Case Report of a Neonate Born to a Mother with Severe SARS-CoV-2 Infection under ECMO

Detalhes bibliográficos
Autor(a) principal: Vilardouro, Ana Sofia
Data de Publicação: 2022
Outros Autores: Castelão, Mafalda, Costa, Paula, Abrantes, Margarida
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/16673
Resumo: Neonatal SARS-CoV-2 infections are rare and although there is some evidence of vertical transmission, most newborns show no clinical signs or present with only mild clinical symptoms. Fetal survival is reported around 70% in mothers submitted to extracorporeal membrane oxygenation. We present a case of a male newborn born at 29 weeks from a mother under extracorporeal membrane oxygenation due to SARS-CoV-2 infection. There was no evidence of vertical transmission, polymerase chain reaction testing of nasopharyngeal/throat swab and polymerase chain reaction testing of blood sample for SARS-CoV-2 were both negative. On day 2, he developed signs of osteomyelitis of the distal femur extremity, which resolved after six weeks of antibiotic therapy, with no other significant events during admission. This case report depicts the favorable outcome of a live infant born to a mother with severe SARS-CoV-2infection under extracorporeal membrane oxygenation.
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spelling Case Report of a Neonate Born to a Mother with Severe SARS-CoV-2 Infection under ECMOCaso Clínico de um Recém-Nascido de Mãe com Infeção Grave por SARS-CoV-2 sob ECMOCOVID-19Extracorporeal Membrane OxygenationInfantNewbornOsteomyelitisSARS-CoV-2COVID-19OsteomieliteOxigenação por Membrana ExtracorpóreaRecém-NascidoSARS-CoV-2Neonatal SARS-CoV-2 infections are rare and although there is some evidence of vertical transmission, most newborns show no clinical signs or present with only mild clinical symptoms. Fetal survival is reported around 70% in mothers submitted to extracorporeal membrane oxygenation. We present a case of a male newborn born at 29 weeks from a mother under extracorporeal membrane oxygenation due to SARS-CoV-2 infection. There was no evidence of vertical transmission, polymerase chain reaction testing of nasopharyngeal/throat swab and polymerase chain reaction testing of blood sample for SARS-CoV-2 were both negative. On day 2, he developed signs of osteomyelitis of the distal femur extremity, which resolved after six weeks of antibiotic therapy, with no other significant events during admission. This case report depicts the favorable outcome of a live infant born to a mother with severe SARS-CoV-2infection under extracorporeal membrane oxygenation.A infeção neonatal por SARS-CoV-2 é rara e apesar de existir alguma evidência da possibilidade de transmissão vertical, a maioria dos recém-nascidos não manifesta quaisquer sinais clínicos ou apresenta apenas sintomas ligeiros. A sobrevivência fetal é de aproximadamente 70% para grávidas que tenham necessitado de oxigenação por membrana extracorporal. Apresentamos um caso de um recém-nascido do sexo masculino, nascido às 29 semanas de idade gestacional de uma mãe sob oxigenação por membrana extracorporal, devido a infeção por SARS-CoV-2. Não se verificou evidência de transmissão vertical, e a reação em cadeia da polimerase de amostras nasofaríngeas e sanguíneas foi negativa. No segundo dia de vida desenvolveu sinais compatíveis com osteomielite da extremidade distal do fémur, resolvidos após seis semanas de antibioticoterapia, sem outras intercorrências relevantes durante a admissão. Este caso revela uma evolução clínica favorável de um recém-nascido, filho de mãe com infeção grave por SARS-CoV-2 sob oxigenação por membrana extracorporal.Ordem dos Médicos2022-04-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttps://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/16673oai:ojs.www.actamedicaportuguesa.com:article/16673Acta Médica Portuguesa; Vol. 35 No. 4 (2022): April; 298-300Acta Médica Portuguesa; Vol. 35 N.º 4 (2022): Abril; 298-3001646-07580870-399Xreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAPenghttps://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/16673https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/16673/6530Direitos de Autor (c) 2022 Acta Médica Portuguesainfo:eu-repo/semantics/openAccessVilardouro, Ana SofiaCastelão, MafaldaCosta, PaulaAbrantes, Margarida2022-12-20T11:07:54Zoai:ojs.www.actamedicaportuguesa.com:article/16673Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T16:20:48.811409Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Case Report of a Neonate Born to a Mother with Severe SARS-CoV-2 Infection under ECMO
Caso Clínico de um Recém-Nascido de Mãe com Infeção Grave por SARS-CoV-2 sob ECMO
title Case Report of a Neonate Born to a Mother with Severe SARS-CoV-2 Infection under ECMO
spellingShingle Case Report of a Neonate Born to a Mother with Severe SARS-CoV-2 Infection under ECMO
Vilardouro, Ana Sofia
COVID-19
Extracorporeal Membrane Oxygenation
Infant
Newborn
Osteomyelitis
SARS-CoV-2
COVID-19
Osteomielite
Oxigenação por Membrana Extracorpórea
Recém-Nascido
SARS-CoV-2
title_short Case Report of a Neonate Born to a Mother with Severe SARS-CoV-2 Infection under ECMO
title_full Case Report of a Neonate Born to a Mother with Severe SARS-CoV-2 Infection under ECMO
title_fullStr Case Report of a Neonate Born to a Mother with Severe SARS-CoV-2 Infection under ECMO
title_full_unstemmed Case Report of a Neonate Born to a Mother with Severe SARS-CoV-2 Infection under ECMO
title_sort Case Report of a Neonate Born to a Mother with Severe SARS-CoV-2 Infection under ECMO
author Vilardouro, Ana Sofia
author_facet Vilardouro, Ana Sofia
Castelão, Mafalda
Costa, Paula
Abrantes, Margarida
author_role author
author2 Castelão, Mafalda
Costa, Paula
Abrantes, Margarida
author2_role author
author
author
dc.contributor.author.fl_str_mv Vilardouro, Ana Sofia
Castelão, Mafalda
Costa, Paula
Abrantes, Margarida
dc.subject.por.fl_str_mv COVID-19
Extracorporeal Membrane Oxygenation
Infant
Newborn
Osteomyelitis
SARS-CoV-2
COVID-19
Osteomielite
Oxigenação por Membrana Extracorpórea
Recém-Nascido
SARS-CoV-2
topic COVID-19
Extracorporeal Membrane Oxygenation
Infant
Newborn
Osteomyelitis
SARS-CoV-2
COVID-19
Osteomielite
Oxigenação por Membrana Extracorpórea
Recém-Nascido
SARS-CoV-2
description Neonatal SARS-CoV-2 infections are rare and although there is some evidence of vertical transmission, most newborns show no clinical signs or present with only mild clinical symptoms. Fetal survival is reported around 70% in mothers submitted to extracorporeal membrane oxygenation. We present a case of a male newborn born at 29 weeks from a mother under extracorporeal membrane oxygenation due to SARS-CoV-2 infection. There was no evidence of vertical transmission, polymerase chain reaction testing of nasopharyngeal/throat swab and polymerase chain reaction testing of blood sample for SARS-CoV-2 were both negative. On day 2, he developed signs of osteomyelitis of the distal femur extremity, which resolved after six weeks of antibiotic therapy, with no other significant events during admission. This case report depicts the favorable outcome of a live infant born to a mother with severe SARS-CoV-2infection under extracorporeal membrane oxygenation.
publishDate 2022
dc.date.none.fl_str_mv 2022-04-01
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/16673
oai:ojs.www.actamedicaportuguesa.com:article/16673
url https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/16673
identifier_str_mv oai:ojs.www.actamedicaportuguesa.com:article/16673
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/16673
https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/16673/6530
dc.rights.driver.fl_str_mv Direitos de Autor (c) 2022 Acta Médica Portuguesa
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Direitos de Autor (c) 2022 Acta Médica Portuguesa
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Ordem dos Médicos
publisher.none.fl_str_mv Ordem dos Médicos
dc.source.none.fl_str_mv Acta Médica Portuguesa; Vol. 35 No. 4 (2022): April; 298-300
Acta Médica Portuguesa; Vol. 35 N.º 4 (2022): Abril; 298-300
1646-0758
0870-399X
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
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instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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