguda do rim |
topic |
Rhabdomyolysis Metabolic diseases Adolescent Acute kidney injury Lesão aguda do rim |
description |
Rhabdomyolysis is a process of muscle destruction that can present with varying clinical manifestations. In pediatric patients, its main etiology is infectious diseases. We present a previously healthy adolescent who was admitted to our emergency department with a four-day history of myalgia, muscle weakness and dark urine. At presentation, she was dehydrated. Blood analysis revealed acute renal failure and increased muscular enzymes. She was transferred to our pediatric intensive care unit. Medical therapies for correction of dehydration and the ionic and metabolic consequences of renal failure were performed. Due to oliguria, renal replacement therapy was initiated. An etiological investigation revealed a beta-oxidation defect. Metabolic diseases are a known cause of rhabdomyolysis. Muscular destruction should be diagnosed early in order to avoid its potential consequences. Generally, the treatment of rhabdomyolysis is conservative, although in some situations, a more invasive approach is needed. |
publishDate |
2017 |
dc.date.none.fl_str_mv |
2017-01-01T00:00:00Z 2017-01-01T00:00:00Z 2018-06-18T15:32:06Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10400.10/2015 |
url |
http://hdl.handle.net/10400.10/2015 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Rev Bras Ter Intensiva. 2017 Jan-Mar;29(1):111-114. 1982-4335 10.5935/0103-507X.20170016 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Associação de Medicina Intensiva Brasileira |
publisher.none.fl_str_mv |
Associação de Medicina Intensiva Brasileira |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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RCAAP |
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RCAAP |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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1799130396746579968 |