Custo e Carga da Doença de Alzheimer nos Idosos em Portugal
| Autor(a) principal: | |
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| Data de Publicação: | 2021 |
| Outros Autores: | , , , , , , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | por |
| Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
| Texto Completo: | http://hdl.handle.net/10362/137121 |
Resumo: | Funding Information: Financing Support: This work received financial support from Biogen Portugal – Sociedade Farmacêutica Unipessoal Lda.. The funding was not conditional on the nature of the results, which are the sole responsibility of the authors. The study also received scientific support from Sociedade Portuguesa de Neurologia and Grupo de Estudos de Envelhecimento Cerebral e Demência. Publisher Copyright: © Author(s) (or their employer(s)) and Sinapse 2021. Re-use permitted under CC BY-NC. No commercial re-use. |
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Custo e Carga da Doença de Alzheimer nos Idosos em PortugalDisease Burden and Costs Associated with Alzheimer’s Disease in the Elderly in PortugalAlzheimer DiseaseCause of DeathCost of IllnessGlobal Burden of DiseasePortugalQuality-Adjusted Life YearsClinical NeurologyCellular and Molecular NeuroscienceSDG 3 - Good Health and Well-beingFunding Information: Financing Support: This work received financial support from Biogen Portugal – Sociedade Farmacêutica Unipessoal Lda.. The funding was not conditional on the nature of the results, which are the sole responsibility of the authors. The study also received scientific support from Sociedade Portuguesa de Neurologia and Grupo de Estudos de Envelhecimento Cerebral e Demência. Publisher Copyright: © Author(s) (or their employer(s)) and Sinapse 2021. Re-use permitted under CC BY-NC. No commercial re-use.Introduction: Alzheimer’s disease is a progressive, multifactorial neurodegenera-tive brain disorder. Alzheimer’s disease is the main cause of dementia with substan-tial humanistic and economic burden. This study estimated the disease burden and societal costs associated with Alzheimer’s disease in patients aged ≥ 65 years, in mainland Portugal, in 2018. Methods: The burden of disease and cost of illness were estimated using a prev-alence-based approach. Burden of disease was measured in disability-adjusted life years (DALY), estimated as the sum of years of life lost (YLL) due to premature mortality with years lived with disability (YLD). Costs were estimated using a societal perspective and included medical and non-medical direct costs. Results: We estimated 143 334 elderly patients with Alzheimer’s disease in 2018 (7% of the population ≥65 years). In 2018, there were 7538 deaths attributed to Alz-heimer’s disease that resulted in the loss of 76 709 YLL. A total of 45 754 YLD were attributed to Alzheimer’s disease. The overall burden was 122 463 DALY. The estimated direct medical costs attributable to Alzheimer’s disease in 2018 were €219 million (including €166 million for outpatient care, €29 million for inpatient care and €24 million for medication). Non-medical direct costs totalled 1.8 billion (including €1.1 billion attributed to informal care, €551 million for social care, €122 million for sup-port devices, accessories of care and home physical adaptations, and €40 million for transport costs). The total estimated cost amounted to €2 billion in 2018. Conclusion: Alzheimer’s disease has a major socioeconomic impact, being respon-sible for 7% of the total YLL estimated for mainland Portugal. Costs related to informal care represent more than half (54%) of the total costs attributed to Alzheimer´s disease, the latter being equivalent to 1% of the Portuguese gross domestic product.NOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM)RUNCosta, JoãoBorges, MargaridaEncarnação, RosaFirmino, HorácioGonçalves-Pereira, ManuelLindeza, PatríciaSampaio, FilipaSantana, IsabelSousa, RitaTaipa, RicardoVerdelho, AnaSilva-Miguel, Luís2022-04-28T22:34:10Z2021-10-012021-10-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article11application/pdfhttp://hdl.handle.net/10362/137121por1645-281XPURE: 43489949https://doi.org/10.46531/sinapse/AO/210055/2021info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-03-11T05:14:49Zoai:run.unl.pt:10362/137121Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T03:48:48.174629Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
| dc.title.none.fl_str_mv |
Custo e Carga da Doença de Alzheimer nos Idosos em Portugal Disease Burden and Costs Associated with Alzheimer’s Disease in the Elderly in Portugal |
| title |
Custo e Carga da Doença de Alzheimer nos Idosos em Portugal |
| spellingShingle |
Custo e Carga da Doença de Alzheimer nos Idosos em Portugal Costa, João Alzheimer Disease Cause of Death Cost of Illness Global Burden of Disease Portugal Quality-Adjusted Life Years Clinical Neurology Cellular and Molecular Neuroscience SDG 3 - Good Health and Well-being |
| title_short |
Custo e Carga da Doença de Alzheimer nos Idosos em Portugal |
| title_full |
Custo e Carga da Doença de Alzheimer nos Idosos em Portugal |
| title_fullStr |
Custo e Carga da Doença de Alzheimer nos Idosos em Portugal |
| title_full_unstemmed |
Custo e Carga da Doença de Alzheimer nos Idosos em Portugal |
| title_sort |
Custo e Carga da Doença de Alzheimer nos Idosos em Portugal |
| author |
Costa, João |
| author_facet |
Costa, João Borges, Margarida Encarnação, Rosa Firmino, Horácio Gonçalves-Pereira, Manuel Lindeza, Patrícia Sampaio, Filipa Santana, Isabel Sousa, Rita Taipa, Ricardo Verdelho, Ana Silva-Miguel, Luís |
| author_role |
author |
| author2 |
Borges, Margarida Encarnação, Rosa Firmino, Horácio Gonçalves-Pereira, Manuel Lindeza, Patrícia Sampaio, Filipa Santana, Isabel Sousa, Rita Taipa, Ricardo Verdelho, Ana Silva-Miguel, Luís |
| author2_role |
author author author author author author author author author author author |
| dc.contributor.none.fl_str_mv |
NOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM) RUN |
| dc.contributor.author.fl_str_mv |
Costa, João Borges, Margarida Encarnação, Rosa Firmino, Horácio Gonçalves-Pereira, Manuel Lindeza, Patrícia Sampaio, Filipa Santana, Isabel Sousa, Rita Taipa, Ricardo Verdelho, Ana Silva-Miguel, Luís |
| dc.subject.por.fl_str_mv |
Alzheimer Disease Cause of Death Cost of Illness Global Burden of Disease Portugal Quality-Adjusted Life Years Clinical Neurology Cellular and Molecular Neuroscience SDG 3 - Good Health and Well-being |
| topic |
Alzheimer Disease Cause of Death Cost of Illness Global Burden of Disease Portugal Quality-Adjusted Life Years Clinical Neurology Cellular and Molecular Neuroscience SDG 3 - Good Health and Well-being |
| description |
Funding Information: Financing Support: This work received financial support from Biogen Portugal – Sociedade Farmacêutica Unipessoal Lda.. The funding was not conditional on the nature of the results, which are the sole responsibility of the authors. The study also received scientific support from Sociedade Portuguesa de Neurologia and Grupo de Estudos de Envelhecimento Cerebral e Demência. Publisher Copyright: © Author(s) (or their employer(s)) and Sinapse 2021. Re-use permitted under CC BY-NC. No commercial re-use. |
| publishDate |
2021 |
| dc.date.none.fl_str_mv |
2021-10-01 2021-10-01T00:00:00Z 2022-04-28T22:34:10Z |
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info:eu-repo/semantics/publishedVersion |
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info:eu-repo/semantics/article |
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article |
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publishedVersion |
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http://hdl.handle.net/10362/137121 |
| url |
http://hdl.handle.net/10362/137121 |
| dc.language.iso.fl_str_mv |
por |
| language |
por |
| dc.relation.none.fl_str_mv |
1645-281X PURE: 43489949 https://doi.org/10.46531/sinapse/AO/210055/2021 |
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info:eu-repo/semantics/openAccess |
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openAccess |
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11 application/pdf |
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reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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RCAAP |
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RCAAP |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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